Featured Research

from universities, journals, and other organizations

Feeling Tired? Study Finds Prevalence Of Anergia In People With Failing Hearts

Date:
March 13, 2009
Source:
Columbia University Medical Center
Summary:
A noninvasive method of monitoring human activity is helping doctors and researchers shed new light on a syndrome affecting nearly 40 percent of older adults with heart failure: anergia. Anergia, or lack of energy, is a newly delineated, criterion-based geriatric syndrome that is often overlooked or dismissed by doctors and patients alike as simply a natural tiredness associated with "old age."

With the help of a non-invasive method of monitoring human activity, doctors and researchers at Columbia University Medical Center are shedding new light on a syndrome affecting nearly 40 percent of older adults with heart failure: anergia.

Anergia, or lack of energy, is a newly delineated, criterion-based geriatric syndrome that is often overlooked or dismissed by doctors and patients alike as simply a natural tiredness associated with "old age."

Whether anergia is a result of heart failure or perhaps a potential underlying contributing factor is not entirely clear. However, one thing is certain, researchers say: Fatigue has been shown to have independent long-term prognostic implications in patients with heart failure, suggesting that fatigue needs to be effectively evaluated not only because symptom alleviation is a target for treatment, but also because of the potential for the treatment of fatigue to influence the prognosis in patients with heart failure.

Mathew Maurer, M.D., associate professor of clinical medicine at Columbia University Medical Center, is the senior author of the study being published in the March 2009 edition of the Journal of Cardiac Failure.

As part of the nine-month prospective cohort study, heart failure patients were provided an actigraph – a device worn on the wrist like a watch that was used to assess physical activity, energy expenditures and sleep by measuring and recording limb movement.

Participants were instructed to wear it continuously on their non-dominant wrist for the nine months of the study. At baseline and at every three months for a total of four visits, each subject underwent a targeted physical exam including review of concomitant medications, co-morbid diagnoses, measurement of heart failure severity and distance walked during a six-minute hall walk as well as other mediating factors that might influence activity levels.

An earlier study by Dr. Maurer and the Stroud Center for the Studies of Quality of Life at Columbia University showed that anergia may stem from many conditions, including heart and kidney dysfunction, arthritis, lung disease, anemia and depression.

In the current study, Dr. Maurer, together with Susan Delisle, NP, and the Healthcare Innovation and Technology Lab at Columbia University, found significant discrepancies between self-reported fatigue and actigraphy readings, suggesting that these readings provide complimentary and important information about the link between heart failure, sleep disorders and impairments in health-related quality of life that may be operative through anergia.

Encouraged by the results, Maurer and his team have applied for a $2 million NIH grant to gather more data to further study the origins and challenges of treating anergia.

"The overall goal of our current research efforts is to develop methods to evaluate and assess the causal or contributing factors of anergia in order to develop interventions to decrease morbidity and mortality due to this syndrome," Dr. Maurer says.


Story Source:

The above story is based on materials provided by Columbia University Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

Columbia University Medical Center. "Feeling Tired? Study Finds Prevalence Of Anergia In People With Failing Hearts." ScienceDaily. ScienceDaily, 13 March 2009. <www.sciencedaily.com/releases/2009/03/090311162805.htm>.
Columbia University Medical Center. (2009, March 13). Feeling Tired? Study Finds Prevalence Of Anergia In People With Failing Hearts. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2009/03/090311162805.htm
Columbia University Medical Center. "Feeling Tired? Study Finds Prevalence Of Anergia In People With Failing Hearts." ScienceDaily. www.sciencedaily.com/releases/2009/03/090311162805.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Newsy (July 23, 2014) An 8-year-old boy helped his younger brother, who has a rare genetic condition that's confined him to a wheelchair, finish a triathlon. Video provided by Newsy
Powered by NewsLook.com
Stone Fruit Listeria Scare Causes Sweeping Recall

Stone Fruit Listeria Scare Causes Sweeping Recall

Newsy (July 22, 2014) The Wawona Packing Company has issued a voluntary recall on the stone fruit it distributes due to a possible Listeria outbreak. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com
CDC Head Concerned About a Post-Antibiotic Era

CDC Head Concerned About a Post-Antibiotic Era

AP (July 22, 2014) Sounding alarms about the growing threat of antibiotic resistance, CDC Director Tom Frieden warned Tuesday if the global community does not confront the problem soon, the world will be living in a devastating post-antibiotic era. (July 22) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins