Featured Research

from universities, journals, and other organizations

Toward An 'Electronic Nose' To Sniff Out Kidney Disease In Exhaled Breath

Date:
June 19, 2009
Source:
American Chemical Society
Summary:
Scientists have identified the key substances in exhaled breath associated with healthy and diseased kidneys — raising expectations, they say, for development of long-sought diagnostic and screening tests that literally sniff out chronic renal failure (CRF) in its earliest and most treatable stages.

Scientists report advances toward an "electronic nose" that could detect kidney disease.
Credit: The American Chemical Society

Scientists in Israel have identified the key substances in exhaled breath associated with healthy and diseased kidneys — raising expectations, they say, for development of long-sought diagnostic and screening tests that literally sniff out chronic renal failure (CRF) in its earliest and most treatable stages.

In the new study, Hossam Haick and colleagues point out that the blood and urine tests now used to diagnose CRF can be inaccurate and may come out "normal" even when patients have lost 75 percent of their kidney function. The most reliable test, a kidney biopsy, is invasive and may result in infections and bleeding. Doctors have long hoped for better tests for early detection of kidney disease.

The scientists describe tests of an experimental "electronic nose" on exhaled breath of laboratory rats with no kidney function and normal kidney function. The device identified 27 so-called volatile organic compounds that appear only in the breath of rats with CRF.

The results presented in this study "raise expectations for future capabilities for diagnosis, detection, and screening various stages of kidney disease," they said, noting that the tests could detect patients with early disease who could be treated in ways that could slow its progression.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Haick et al. Sniffing Chronic Renal Failure in Rat Model by an Array of Random Networks of Single-Walled Carbon Nanotubes. ACS Nano, 2009; 3 (5): 1258 DOI: 10.1021/nn9001775

Cite This Page:

American Chemical Society. "Toward An 'Electronic Nose' To Sniff Out Kidney Disease In Exhaled Breath." ScienceDaily. ScienceDaily, 19 June 2009. <www.sciencedaily.com/releases/2009/06/090615100053.htm>.
American Chemical Society. (2009, June 19). Toward An 'Electronic Nose' To Sniff Out Kidney Disease In Exhaled Breath. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2009/06/090615100053.htm
American Chemical Society. "Toward An 'Electronic Nose' To Sniff Out Kidney Disease In Exhaled Breath." ScienceDaily. www.sciencedaily.com/releases/2009/06/090615100053.htm (accessed July 30, 2014).

Share This




More Health & Medicine News

Wednesday, July 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Generics Eat Into Pfizer's Sales

Generics Eat Into Pfizer's Sales

Reuters - Business Video Online (July 29, 2014) Pfizer, the world's largest drug maker, cut full-year revenue forecasts because generics could cut into sales of its anti-arthritis drug, Celebrex. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins