Featured Research

from universities, journals, and other organizations

Pharmacy Research Shows Prescribers Miss Potentially Dangerous Drug Pairs

Date:
July 16, 2009
Source:
University of Arizona, College of Pharmacy
Summary:
Medication prescribers correctly identified fewer than half of drug pairs with potentially dangerous drug-drug interactions. The researchers mailed a questionnaire to 12,500 U.S. prescribers who were selected based on a history of prescribing drugs associated with known potential for drug-drug interaction. Prescribers were primarily physicians, physicians' assistants and nurse practitioners.

Research led by The University of Arizona College of Pharmacy has found that medication prescribers correctly identified fewer than half of drug pairs with potentially dangerous drug-drug interactions.

These findings raise concern because of the high number of drugs Americans take: an average of 2.3 medications is prescribed during each physician office visit.

A synopsis of the research was published in May Research Activities, a digest of research findings intended to contribute to the national policymaking process.

The researchers, led by Daniel Malone, PhD, professor at the UA College of Pharmacy, mailed a questionnaire to 12,500 U.S. prescribers who were selected based on a history of prescribing drugs associated with known potential for drug-drug interaction. Prescribers were primarily physicians, physicians’ assistants and nurse practitioners.

Recipients were asked to classify 14 drug pairs as “contraindicated,” “may be used together but with monitoring” or “no interaction.” Respondents could also state that they were “not sure.”

For the drug pairs, one commonly prescribed medication was matched with another commonly prescribed medication.

The 950 respondents classified 42.7 percent of all drug combinations correctly.

Of the 14 drug pairs presented, four of them were contraindicated, meaning they should not be used together. A majority of prescribers correctly identified only one of the four pairs as contraindicated.

Moreover, for half of the 14 drug pairs, more than one-third of the respondents answered that they were “not sure,” and two of these drug pairs were contraindicated.

“The study found a very low rate of recognition of these particular interactions,” says Malone, “and some of these interactions are very common.”

Use of several of the contraindicated drug pairs could be dangerous. For example, taking sildenafil (Viagraฎ) and nitrates, such as isosorbide mononitrate, can be life-threatening.

According to Malone, the research indicates that health professional programs are not doing enough to teach students about potential drug-drug interactions. Consequently, patients should be sure to tell their pharmacist of all the medications they are taking.


Story Source:

The above story is based on materials provided by University of Arizona, College of Pharmacy. Note: Materials may be edited for content and length.


Cite This Page:

University of Arizona, College of Pharmacy. "Pharmacy Research Shows Prescribers Miss Potentially Dangerous Drug Pairs." ScienceDaily. ScienceDaily, 16 July 2009. <www.sciencedaily.com/releases/2009/07/090713160518.htm>.
University of Arizona, College of Pharmacy. (2009, July 16). Pharmacy Research Shows Prescribers Miss Potentially Dangerous Drug Pairs. ScienceDaily. Retrieved September 20, 2014 from www.sciencedaily.com/releases/2009/07/090713160518.htm
University of Arizona, College of Pharmacy. "Pharmacy Research Shows Prescribers Miss Potentially Dangerous Drug Pairs." ScienceDaily. www.sciencedaily.com/releases/2009/07/090713160518.htm (accessed September 20, 2014).

Share This



More Health & Medicine News

Saturday, September 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) — Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) — A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) — The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) — A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins