Featured Research

from universities, journals, and other organizations

Immunomagnetic Beads Can Attract Plague Bacteria

Date:
May 25, 2009
Source:
USDA/Agricultural Research Service
Summary:
Scientists have used antibody-coated immunomagnetic beads (IMBs) to detect the bacterium that causes bubonic plague.

ARS microbiologist George Paoli and his colleagues have developed antibody-coated immunomagnetic beads that can detect Yersinia pestis, the bacterium that causes bubonic plague.
Credit: Photo by Paul Pierlott

Agricultural Research Service (ARS) scientists have used antibody-coated immunomagnetic beads (IMBs) to detect Yersinia pestis, the bacterium that causes bubonic plague.

While similar techniques are often used to detect various bacterial species, the methods must be altered to suit specific pathogens. This is done by taking advantage of variations in the biological makeup of the different bacteria. Because antibodies can be selected that bind to very specific targets, antibody-coated IMBs can be used to specifically remove target pathogens from the other harmless bacteria present in most food.

The trick to IMB technology is finding an antibody that attaches to one, and only one, target--for example, a Y. pestis antigen. At the ARS Eastern Regional Research Center in Wyndmoor, Pa., microbiologist George Paoli and his colleagues have developed IMBs to capture Y. pestis. In preliminary tests with milk samples, the technology has been successful.

The team is also using genetic methods that rely on a common DNA test known as the "polymerase chain reaction," or PCR. The group has developed PCR-based methods to detect Y. pestis and differentiate it from other foodborne bacteria, including two closely related Yersinia species, Y. enterocolitica and Y. pseudotuberculosis.

They have also developed a PCR method that targets genes related to the virulence of Y. pestis. This test could be used to determine the virulence of a particular strain of the pathogen and estimate its potential public health impact.

The scientists are currently working to combine the different areas of this research to develop a complete set of tools for the detection of Y. pestis in food, as part of a holistic approach to food security.

Research efforts like these ensure that U.S. consumers and food industry professionals have the most advanced technology and information available to protect them from potential pathogen threats.


Story Source:

The above story is based on materials provided by USDA/Agricultural Research Service. Note: Materials may be edited for content and length.


Cite This Page:

USDA/Agricultural Research Service. "Immunomagnetic Beads Can Attract Plague Bacteria." ScienceDaily. ScienceDaily, 25 May 2009. <www.sciencedaily.com/releases/2009/05/090522181804.htm>.
USDA/Agricultural Research Service. (2009, May 25). Immunomagnetic Beads Can Attract Plague Bacteria. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2009/05/090522181804.htm
USDA/Agricultural Research Service. "Immunomagnetic Beads Can Attract Plague Bacteria." ScienceDaily. www.sciencedaily.com/releases/2009/05/090522181804.htm (accessed October 20, 2014).

Share This



More Plants & Animals News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

White Lion Cubs Born in Belgrade Zoo

White Lion Cubs Born in Belgrade Zoo

AFP (Oct. 20, 2014) Two white lion cubs, an extremely rare subspecies of the African lion, were recently born at Belgrade Zoo. They are being bottle fed by zoo keepers after they were rejected by their mother after birth. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Traditional Farming Methods Gaining Ground in Mali

Traditional Farming Methods Gaining Ground in Mali

AFP (Oct. 20, 2014) He is leading a one man agricultural revolution in Mali - Oumar Diatabe uses traditional farming methods to get the most out of his land and is teaching others across the country how to do the same. Duration: 01:44 Video provided by AFP
Powered by NewsLook.com
Goliath Spider Will Give You Nightmares

Goliath Spider Will Give You Nightmares

Buzz60 (Oct. 20, 2014) An entomologist stumbled upon a South American Goliath Birdeater. With a name like that, you know it's a terrifying creepy crawler. Sean Dowling (@SeanDowlingTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Hey, Doc! Sewage, Beer and Food Scraps Can Power Chevrolet’s Bi-Fuel Impala

Hey, Doc! Sewage, Beer and Food Scraps Can Power Chevrolet’s Bi-Fuel Impala

3BL Media (Oct. 20, 2014) Hey, Doc! Sewage, Beer and Food Scraps Can Power Chevrolet’s Bi-fuel Impala Video provided by 3BL
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins