Featured Research

from universities, journals, and other organizations

Fat Tissue Is Sensitive To Irradiation

Date:
January 5, 2009
Source:
American Journal of Pathology
Summary:
Scientists found that irradiation damages fat tissue. Radiation therapy directed at cancer management also damages normal tissues. Autologous transplant of tissues such as fat tissue has often been used to prevent the fibrosis, organ dysfunction, and necrosis that result from radiation treatment; however, the effects of radiation on the transplanted fat tissue had not been studied.

Researchers led by Dr. B้atrice Cousin at Institut Louis Bugnard found that irradiation damages fat tissue. 

Radiation therapy directed at cancer management also damages normal tissues. Autologous transplant of tissues such as fat tissue has often been used to prevent the fibrosis, organ dysfunction, and necrosis that result from radiation treatment; however, the effects of radiation on the transplanted fat tissue had not been studied.

Dr. Cousin's group characterized adipose tissue isolated from mice after total body irradiation. They found that fat pads weighed significantly less post-irradiation and had decreased adipocyte size and a reduced number of mature adipocytes. Poglio et al also observed severe decreases in the number of proliferating cells and increases in the number of dying cells.

Taken together, the data from Dr. Cousin's group suggest that "in terms of therapeutics, these acute affects may modify the reconstructive capacity of adipose tissue and therefore its use in autologous fat tissue transfer after irradiation." These results call into question the effectiveness of transplanting adipose tissue during radiation therapy.


Story Source:

The above story is based on materials provided by American Journal of Pathology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Poglio S, Galvani S, Bour S, Andr้ M, Prunet-Marcassus B, P้nicaud L, Casteilla L, Cousin B. Adipose Tissue Sensitivity to Radiation Exposure. Am J Pathol, 174:44-53

Cite This Page:

American Journal of Pathology. "Fat Tissue Is Sensitive To Irradiation." ScienceDaily. ScienceDaily, 5 January 2009. <www.sciencedaily.com/releases/2008/12/081230074657.htm>.
American Journal of Pathology. (2009, January 5). Fat Tissue Is Sensitive To Irradiation. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/2008/12/081230074657.htm
American Journal of Pathology. "Fat Tissue Is Sensitive To Irradiation." ScienceDaily. www.sciencedaily.com/releases/2008/12/081230074657.htm (accessed September 2, 2014).

Share This




More Health & Medicine News

Tuesday, September 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

Newsy (Sep. 2, 2014) — The U.N. says the problem is two-fold — quarantine zones and travel restrictions are limiting the movement of both people and food. Video provided by Newsy
Powered by NewsLook.com
Get on Your Bike! London Cycling Popularity Soars Despite Danger

Get on Your Bike! London Cycling Popularity Soars Despite Danger

AFP (Sep. 1, 2014) — Wedged between buses, lorries and cars, cycling in London isn't for the faint hearted. Nevertheless the number of people choosing to bike in the British capital has doubled over the past 15 years. Duration: 02:27 Video provided by AFP
Powered by NewsLook.com
Can You Train Your Brain To Eat Healthy?

Can You Train Your Brain To Eat Healthy?

Newsy (Sep. 1, 2014) — New research says if you condition yourself to eat healthy foods, eventually you'll crave them instead of junk food. Video provided by Newsy
Powered by NewsLook.com
We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) — A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins