Featured Research

from universities, journals, and other organizations

Drug Improves Memory In Alzheimer's Disease, Animal Study Suggests

Date:
February 24, 2009
Source:
Basque Research
Summary:
A drug used in a type of hereditary metabolic disorder improved the memory of laboratory animals with Alzheimer's disease.

A drug used in a type of hereditary metabolic disorder improved the memory of laboratory animals with Alzheimer’s disease. The results of the project, developed by researchers of the Center for Applied Medical Research (CIMA) of the University of Navarra have been published in the journal Neuropsychopharmacology.

The research project showed that the drug sodium phenylbutyrate, prescribed until now for patients with alterations in the urea cycle, eases the fusion of proteins responsible for neuron connections, thus increasing the learning capacity of the mice involved. As a result, these discoveries offer new, promising perspectives for the treatment of Alzheimer’s Disease and other related dementias.

In addition, these findings provide a new alternative to the drugs that are currently available for fighting this devastating disease, explained Dr. Ana García-Osta. Dr. García-Osta is a researcher from the Department of Neurosciences and the principal author of this project.

The research team is currently focused on discovering the acting mechanism in this drug. As the drug is now clinically available and well tolerated, the confirmation of its therapeutic affectivity in humans could be applied to Alzheimer’s in a shorter period of time than other drugs being studied.

Alzheimer’s disease is a neurodegenerative disorder associated with age and characterized by the progressive deterioration of cognitive and intellectual abilities. “Cognitive deficit is associated with a loss of neuron connections. For the memory to develop, it is necessary for a series of cellular and molecular mechanisms to be activated. The interruption of these processes affects the capacity to assimilate and store new memories, explained Dr. García-Osta.


Story Source:

The above story is based on materials provided by Basque Research. Note: Materials may be edited for content and length.


Cite This Page:

Basque Research. "Drug Improves Memory In Alzheimer's Disease, Animal Study Suggests." ScienceDaily. ScienceDaily, 24 February 2009. <www.sciencedaily.com/releases/2009/02/090218103515.htm>.
Basque Research. (2009, February 24). Drug Improves Memory In Alzheimer's Disease, Animal Study Suggests. ScienceDaily. Retrieved July 26, 2014 from www.sciencedaily.com/releases/2009/02/090218103515.htm
Basque Research. "Drug Improves Memory In Alzheimer's Disease, Animal Study Suggests." ScienceDaily. www.sciencedaily.com/releases/2009/02/090218103515.htm (accessed July 26, 2014).

Share This




More Mind & Brain News

Saturday, July 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

University Quiz Implies Atheists Are Smarter Than Christians

University Quiz Implies Atheists Are Smarter Than Christians

Newsy (July 25, 2014) — An online quiz from a required course at Ohio State is making waves for suggesting atheists are inherently smarter than Christians. Video provided by Newsy
Powered by NewsLook.com
Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) — A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) — The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Can Watching TV Make You Feel Like A Failure?

Can Watching TV Make You Feel Like A Failure?

Newsy (July 24, 2014) — A study by German researchers claims watching TV while you're stressed out can make you feel guilty and like a failure. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins