Featured Research

from universities, journals, and other organizations

Immunomagnetic Beads Can Attract Plague Bacteria

Date:
May 25, 2009
Source:
USDA/Agricultural Research Service
Summary:
Scientists have used antibody-coated immunomagnetic beads (IMBs) to detect the bacterium that causes bubonic plague.

ARS microbiologist George Paoli and his colleagues have developed antibody-coated immunomagnetic beads that can detect Yersinia pestis, the bacterium that causes bubonic plague.
Credit: Photo by Paul Pierlott

Agricultural Research Service (ARS) scientists have used antibody-coated immunomagnetic beads (IMBs) to detect Yersinia pestis, the bacterium that causes bubonic plague.

While similar techniques are often used to detect various bacterial species, the methods must be altered to suit specific pathogens. This is done by taking advantage of variations in the biological makeup of the different bacteria. Because antibodies can be selected that bind to very specific targets, antibody-coated IMBs can be used to specifically remove target pathogens from the other harmless bacteria present in most food.

The trick to IMB technology is finding an antibody that attaches to one, and only one, target--for example, a Y. pestis antigen. At the ARS Eastern Regional Research Center in Wyndmoor, Pa., microbiologist George Paoli and his colleagues have developed IMBs to capture Y. pestis. In preliminary tests with milk samples, the technology has been successful.

The team is also using genetic methods that rely on a common DNA test known as the "polymerase chain reaction," or PCR. The group has developed PCR-based methods to detect Y. pestis and differentiate it from other foodborne bacteria, including two closely related Yersinia species, Y. enterocolitica and Y. pseudotuberculosis.

They have also developed a PCR method that targets genes related to the virulence of Y. pestis. This test could be used to determine the virulence of a particular strain of the pathogen and estimate its potential public health impact.

The scientists are currently working to combine the different areas of this research to develop a complete set of tools for the detection of Y. pestis in food, as part of a holistic approach to food security.

Research efforts like these ensure that U.S. consumers and food industry professionals have the most advanced technology and information available to protect them from potential pathogen threats.


Story Source:

The above story is based on materials provided by USDA/Agricultural Research Service. Note: Materials may be edited for content and length.


Cite This Page:

USDA/Agricultural Research Service. "Immunomagnetic Beads Can Attract Plague Bacteria." ScienceDaily. ScienceDaily, 25 May 2009. <www.sciencedaily.com/releases/2009/05/090522181804.htm>.
USDA/Agricultural Research Service. (2009, May 25). Immunomagnetic Beads Can Attract Plague Bacteria. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2009/05/090522181804.htm
USDA/Agricultural Research Service. "Immunomagnetic Beads Can Attract Plague Bacteria." ScienceDaily. www.sciencedaily.com/releases/2009/05/090522181804.htm (accessed April 18, 2014).

Share This



More Plants & Animals News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Vermont Goat Meat Gives Refugees Taste of Home

Vermont Goat Meat Gives Refugees Taste of Home

AP (Apr. 18, 2014) Dairy farmers and ethnic groups in Vermont are both benefiting from a unique collaborative effort that's feeding a growing need for fresh and affordable goat meat. (April 18) Video provided by AP
Powered by NewsLook.com
The Great British Farmland Boom

The Great British Farmland Boom

Reuters - Business Video Online (Apr. 17, 2014) Britain's troubled Co-operative Group is preparing to cash in on nearly 18,000 acres of farmland in one of the biggest UK land sales in decades. As Ivor Bennett reports, the market timing couldn't be better, with farmland prices soaring over 270 percent in the last 10 years. Video provided by Reuters
Powered by NewsLook.com
Flamingo Frenzy Ahead of Zoo Construction

Flamingo Frenzy Ahead of Zoo Construction

AP (Apr. 17, 2014) With plenty of honking, flapping, and fluttering, more than three dozen Caribbean flamingos at Zoo Miami were rounded up today as the iconic exhibit was closed for renovations. (April 17) Video provided by AP
Powered by NewsLook.com
Change of Diet Helps Crocodile Business

Change of Diet Helps Crocodile Business

Reuters - Business Video Online (Apr. 16, 2014) Crocodile farming has been a challenge in Zimbabwe in recent years do the economic collapse and the financial crisis. But as Ciara Sutton reports one of Europe's biggest suppliers of skins to the luxury market has come up with an unusual survival strategy - vegetarian food. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins