Featured Research

from universities, journals, and other organizations

Study Calls For 'As Soon As Possible' Treatment Standard For Heart Attack Patients

Date:
May 25, 2009
Source:
BMJ-British Medical Journal
Summary:
Once in hospital, heart attack patients should be treated without delay to cut their risk of death, ideally within even less than the 90 minutes currently recommended by clinical guidelines, say researchers.

Once in hospital, heart attack patients should be treated without delay to cut their risk of death, ideally within even less than the 90 minutes currently recommended by clinical guidelines, say researchers in a paper published on the British Medical Journal website.

Related Articles


After a heart attack, patients often undergo a procedure using a balloon-tipped catheter that is inserted into a main artery, pushed into the narrowed coronary artery, and inflated to clear the blockage. This is called primary percutaneous coronary intervention, or more simply balloon angioplasty.

The time between a patient's arrival at hospital and first balloon inflation is known as the "door-to-balloon time." The current target is 90 minutes, but the benefits of reducing this time even further is still unclear.

So researchers based in the United States set out to investigate the association between door-to-balloon time and deaths in hospital among patients undergoing balloon angioplasty after a heart attack.

They analysed data for 43,801 patients from the American College of Cardiology National Cardiovascular Data Registry. All patients underwent balloon angioplasty within 12 hours of a heart attack at a United States acute care hospital between 2005 and 2006.

Average door-to-balloon time was 83 minutes, with over half of patients (58%) treated within 90 minutes of admission. Overall in-hospital mortality was 4.6%. A greater proportion of patients who had longer door-to-balloon times were women, non-white, and, on average, older than patients with shorter door-to-balloon times. They also had more comorbidities (other disorders, such as diabetes and high blood pressure) than patients with shorter door-to-balloon times.

After adjusting for factors that may have affected the results, longer door-to-balloon times were associated with a higher risk of in-hospital mortality. For example, 3% of patients with door-to-balloon times of 30 minutes died in hospital, while 4.3% of patients with door-to-balloon times of 90 minutes died. The highest mortality rate (10.3%) was for patients with door-to-balloon times of 270 minutes.

These results indicate that any delay in door-to-balloon time for heart attack patients undergoing balloon angioplasty is associated with higher mortality, even among patients treated within 90 minutes of admission, say the authors.

"Rather than accepting the 90 minute door-to-balloon time benchmark, our data support calls for an 'as soon as possible' standard for patients undergoing primary percutaneous coronary intervention. Such an approach, using necessary safeguards against inappropriate treatment, offers the potential for notable mortality reduction," they conclude.


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Cite This Page:

BMJ-British Medical Journal. "Study Calls For 'As Soon As Possible' Treatment Standard For Heart Attack Patients." ScienceDaily. ScienceDaily, 25 May 2009. <www.sciencedaily.com/releases/2009/05/090519214948.htm>.
BMJ-British Medical Journal. (2009, May 25). Study Calls For 'As Soon As Possible' Treatment Standard For Heart Attack Patients. ScienceDaily. Retrieved February 28, 2015 from www.sciencedaily.com/releases/2009/05/090519214948.htm
BMJ-British Medical Journal. "Study Calls For 'As Soon As Possible' Treatment Standard For Heart Attack Patients." ScienceDaily. www.sciencedaily.com/releases/2009/05/090519214948.htm (accessed February 28, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, February 28, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Reuters - Innovations Video Online (Feb. 27, 2015) A dongle that plugs into a Smartphone mimics a lab-based blood test for HIV and syphilis and can detect the diseases in 15 minutes, say researchers. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Doctor Says Head Transplants Possible Within Two Years

Doctor Says Head Transplants Possible Within Two Years

Buzz60 (Feb. 27, 2015) An Italian doctor is saying he could stick someone&apos;s head onto someone else&apos;s body. Patrick Jones (@Patrick_E_Jones) reports. Video provided by Buzz60
Powered by NewsLook.com
How Your Dentist Could Help Screen You For Diabetes

How Your Dentist Could Help Screen You For Diabetes

Newsy (Feb. 27, 2015) A new study from researchers at New York University suggests dentists could soon use blood samples taken from patients&apos; mouths to test for diabetes. Video provided by Newsy
Powered by NewsLook.com
The Best Tips to Makeover Your Health

The Best Tips to Makeover Your Health

Buzz60 (Feb. 27, 2015) If you&apos;re looking to boost your health this season, there are a few quick and easy steps to prompt you for success. Krystin Goodwin (@Krystingoodwin) has the best tips to give your health a makeover this spring! Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins