Featured Research

from universities, journals, and other organizations

Caffeine Consumption Not Associated With Breast Cancer Risk In Most Women, Study Suggests

Date:
October 14, 2008
Source:
JAMA and Archives Journals
Summary:
Caffeine consumption does not appear to be associated with overall breast cancer risk, according to a new report. However, there is a possibility of increased risk for women with benign breast disease or for tumors that are hormone-receptor negative or larger than 2 centimeters.

Caffeine consumption does not appear to be associated with overall breast cancer risk, according to a new report. However, there is a possibility of increased risk for women with benign breast disease or for tumors that are hormone-receptor negative or larger than 2 centimeters.

Related Articles


Caffeine is probably the most commonly consumed drug worldwide, present in coffee, tea, chocolate and some medications, according to background information in the article. It was hypothesized that caffeine may increase the risk of breast cancer after a study showed that women with non-cancerous breast disease experienced relief from their symptoms after removing caffeine from their diet.

Ken Ishitani, M.D., Ph.D., of Brigham and Women's Hospital and Harvard Medical School, Boston, and Tokyo Women's Medical University, Japan, and colleagues studied 38,432 women 45 years or older who provided dietary information in 1992-1995. Over an average of 10 years of follow-up, 1,188 of the women developed invasive breast cancer.

"Consumption of caffeine and caffeinated beverages and foods was not statistically significantly associated with overall risk of breast cancer," the authors write. Among women with benign breast disease, a non-significant positive association with breast cancer risk was observed for those in the highest quintile (one-fifth) of caffeine consumption and a significant association was observed for those in the highest category of coffee consumption (four cups or more daily).

Consuming caffeine was also associated with a 68 percent increased risk of estrogen receptor–negative and progesterone receptor–negative breast cancer, or tumors to which the hormones estrogen and progesterone do not bind, and a 79 percent increased risk for breast tumors larger than 2 centimeters.

"The mechanisms by which caffeine may affect breast carcinogenesis [cancer development] are complex and remain unclear," the authors write. "In the present investigation, caffeine consumption was associated with increased risk of breast cancers negative for both estrogen receptors and progesterone receptors or larger than 2 centimeters, which have less favorable prognoses. These findings indicate that caffeine consumption may affect breast cancer progression, and such an effect may be independent of the estrogen pathway." Further study is required to better understand caffeine's role, they note.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ken Ishitani, MD, PhD; Jennifer Lin, PhD; JoAnn E. Manson, MD, DrPH; Julie E. Buring, ScD; Shumin M. Zhang, MD, ScD. Caffeine Consumption and the Risk of Breast Cancer in a Large Prospective Cohort of Women. Archives of Internal Medicine, 2008; 168 (18): 2022 DOI: 10.1001/archinte.168.18.2022

Cite This Page:

JAMA and Archives Journals. "Caffeine Consumption Not Associated With Breast Cancer Risk In Most Women, Study Suggests." ScienceDaily. ScienceDaily, 14 October 2008. <www.sciencedaily.com/releases/2008/10/081013171427.htm>.
JAMA and Archives Journals. (2008, October 14). Caffeine Consumption Not Associated With Breast Cancer Risk In Most Women, Study Suggests. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2008/10/081013171427.htm
JAMA and Archives Journals. "Caffeine Consumption Not Associated With Breast Cancer Risk In Most Women, Study Suggests." ScienceDaily. www.sciencedaily.com/releases/2008/10/081013171427.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins