Featured Research

from universities, journals, and other organizations

Long-term Complications Of Melamine Consumption In Children

Date:
May 1, 2009
Source:
American Urological Association
Summary:
Children with a history of consuming melamine-contaminated milk powder are at an increased risk of developing kidney stones and other urological complications. Researchers found that melamine calculus occurred mostly in infants at six months to 18 months after consuming melamine-contaminated milk powder after birth but that the stones could be effectively managed with noninvasive treatment.

Children with a history of consuming melamine-contaminated milk powder are at an increased risk of developing kidney stones and other urological complications. Researchers presenting two studies at the 104th Annual Scientific Meeting of the American Urological Association (AUA) found that melamine calculus occurred mostly in infants at six months to 18 months after consuming melamine-contaminated milk powder after birth but that the stones could be effectively managed with noninvasive treatment.

In the first study, researchers analyzed the clinical data of 50 young children with double kidney stones who had a history of consuming melamine-contaminated milk powder. Researchers studied ultrasound images from each child, measuring kidney stone size, number, shape and location. Eighty-five percent of these cases occurred in children ages six to 18 months. Of these 50 children, 42 formed kidney stones in both kidneys; multiple stones were found in 18 children; and single stones were found in nine of them. Eleven children experienced kidney failure, in which the stone diameters of bilateral kidneys were significantly larger than those who did not experience kidney failure. In 21 cases, the stone was passed after non-operative hospital treatment in an average of eight days.

Researchers in the second study analyzed the clinical data of 165 infants, aged 50 days to three years, with urinary stones who had a history of consuming melamine-contaminated milk powder. The children were divided into mild (25 cases), moderate (122 cases) and severe (18 cases) groups. Researchers found that the peak incidence of urolithiasis (urinary stones) was found in children aged six months to 12 months.

Of these patients, 50.3 percent were asymptomatic, 16.9 percent experienced dysuria (painful urination), 14.6 percent had infantile colic, 10.9 percent experienced oliguria or anuria (decreased urine and absence of urine, respectively) and 7.3 percent had hematuria (blood in the urine). Acute urinary retention (the sudden inability to urinate) caused by urethral stones was found in five cases. The stone diameter ranged from 22mm to 16mm, and 63.5 percent of cases had 4-10 mm stones. All cases accepted non-operative treatment, except those cases with a bilateral stone and obstruction. After hospital treatment, the stone expulsion rate was 43 percent.

"This study presents us with the long-term complications for children who had been fed with melamine contaminated products," said Anthony Atala, MD, an AUA spokesman. "Both parents and physicians should be vigilant of these signs and symptoms in children who may have consumed the contaminated milk powder."

Wen, J; Li, Z; Zhang, H; Wang, Y; Wang, J; Fan, Y. The Clinical Analysis of Double Renal Calculus in 50 Infants Fed Melamine Contaminated Milk Powder. J Urol, suppl. 2009: 181, 4, abstract 1060.

Wen, J; Yang, H; Wang, Y; Wang, G. The Clinical Analysis of Urolithiasis in 165 Infants and Children with History of Feeding Melamine Contaminated Milk Powder. J Urol, suppl. 2009: 181, 4, abstract 1061.


Story Source:

The above story is based on materials provided by American Urological Association. Note: Materials may be edited for content and length.


Cite This Page:

American Urological Association. "Long-term Complications Of Melamine Consumption In Children." ScienceDaily. ScienceDaily, 1 May 2009. <www.sciencedaily.com/releases/2009/04/090426075238.htm>.
American Urological Association. (2009, May 1). Long-term Complications Of Melamine Consumption In Children. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2009/04/090426075238.htm
American Urological Association. "Long-term Complications Of Melamine Consumption In Children." ScienceDaily. www.sciencedaily.com/releases/2009/04/090426075238.htm (accessed October 1, 2014).

Share This



More Health & Medicine News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Some Positive Ebola News: Outbreak 'Contained' In Nigeria

Some Positive Ebola News: Outbreak 'Contained' In Nigeria

Newsy (Sep. 30, 2014) The CDC says a new case of Ebola has not been reported in Nigeria for more than 21 days, leading to hopes the outbreak might be nearing its end. Video provided by Newsy
Powered by NewsLook.com
UN Ebola Mission Head: Immediate Action Is Crucial

UN Ebola Mission Head: Immediate Action Is Crucial

AFP (Sep. 30, 2014) The newly appointed head of the United Nations Mission for Ebola Emergency Response (UNMEER), Anthony Banbury, outlines operations to tackle the virus. Duration: 00:39 Video provided by AFP
Powered by NewsLook.com
CDC Confirms First Case of Ebola in US

CDC Confirms First Case of Ebola in US

AP (Sep. 30, 2014) The CDC has confirmed the first diagnosed case of Ebola in the United States. The patient is being treated at a Dallas hospital after traveling earlier this month from Liberia. (Sept. 30) Video provided by AP
Powered by NewsLook.com
New Breast Cancer Drug Extends Lives In Clinical Trial

New Breast Cancer Drug Extends Lives In Clinical Trial

Newsy (Sep. 30, 2014) In a clinical trial, breast cancer patients lived an average of 15 months longer when they received new drug Perjeta along with Herceptin. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins