Featured Research

from universities, journals, and other organizations

Formaldehyde Exposure Associated With Risk Of Blood And Lymph System Malignancies

Date:
May 14, 2009
Source:
Journal of the National Cancer Institute
Summary:
Individuals exposed to relatively higher amounts of formaldehyde had a higher rate of death due to blood and lymph system malignancies than those exposed to lower levels of formaldehyde in a large cohort study.

Individuals exposed to relatively higher amounts of formaldehyde had a higher rate of death due to blood and lymph system malignancies than those exposed to lower levels of formaldehyde in a large cohort study.

Related Articles


In the National Cancer Institute's formaldehyde cohort, which was previously followed through 1994, formaldehyde exposure was associated with an increased risk of leukemia. In the current study, Laura Beane Freeman, Ph.D., of the NCI in Rockville, Md., and colleagues, extended the follow-up through 2004. The cohort includes 25,619 individuals exposed to formaldehyde at work.

With a median follow-up of 42 years, the investigators observed a positive association between all lymphohematopoietic malignancies and peak formaldehyde exposure, with a 1.37-fold higher risk among those with the highest peak exposures compared with those with the lowest level of peak exposures. There was no statistically significant association with cumulative exposure or average intensity of exposure. An excess risk was seen for several sub-types of these malignancies, most notably myeloid leukemia, with a 1.78-fold higher risk. Myeloid leukemia is the type most often associated with chemical exposures. The level of increased risk was highest earlier in the follow-up period and then declined steadily over time such that the cumulative excess risk no longer reached statistical significance.

"In the current follow-up, the overall risk of myeloid leukemia has declined from our previous report, but remains somewhat elevated. While that time trend may suggest that the previous excess risk estimates were due to chance, the pattern is consistent with a possible causal association, with the largest risks occurring closer in time to relevant exposure," the authors write. "It is our opinion that the overall pattern of risks seen in this extended follow-up of formaldehyde workers, while not definitive, warrants continued concern."

This research was published in the Journal of the National Cancer Institute May 12, 2009.


Story Source:

The above story is based on materials provided by Journal of the National Cancer Institute. Note: Materials may be edited for content and length.


Cite This Page:

Journal of the National Cancer Institute. "Formaldehyde Exposure Associated With Risk Of Blood And Lymph System Malignancies." ScienceDaily. ScienceDaily, 14 May 2009. <www.sciencedaily.com/releases/2009/05/090512192912.htm>.
Journal of the National Cancer Institute. (2009, May 14). Formaldehyde Exposure Associated With Risk Of Blood And Lymph System Malignancies. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2009/05/090512192912.htm
Journal of the National Cancer Institute. "Formaldehyde Exposure Associated With Risk Of Blood And Lymph System Malignancies." ScienceDaily. www.sciencedaily.com/releases/2009/05/090512192912.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Reuters - Innovations Video Online (Dec. 21, 2014) A team of scientists led by Danish chemist Jorn Christensen says they have isolated two chemical compounds within an existing antipsychotic medication that could be used to help a range of failing antibiotics work against killer bacterial infections, such as Tuberculosis. Jim Drury went to meet him. Video provided by Reuters
Powered by NewsLook.com
Hugging It Out Could Help You Ward Off A Cold

Hugging It Out Could Help You Ward Off A Cold

Newsy (Dec. 21, 2014) Carnegie Mellon researchers found frequent hugs can help people avoid stress-related illnesses. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins