Featured Research

from universities, journals, and other organizations

New Hope For A Better Treatment For Childhood Cancer

Date:
October 21, 2008
Source:
University of Nottingham
Summary:
Children who are diagnosed with cancer could benefit from better diagnosis and treatment in the future, thanks to a new research project.

Children who are diagnosed with cancer could benefit from better diagnosis and treatment in the future, thanks to a new research project involving clinicians and scientists at The University of Nottingham.

Experts at the University are part of the Children’s Cancer and Leukaemia Group which has just secured 2.5 million pounds from Cancer Research UK and the Engineering and Physical Sciences Research Council. They will use the money over the next five years to develop and test new ways of scanning childhood tumours in depth to give doctors a more detailed diagnosis. It will also give them a better indication of how to treat the tumour and whether it will respond to new drugs.

The grant is part of a nationwide investment of 50m to establish four large cancer imaging centres and five cancer imaging research programmes. The cancer imaging initiative will help the development and introduction of the latest imaging technologies to help advances in basic and clinical cancer research.

Cancer is the most common cause of death from disease in children with most cases involving solid tumours. Around 1,500 children are diagnosed every year in the UK. At present conventional Magnetic Resonance Imaging (MRI) is the usual technique for scanning of patients but it provides limited, mainly anatomical, information. This research project will look at how more accurate ways of analysing tumours, using Magnetic Resonance Spectroscopy (MRS) and Diffusion/Perfusion MRI of tumour tissue, can be better and more widely used by doctors treating children with cancer. Diffusion MRI measures the molecular mobility of water in tissue, while perfusion MRI measures the rate at which blood is delivered to tissue. It gives a much clearer picture of the nature and composition of the tumour in a non-invasive way. Treatment can then be more accurately tailored.

The Children’s Cancer and Leukaemia Group, funded by Cancer Research UK, runs clinical trials for paediatric cancer at specialist centres across the UK. It has formed a Functional Imaging Group to develop the use of the techniques in treating children with brain tumours. This significant new grant means the group’s research can be extended to examine other Magnetic Resonance methods and their use on tumours in the rest of the body. The information will be disseminated and evaluated through the group’s established clinical trials network in the UK. This will make sure as many children as possible benefit from the latest MRI technology.

Professor of Paediatric Neuro-Oncology, Richard Grundy, from Nottingham University Medical School, said: “We all delighted that we have won this grant. Fortunately cancer in children is relatively uncommon compared to adults, reinforcing the need to develop and test the role of new techniques or treatments as a collaborative effort. This important grant from Cancer Research UK and the EPSRC allows us to investigate advanced Magnetic Resonance imaging to improve our understanding and treatment of childhood cancer. This funding and recognition of NUH should also help our aspirations locally to develop an imaging centre dedicated for children as part of the new Nottingham Children’s Hospital development.”

Professor Herbie Newell, Director of Translational Research at Cancer Research UK, said: “Imaging is an invaluable tool in the fight against cancer. Being able to see what’s happening inside cells is vitally important in understanding how treatments are currently working and the best ways to improve them.”


Story Source:

The above story is based on materials provided by University of Nottingham. Note: Materials may be edited for content and length.


Cite This Page:

University of Nottingham. "New Hope For A Better Treatment For Childhood Cancer." ScienceDaily. ScienceDaily, 21 October 2008. <www.sciencedaily.com/releases/2008/10/081017082017.htm>.
University of Nottingham. (2008, October 21). New Hope For A Better Treatment For Childhood Cancer. ScienceDaily. Retrieved April 20, 2014 from www.sciencedaily.com/releases/2008/10/081017082017.htm
University of Nottingham. "New Hope For A Better Treatment For Childhood Cancer." ScienceDaily. www.sciencedaily.com/releases/2008/10/081017082017.htm (accessed April 20, 2014).

Share This



More Health & Medicine News

Sunday, April 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins