Featured Research

from universities, journals, and other organizations

Liver Cancer Incidence Has Tripled Since 1970s, But Survival Rates Improving

Date:
February 18, 2009
Source:
American Society of Clinical Oncology
Summary:
Hepatocellular carcinoma (liver cancer) incidence and mortality have increased substantially in the United States over the past three decades, but survival rates are improving.

A new study examining data on incidence trends, mortality rates and survival rates from the National Cancer Institute’s Surveillance Epidemiology and End Results (SEER) cancer registries indicates that the incidence of liver cancer in the United States tripled between 1975 and 2005.

Researchers also found for the first time that one- through five-year survival rates improved significantly for patients diagnosed with liver cancer between 1992 and 2005, in part because more patients were diagnosed at earlier stages, when treatment is more effective. Earlier diagnosis may be due to increasing awareness and screening to detect localized disease in patients at risk for liver cancer.

“Although the study could not determine why liver incidence rates are increasing, these trends may be partially attributable to an increase in chronic hepatitis C, which together with hepatitis B is a major risk factor for liver cancer,” said Dr. Sean Altekruse, an Epidemiologist with the NCI’s SEER Program and the study’s lead author. “Additional research into the factors related to this increase in incidence will be vital to preventing these rates from rising further.” Dr. Altekruse noted that heavy alcohol consumption, fatty liver disease, obesity, diabetes mellitus and iron storage diseases may also contribute to the increasing incidence of liver cancer.

The study found that between 1975 and 2005, liver cancer rates tripled, from 1.6 cases per 100,000 people to 4.9 per 100,000. From 1992 to 2005, liver cancer incidence trends increased significantly:

  • African-Americans and Hispanics both experienced an approximately 67 percent increase in liver cancer incidence between 1992 and 2005 (4.2 to 7.0/100,000 and 4.8 to 8.0/100,000, respectively), and whites experienced an approximately 50 percent increase in incidence (2.6 to 3.9/100,000) during this time period.
  • Between 2000 and 2005, incidence rates increased most markedly among African-American men (42 percent, 28.7 to 40.8/100,000), Hispanic men (43 percent, 23 to 32.8/100,000), and white men (43 percent, (11.5 to 16.5/100,000) 50 to 59 years of age. These increases may be partially due to an epidemic of hepatitis C infection that began in the 1960s, when men in this age range were young adults.
  • From 1992 to 2005, liver cancer incidence rates among Asians and Pacific Islanders were the highest of all racial groups overall; however, rates increased by a relatively modest 17 percent (10.0 to 11.7/100,000) in this time period. Researchers attribute a substantial portion of liver cancer cases in Asians and Pacific Islanders to higher rates of hepatitis B among some Asian subgroups.
  • One-year survival rates nearly doubled between 1992 and 2005, rising from 25 percent of patients to 47 percent. Dr. Altekruse points out that while the increasing survival rates are encouraging, further improvement is still needed, noting that one-year survival rates are still below 50 percent.

ASCO Perspective

Jennifer Obel, ASCO official and Attending Physician, NorthShore University HealthSystem said, “Early screening for patients with hepatitis C, a leading risk factor for liver cancer, has directly contributed to increasing survival rates for patients living with liver cancer. When detected early, there are significantly more treatment options for liver cancer – in most cases, the earlier it is caught, the better the prognosis. This study points to the need to identify even more at-risk individuals through early screening programs to improve prognosis with potentially curative therapy.”


Story Source:

The above story is based on materials provided by American Society of Clinical Oncology. Note: Materials may be edited for content and length.


Cite This Page:

American Society of Clinical Oncology. "Liver Cancer Incidence Has Tripled Since 1970s, But Survival Rates Improving." ScienceDaily. ScienceDaily, 18 February 2009. <www.sciencedaily.com/releases/2009/02/090218114318.htm>.
American Society of Clinical Oncology. (2009, February 18). Liver Cancer Incidence Has Tripled Since 1970s, But Survival Rates Improving. ScienceDaily. Retrieved September 3, 2014 from www.sciencedaily.com/releases/2009/02/090218114318.htm
American Society of Clinical Oncology. "Liver Cancer Incidence Has Tripled Since 1970s, But Survival Rates Improving." ScienceDaily. www.sciencedaily.com/releases/2009/02/090218114318.htm (accessed September 3, 2014).

Share This



More Health & Medicine News

Wednesday, September 3, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Snack Attack: Study Says Action Movies Make You Snack More

Snack Attack: Study Says Action Movies Make You Snack More

Newsy (Sep. 2, 2014) You're more likely to gain weight while watching action flicks than you are watching other types of programming, says a new study published in JAMA. Video provided by Newsy
Powered by NewsLook.com
U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

Newsy (Sep. 2, 2014) The U.N. says the problem is two-fold — quarantine zones and travel restrictions are limiting the movement of both people and food. Video provided by Newsy
Powered by NewsLook.com
Doctors Fear They're Losing Battle Against Ebola

Doctors Fear They're Losing Battle Against Ebola

AP (Sep. 2, 2014) As a third American missionary is confirmed to have contracted Ebola in Liberia, doctors on the ground in West Africa fear they're losing the battle against the outbreak. (Sept. 2) Video provided by AP
Powered by NewsLook.com
Tech Giants Bet on 3D Headsets for Gaming, Healthcare

Tech Giants Bet on 3D Headsets for Gaming, Healthcare

AFP (Sep. 2, 2014) When Facebook acquired the virtual reality hardware developer Oculus VR in March for $2 billion, CEO Mark Zuckerberg hailed the firm's technology as "a new communication platform." Duration: 02:24 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins