Featured Research

from universities, journals, and other organizations

Sleep Apnea Occurring During REM Sleep Is Significantly Associated With Type 2 Diabetes

Date:
June 24, 2009
Source:
American Academy of Sleep Medicine
Summary:
Scientists found a statistically significant relationship between obstructive sleep apnea episodes occurring during rapid eye movement (REM) sleep and type 2 diabetes.

A multi-ethnic study in the June 15 issue of the Journal of Clinical Sleep Medicine reports that there is a statistically significant relationship between obstructive sleep apnea (OSA) episodes occurring during rapid eye movement (REM) sleep and type 2 diabetes.

Related Articles


Results indicate that the adjusted odds ratio for type 2 diabetes was 2.0 times higher in patients with REM-related OSA, defined as havng an REM apnea-hypopnea index (AHI) of 10 or more breathing pauses per hour of REM sleep. The prevalence of type 2 diabetes was 30.1 percent in participants with OSA and 18.6 percent in those without OSA; however, the overall association between OSA and diabetes became non-significant after controlling for covariates such as body mass index (BMI), age, race and gender. Middle-aged participants with OSA had an adjusted odds ratio for type 2 diabetes that was 2.8 times higher than younger or middle-aged people without OSA. Hispanics and older patients referred for OSA evaluation had a higher prevalence of type 2 diabetes; this relationship was not affected by OSA.

According to principle investigator Kamran Mahmood, MD, MPH, of the University of Illinois at Chicago, the researchers were surprised by the significant association of REM-related OSA with type 2 diabetes.

"We believe that REM-related OSA is a marker of early OSA, especially in women and patients younger than 55 years," said Mahmood. "Generally, OSA is worse in REM sleep compared to non-REM sleep because of neurologically mediated impairment of skeletal muscles of upper airway and ventilation. This may be the reason for closer association of REM-related OSA and type 2 diabetes."

The study gathered data from 1,008 consecutive patients who were evaluated for OSA by comprehensive polysomnography at the University of Illinois at Chicago; 66.9 percent were African American, 16.9 percent were Caucasian, 14.9 percent were Hispanic and 1.3 percent were Asian. OSA was defined as an AHI of five or more breathing pauses per hour of sleep and was diagnosed in 745 individuals (74 percent); the 263 adults (26 percent) who did not have OSA served as the control. Men comprised 52.8 percent of the OSA group but only 28.5 percent of the control group.

According to the authors, the findings are consistent with several studies on the association of OSA with glucose tolerance, insulin resistance and type 2 diabetes. REM-related OSA is more common in mild-to-moderate cases of OSA, especially in women and in patients younger than 55 years of age. Sleep fragmentation caused by OSA may reduce REM sleep time, which could explain a high REM AHI.

Mahmood said that the results highlight the need to educate minority groups about OSA and its complications. The authors encourage awareness campaigns and making OSA screening part of all obesity management programs.

According to the American Academy of Sleep Medicine, OSA is a sleep-related breathing disorder that involves a decrease or complete halt in airflow despite an ongoing effort to breathe. It occurs when the muscles relax during sleep, causing soft tissue in the back of the throat to collapse and block the upper airway. This leads to partial reductions (hypopneas) and complete pauses (apneas) in breathing that can produce abrupt reductions in blood oxygen saturation. Brief arousals from sleep restore normal breathing but can cause a fragmented quality of sleep. Most people with OSA snore loudly and frequently, and they often experience excessive daytime sleepiness.


Story Source:

The above story is based on materials provided by American Academy of Sleep Medicine. Note: Materials may be edited for content and length.


Journal Reference:

  1. Prevalence of Type 2 Diabetes in Patients with Obstructive Sleep Apnea in a Multi-Ethnic Sample. Journal of Clinical Sleep Medicine, June 15, 2009

Cite This Page:

American Academy of Sleep Medicine. "Sleep Apnea Occurring During REM Sleep Is Significantly Associated With Type 2 Diabetes." ScienceDaily. ScienceDaily, 24 June 2009. <www.sciencedaily.com/releases/2009/06/090615112229.htm>.
American Academy of Sleep Medicine. (2009, June 24). Sleep Apnea Occurring During REM Sleep Is Significantly Associated With Type 2 Diabetes. ScienceDaily. Retrieved March 31, 2015 from www.sciencedaily.com/releases/2009/06/090615112229.htm
American Academy of Sleep Medicine. "Sleep Apnea Occurring During REM Sleep Is Significantly Associated With Type 2 Diabetes." ScienceDaily. www.sciencedaily.com/releases/2009/06/090615112229.htm (accessed March 31, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, March 31, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Solitair Device Aims to Takes Guesswork out of Sun Safety

Solitair Device Aims to Takes Guesswork out of Sun Safety

Reuters - Innovations Video Online (Mar. 31, 2015) — The Solitair device aims to take the confusion out of how much sunlight we should expose our skin to. Small enough to be worn as a tie or hair clip, it monitors the user&apos;s sun exposure by taking into account their skin pigment, location and schedule. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Soda, Salt and Sugar: The Next Generation of Taxes

Soda, Salt and Sugar: The Next Generation of Taxes

Washington Post (Mar. 30, 2015) — Denisa Livingston, a health advocate for the Dinι Community Advocacy Alliance, and the Post&apos;s Abby Phillip discuss efforts around the country to make unhealthy food choices hurt your wallet as much as your waistline. Video provided by Washington Post
Powered by NewsLook.com
UnitedHealth Buys Catamaran

UnitedHealth Buys Catamaran

Reuters - Business Video Online (Mar. 30, 2015) — The $12.8 billion merger will combine the U.S.&apos; third and fourth largest pharmacy benefit managers. Analysts say smaller PBMs could also merge. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) — Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins