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Dopamine-related Activity Of Food Reward Circuits In The Brain And Weight Gain

Date:
July 27, 2009
Source:
Society for the Study of Ingestive Behavior
Summary:
Women who possess genetic modifications associated with low activity of the reward neurotransmitter dopamine in the brain when they imagine eating appetizing foods are more prone to weight gain.

Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB) finds that women who possess genetic modifications associated with low activity of the reward neurotransmitter dopamine in the brain when they imagine eating appetizing foods are more prone to weight gain. 

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Functional Magnetic Resonance Imaging (fMRI) scans of brain activity revealed that women who had lower activity in food reward regions of the brain and who had genetic modifications associated with lower dopamine activity showed the greatest weight gain after one year.  Eric Stice from the Oregon Research Institute says, “These findings provide some of the first prospective evidence that people who experience blunted reward from food may compensate by overeating, increasing risk for unhealthy weight gain.”  

Overconsumption of appetizing foods may occur in an attempt to increase brain reward in less responsive systems. The results of this study highlight the need for further research into the role that neural reward systems play in the development of obesity. “It may be useful for individuals who show low food-related reward to increase their physical activity, which not only promotes activity the same reward circuitry but also reduces unhealthy weight gain from overeating” says Stice.

Lead author: Eric Stice, Oregon Research Institute, Eugene, OR, USA

Co-authors: S. Spoor and C. Bohon, Oregon Research Institute and University of Oregon, C.N. Marti, University of Texas at Austin, USA.


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The above story is based on materials provided by Society for the Study of Ingestive Behavior. Note: Materials may be edited for content and length.


Cite This Page:

Society for the Study of Ingestive Behavior. "Dopamine-related Activity Of Food Reward Circuits In The Brain And Weight Gain." ScienceDaily. ScienceDaily, 27 July 2009. <www.sciencedaily.com/releases/2009/07/090727102030.htm>.
Society for the Study of Ingestive Behavior. (2009, July 27). Dopamine-related Activity Of Food Reward Circuits In The Brain And Weight Gain. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2009/07/090727102030.htm
Society for the Study of Ingestive Behavior. "Dopamine-related Activity Of Food Reward Circuits In The Brain And Weight Gain." ScienceDaily. www.sciencedaily.com/releases/2009/07/090727102030.htm (accessed November 26, 2014).

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