Featured Research

from universities, journals, and other organizations

How Cranberry Products Prevent Urinary Tract Infections

Date:
March 12, 2009
Source:
Mary Ann Liebert, Inc./Genetic Engineering News
Summary:
Chemicals present in cranberries -- and not the acidity of cranberry juice, as previously thought -- prevent infection-causing bacteria from attaching to the cells that line the urinary tract.

Chemicals present in cranberries — and not the acidity of cranberry juice, as previously thought — prevent infection-causing bacteria from attaching to the cells that line the urinary tract.
Credit: iStockphoto/Stepan Popov

Chemicals present in cranberries—and not the acidity of cranberry juice, as previously thought—prevent infection-causing bacteria from attaching to the cells that line the urinary tract, as documented in a report published in Journal of Medicinal Food.

Related Articles


Urinary tract infections (UTIs) burden the healthcare system with more than $2 billion in treatment costs each year and are a common problem in patients with a urinary catheter in place. Adhesion of E. coli bacteria to cells lining the urinary tract is the first step in the development of a UTI. Chemicals found in cranberry products called proanthocyanidins (PACs) prevent E. coli, which is the cause of about 85% of UTIs and 90% of cases of acute pyelonephritis, from adhering to these urinary tract epithelial cells by affecting the surface properties of the bacteria.

Paola Pinzσn-Arango, Yatao Liu, and Terri Camesano, from Worcester Polytechnic Institute, in Massachusetts, exposed E. coli grown in culture to either light cranberry juice cocktail or cranberry PACs and measured the adhesion forces between the bacteria and a silicon surface using atomic force microscopy. They demonstrated that the longer the bacteria were exposed to either the cranberry juice or the PACS the greater the decrease in bacterial attachment. In the article entitled, "Role of Cranberry on Bacterial Adhesion Forces and Implications for Escherichia coli—Uroepithelial Cell Attachment," the authors also concluded that this effect was reversible, and that bacteria regrown in an environment without cranberry juice or PACS regained the ability to attach to the model surface.

"Cranberries, one of only three species of fruits native to North America, has a long history of medicinal food use. Native Americans used the fruit for the treatment of bladder and kidney ailments hundreds of years ago. The article by Camesano and co-workers is a milestone in the understanding of its mechanism of action," says Sheldon S. Hendler, PhD, MD, Co-Editor-in-Chief of the Journal, and Clinical Professor of Medicine, University of California, San Diego.


Story Source:

The above story is based on materials provided by Mary Ann Liebert, Inc./Genetic Engineering News. Note: Materials may be edited for content and length.


Cite This Page:

Mary Ann Liebert, Inc./Genetic Engineering News. "How Cranberry Products Prevent Urinary Tract Infections." ScienceDaily. ScienceDaily, 12 March 2009. <www.sciencedaily.com/releases/2009/03/090309121937.htm>.
Mary Ann Liebert, Inc./Genetic Engineering News. (2009, March 12). How Cranberry Products Prevent Urinary Tract Infections. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2009/03/090309121937.htm
Mary Ann Liebert, Inc./Genetic Engineering News. "How Cranberry Products Prevent Urinary Tract Infections." ScienceDaily. www.sciencedaily.com/releases/2009/03/090309121937.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) — Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
The Hottest Food Trends for 2015

The Hottest Food Trends for 2015

Buzz60 (Dec. 17, 2014) — Urbanspoon predicts whicg food trends will dominate the culinary scene in 2015. Mara Montalbano (@maramontalbano) has the story. Video provided by Buzz60
Powered by NewsLook.com
Rover Finds More Clues About Possible Life On Mars

Rover Finds More Clues About Possible Life On Mars

Newsy (Dec. 17, 2014) — NASA's Curiosity rover detected methane on Mars and organic compounds on the surface, but it doesn't quite prove there was life ... yet. Video provided by Newsy
Powered by NewsLook.com
Ivory Trade Boom Swamps Law Efforts

Ivory Trade Boom Swamps Law Efforts

Reuters - Business Video Online (Dec. 17, 2014) — Demand for ivory has claimed the lives of tens of thousands of African elephants and now a conservation report says the illegal trade is overwhelming efforts to enforce the law. Amy Pollock reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins