Featured Research

from universities, journals, and other organizations

Sublingual Immunotherapy For Inhalant Allergies Deserves Deeper Consideration, Experts Urge

Date:
May 6, 2009
Source:
American Academy of Otolaryngology -- Head and Neck Surgery
Summary:
Sublingual immunotherapy for the treatment of allergy symptoms caused by a wide variety of environmental inhalants has been effectively used in Europe. It should be employed to further treatment of allergies in the United States, where allergic symptoms are largely undertreated, according to some experts.

Sublingual immunotherapy for the treatment of allergy symptoms caused by a wide variety of environmental inhalants has been effectively used in Europe. It should be employed to further treatment of allergies in the United States, where allergic symptoms are largely undertreated, according to an invited article in the April 2009 issue of Otolaryngology-Head and Neck Surgery. A response to the article, published in the same journal issue, expresses cautious optimism, but calls for additional research.

Related Articles


Sublingual immunotherapy (SLIT) involves the administering of an allergen solution under the tongue, which in time reduces the patient's sensitivity to those allergens. The more prevalent alternative is subcutaneous immunotherapy, usually administered through an injection.

The authors of the invited article note that despite allergic symptoms contributing heavily to poor quality of life, high socioeconomic costs, and increased health issues, these syndromes remain underdiagnosed and undertreated. The authors attribute this to a public attitude that trivializes allergic conditions, along with patients' general dissatisfaction with the conventional pharmacy-based ways of treating allergic conditions. They conclude that the extensive implementation of SLIT treatment in Europe has proven to overcome these shortcomings in reaching patients, and the treatment is supported with significant literature documenting its efficacy, along with extensive clinical experience.

In a response to the invited article, AAO-HNSF Board of Directors member John H. Krouse, MD, PhD, recognizes the promising data associated with SLIT treatment, but urges caution until several issues can be addressed. Specifically, Dr. Krouse offers five areas of concern with SLIT treatment: patient selection; pattern of sensitization; dosing, preparation, and delivery; safety; and the financial cost of therapy. He concludes by noting the existence of a gap in allergy management in the United States, and the promise SLIT treatment holds, if carefully evaluated, in reaching these unaddressed segments of the population.

Allergy symptoms appear when the immune system reacts to an allergic substance that enters the body as though it is an unwelcomed invader. The immune system will produce special antibodies capable of recognizing the same allergen if it enters the body at a later time.

When an allergen reenters the body, the immune system rapidly recognizes it, causing a series of reactions. These reactions often involve tissue destruction, blood vessel dilation, and production of many inflammatory substances, including histamine. Histamine produces common allergy symptoms such as itchy, watery eyes, nasal and sinus congestion, headaches, sneezing, scratchy throat, hives, and shortness of breath, among others. Other less common symptoms are balance disturbances, skin irritations such as eczema, and even respiratory problems like asthma.

The invited article's authors are Ivor A. Emanuel, MD, of University of California-San Francisco, and Stanford University; Michael J. Parker, MD, of SUNY Upstate Medical University in Syracuse, NY; and Oren Traub, MD, PhD, of Seattle, WA. The corresponding response was authored by John H. Krouse, MD, PhD, of Wayne State University in Detroit, MI.


Story Source:

The above story is based on materials provided by American Academy of Otolaryngology -- Head and Neck Surgery. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Otolaryngology -- Head and Neck Surgery. "Sublingual Immunotherapy For Inhalant Allergies Deserves Deeper Consideration, Experts Urge." ScienceDaily. ScienceDaily, 6 May 2009. <www.sciencedaily.com/releases/2009/04/090429120853.htm>.
American Academy of Otolaryngology -- Head and Neck Surgery. (2009, May 6). Sublingual Immunotherapy For Inhalant Allergies Deserves Deeper Consideration, Experts Urge. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2009/04/090429120853.htm
American Academy of Otolaryngology -- Head and Neck Surgery. "Sublingual Immunotherapy For Inhalant Allergies Deserves Deeper Consideration, Experts Urge." ScienceDaily. www.sciencedaily.com/releases/2009/04/090429120853.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com
Winter Can Cause Depression — Here's How To Combat It

Winter Can Cause Depression — Here's How To Combat It

Newsy (Nov. 23, 2014) Millions of American suffer from seasonal depression every year. It can lead to adverse health effects, but there are ways to ease symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins