Featured Research

from universities, journals, and other organizations

Preoperative Radiation May Improve Survival Rates In Advanced Rectal Cancer Patients

Date:
December 4, 2008
Source:
Geisinger Health System
Summary:
A new study shows that preoperative treatment for rectal cancer shouldn't be a "one sized fits all approach." After reviewing nine recent studies, investigators concluded that physicians need to consider a variety of factors such as tumor size, cancer stage and patient preference before deciding on the course of preoperative treatment.

Patients treated with radiation prior to surgery for advanced rectal cancer have fewer instances of cancer recurrence and better overall survival rates, according to a recent Geisinger report.

The report examined a treatment called neoadjuvant therapy, which can reduce cancerous tumor size or limit the spread of cancer, before surgery to remove the tumor. Neoadjuvant therapy may include chemotherapy and/or radiation.

Neoadjuvant therapy should not be considered a "one size fits all" approach for rectal cancer patients, said the report's primary author, Mohammed Mohiuddin, MD, FRCR, FACR. Dr Mohiuddin is director of The Henry Cancer Center and co-director of Geisinger Health System's Cancer Institute.

"Physicians need to consider a variety of factors such as tumor size, cancer stage and patient preference before deciding on the course of preoperative treatment," said Dr. Mohiuddin, who has published extensively on the topic of radiation oncology.

The report compared the results of nine recently published research studies involving several thousand cancer patients in Europe and the United States.

Giving comparatively higher dosages of radiation reduces the likelihood that the cancer returns to the same place in the body, the report said. Short-term radiation therapy in some patients may be more convenient because it reduces the number of trips to the hospital.

In patients with late stage rectal cancer, the report supports the pre-surgical practice of combining chemotherapy with smaller radiation dosages over several weeks.

The report appears in the November edition of the International Journal of Radiation Oncology Biology Physics. Drs John Marks and Gerald Marks of the Lankenau Institute for Medical Research in Wynnewood, PA served as report co-authors.


Story Source:

The above story is based on materials provided by Geisinger Health System. Note: Materials may be edited for content and length.


Cite This Page:

Geisinger Health System. "Preoperative Radiation May Improve Survival Rates In Advanced Rectal Cancer Patients." ScienceDaily. ScienceDaily, 4 December 2008. <www.sciencedaily.com/releases/2008/12/081202115150.htm>.
Geisinger Health System. (2008, December 4). Preoperative Radiation May Improve Survival Rates In Advanced Rectal Cancer Patients. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2008/12/081202115150.htm
Geisinger Health System. "Preoperative Radiation May Improve Survival Rates In Advanced Rectal Cancer Patients." ScienceDaily. www.sciencedaily.com/releases/2008/12/081202115150.htm (accessed April 19, 2014).

Share This



More Health & Medicine News

Saturday, April 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins