Featured Research

from universities, journals, and other organizations

Pharmacy Research Shows Prescribers Miss Potentially Dangerous Drug Pairs

Date:
July 16, 2009
Source:
University of Arizona, College of Pharmacy
Summary:
Medication prescribers correctly identified fewer than half of drug pairs with potentially dangerous drug-drug interactions. The researchers mailed a questionnaire to 12,500 U.S. prescribers who were selected based on a history of prescribing drugs associated with known potential for drug-drug interaction. Prescribers were primarily physicians, physicians' assistants and nurse practitioners.

Research led by The University of Arizona College of Pharmacy has found that medication prescribers correctly identified fewer than half of drug pairs with potentially dangerous drug-drug interactions.

These findings raise concern because of the high number of drugs Americans take: an average of 2.3 medications is prescribed during each physician office visit.

A synopsis of the research was published in May Research Activities, a digest of research findings intended to contribute to the national policymaking process.

The researchers, led by Daniel Malone, PhD, professor at the UA College of Pharmacy, mailed a questionnaire to 12,500 U.S. prescribers who were selected based on a history of prescribing drugs associated with known potential for drug-drug interaction. Prescribers were primarily physicians, physicians’ assistants and nurse practitioners.

Recipients were asked to classify 14 drug pairs as “contraindicated,” “may be used together but with monitoring” or “no interaction.” Respondents could also state that they were “not sure.”

For the drug pairs, one commonly prescribed medication was matched with another commonly prescribed medication.

The 950 respondents classified 42.7 percent of all drug combinations correctly.

Of the 14 drug pairs presented, four of them were contraindicated, meaning they should not be used together. A majority of prescribers correctly identified only one of the four pairs as contraindicated.

Moreover, for half of the 14 drug pairs, more than one-third of the respondents answered that they were “not sure,” and two of these drug pairs were contraindicated.

“The study found a very low rate of recognition of these particular interactions,” says Malone, “and some of these interactions are very common.”

Use of several of the contraindicated drug pairs could be dangerous. For example, taking sildenafil (Viagraฎ) and nitrates, such as isosorbide mononitrate, can be life-threatening.

According to Malone, the research indicates that health professional programs are not doing enough to teach students about potential drug-drug interactions. Consequently, patients should be sure to tell their pharmacist of all the medications they are taking.


Story Source:

The above story is based on materials provided by University of Arizona, College of Pharmacy. Note: Materials may be edited for content and length.


Cite This Page:

University of Arizona, College of Pharmacy. "Pharmacy Research Shows Prescribers Miss Potentially Dangerous Drug Pairs." ScienceDaily. ScienceDaily, 16 July 2009. <www.sciencedaily.com/releases/2009/07/090713160518.htm>.
University of Arizona, College of Pharmacy. (2009, July 16). Pharmacy Research Shows Prescribers Miss Potentially Dangerous Drug Pairs. ScienceDaily. Retrieved August 30, 2014 from www.sciencedaily.com/releases/2009/07/090713160518.htm
University of Arizona, College of Pharmacy. "Pharmacy Research Shows Prescribers Miss Potentially Dangerous Drug Pairs." ScienceDaily. www.sciencedaily.com/releases/2009/07/090713160518.htm (accessed August 30, 2014).

Share This




More Health & Medicine News

Saturday, August 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

3 Things To Know About The Ebola Outbreak's Progression

3 Things To Know About The Ebola Outbreak's Progression

Newsy (Aug. 29, 2014) — Here are three things you need to know about the deadly Ebola outbreak's progression this week. Video provided by Newsy
Powered by NewsLook.com
Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) — State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) — The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) — CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins