Featured Research

from universities, journals, and other organizations

Tiny Levels Of Carbon Monoxide Damage Fetal Brain

Date:
June 26, 2009
Source:
University of California - Los Angeles
Summary:
A new study has discovered that chronic exposure during pregnancy to minuscule levels of carbon monoxide damages the cells of the fetal brain, resulting in permanent impairment.

A UCLA study has discovered that chronic exposure during pregnancy to miniscule levels of carbon monoxide damages the cells of the fetal brain, resulting in permanent impairment. The journal BMC Neuroscience published the findings June 22 in its online edition.

"We expected the placenta to protect fetuses from the mother's exposure to tiny amounts of carbon monoxide," said John Edmond, professor emeritus of biological chemistry at the David Geffen School of Medicine at UCLA. "But we found that not to be the case."

The researchers exposed pregnant rats to 25 parts per million carbon monoxide in the air, an exposure level established as safe by Cal/OSHA, California's division of occupational health and safety.

Dr. Ivan Lopez, UCLA associate professor of head and neck surgery, tested the rats' litters 20 days after birth. Rats born to animals who had inhaled the gas suffered chronic oxidative stress, a harmful condition caused by an excess of harmful free radicals or insufficient antioxidants.

"Oxidative stress damaged the baby rats' brain cells, leading to a drop in proteins essential for proper function," said Lopez. "Oxidative stress is a risk factor linked to many disorders, including autism, cancer, Alzheimer's, Parkinson's, Lou Gehrig's disease, multiple sclerosis and cardiovascular disease. We know that it exacerbates disease."

"We believe that the minute levels of carbon monoxide in the mother rats' environment made their offspring more vulnerable to illness," added Edmond. "Our findings highlight the need for policy makers to re-examine the regulation of carbon monoxide."

Tobacco smoke, gas heaters, stoves and ovens all emit carbon monoxide, which can rise to high concentrations in well-insulated homes. Infants and children are particularly vulnerable to carbon monoxide exposure because they spend a great deal of time in the home.

No policies exist to regulate the gas in the home. Most commercial home monitors sound an alarm only hours after concentrations reaches 70 parts per million--nearly three times the 25 parts per million limit set by Cal/OSHA.

A grant from the University of California's Tobacco-related Disease Research Program supported the research.


Story Source:

The above story is based on materials provided by University of California - Los Angeles. Note: Materials may be edited for content and length.


Cite This Page:

University of California - Los Angeles. "Tiny Levels Of Carbon Monoxide Damage Fetal Brain." ScienceDaily. ScienceDaily, 26 June 2009. <www.sciencedaily.com/releases/2009/06/090625100625.htm>.
University of California - Los Angeles. (2009, June 26). Tiny Levels Of Carbon Monoxide Damage Fetal Brain. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2009/06/090625100625.htm
University of California - Los Angeles. "Tiny Levels Of Carbon Monoxide Damage Fetal Brain." ScienceDaily. www.sciencedaily.com/releases/2009/06/090625100625.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins