Featured Research

from universities, journals, and other organizations

Integrated Optical Trap Holds Particles For On-chip Analysis

Date:
July 6, 2009
Source:
University of California - Santa Cruz
Summary:
A new type of optical particle trap can be used to manipulate bacteria, viruses and other particles on a chip as part of an integrated optofluidic platform.

The integrated optical trap allows independent manipulation of trapped microbeads as shown in this view of two microbeads trapped by two different dual-beam traps.
Credit: Image courtesy of H. Schmidt

A new type of optical particle trap can be used to manipulate bacteria, viruses and other particles on a chip as part of an integrated optofluidic platform. The optical trap is the latest innovation from researchers at the Jack Baskin School of Engineering at the University of California, Santa Cruz, who are developing new sensor technology for biomedical analysis and other applications.

Related Articles


"Ultimately, it could have applications for rapid detection of bacteria and viruses in hospitals, for cell sorting in research labs, and for process monitoring in chemical engineering," said Holger Schmidt, professor of electrical engineering and director of the W. M. Keck Center for Nanoscale Optofluidics at UCSC.

The new technique offers the potential to create a smaller, cheaper version of the sophisticated equipment used to perform fluorescence-activated cell sorting (FACS), Schmidt said.

"The capabilities of our optofluidic platform are continuing to grow. We have gone from the detection of single molecules and single viruses to now being able to control the movement of particles," he said.

Schmidt's group has received a $400,000 grant from the National Institutes of Health to explore particle trapping and sorting and other applications of the optofluidics platform. An article describing the optical trap for on-chip particle analysis has been published online by the journal Lab on a Chip. First author Sergei Kuhn was a postdoctoral researcher in Schmidt's lab and is now at the Max-Born Institute in Berlin. Coauthors include David Deamer and Philip Measor at UCSC and E. J. Lunt, B. S. Phillips, and A. R. Hawkins of Brigham Young University, where the optofluidic chips are fabricated.

Optical traps and "optical tweezers" use the momentum carried by the photons in a beam of light to exert forces on microscopic objects, enabling researchers to manipulate objects ranging from biological molecules to living cells. Schmidt's group developed a new way to perform optical trapping on a chip-based platform.

The technique relies on an earlier innovation from Schmidt's lab: a hollow-core optical waveguide that can direct a beam of light through a liquid-filled channel on a chip. To trap particles, the researchers used two laser beams at opposite ends of a channel. A particle gets trapped at the point where the forces exerted by the two beams are equal, and the particle can be moved by changing the relative power of the two laser beams.

"We can also use this like an optical leaf blower to push all the particles in a sample to the same spot and increase the concentration," Schmidt said. "The goal is to control the position and movement of particles through channels on a chip so they can be studied using fluorescence analysis and other optical methods."


Story Source:

The above story is based on materials provided by University of California - Santa Cruz. Note: Materials may be edited for content and length.


Cite This Page:

University of California - Santa Cruz. "Integrated Optical Trap Holds Particles For On-chip Analysis." ScienceDaily. ScienceDaily, 6 July 2009. <www.sciencedaily.com/releases/2009/07/090702170126.htm>.
University of California - Santa Cruz. (2009, July 6). Integrated Optical Trap Holds Particles For On-chip Analysis. ScienceDaily. Retrieved November 25, 2014 from www.sciencedaily.com/releases/2009/07/090702170126.htm
University of California - Santa Cruz. "Integrated Optical Trap Holds Particles For On-chip Analysis." ScienceDaily. www.sciencedaily.com/releases/2009/07/090702170126.htm (accessed November 25, 2014).

Share This


More From ScienceDaily



More Matter & Energy News

Tuesday, November 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Who Will Failed Nuclear Talks Hurt Most?

Who Will Failed Nuclear Talks Hurt Most?

Reuters - Business Video Online (Nov. 25, 2014) With no immediate prospect of sanctions relief for Iran, and no solid progress in negotiations with the West over the country's nuclear programme, Ciara Lee asks why talks have still not produced results and what a resolution would mean for both parties. Video provided by Reuters
Powered by NewsLook.com
Flying Enthusiast Converts Real-Life Aircraft Cockpit Into Simulator

Flying Enthusiast Converts Real-Life Aircraft Cockpit Into Simulator

Reuters - Innovations Video Online (Nov. 25, 2014) A virtual flying enthusiast converts parts of a written-off Airbus aircraft into a working flight simulator in his northern Slovenian home. Jim Drury reports. Video provided by Reuters
Powered by NewsLook.com
Car Park Solution for Flexible Green Energy

Car Park Solution for Flexible Green Energy

Reuters - Innovations Video Online (Nov. 24, 2014) A British solar power start-up says that by covering millions of existing car park spaces around the UK with flexible solar panels, the country's power problems could be solved. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Microsoft Adds Robot Guards, Ushers In Sci-Fi Apocalypse

Microsoft Adds Robot Guards, Ushers In Sci-Fi Apocalypse

Newsy (Nov. 23, 2014) Microsoft has robotic security guards working at its Silicon Valley Campus. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins