Featured Research

from universities, journals, and other organizations

Night Home Hemodialysis Shown To Be As Good As Transplant In Treating Kidney Failure

Date:
August 25, 2009
Source:
University Health Network
Summary:
For the first time, it has been shown that patients who receive night home hemodialysis live just as long as those who receive kidney transplants from deceased donors.

For the first time, it has been shown that patients who receive night home hemodialysis live just as long as those who receive kidney transplants from deceased donors.

Related Articles


In a study published in the international September issue of Nephrology Dialysis Transplantation, a total of 1,239 patients were followed for up to 12 years. Night home hemodialysis patients were compared to patients who received either a deceased donor kidney transplant or a living donor kidney transplant. The study found that the survival between night home dialysis patients and those who received kidney transplants from deceased donors was comparable, while the survival of the patients who received a transplant from a living kidney donor was better than both the other groups.

These results suggest that night home hemodialysis, an intensive dialysis of six to eight hour sessions for up to seven times a week, may be a "bridge to transplant" or a "suitable alternative" to transplant should a patient be too high risk for a transplant or not be able to get a living or deceased donor as the organ shortage continues. Night home hemodialysis patients were from the Toronto General and Humber River Regional Hospitals, both hospitals together representing the largest and longest established group of such patients world-wide.

"This study allows me to actually answer what my patients have been asking me for over a decade: 'What does night home hemodialysis mean for my life span?' I can now tell them that this specific dialysis option is as good as getting a transplant from a deceased donor," says Dr. Christopher Chan, Medical Director of Home Hemodialysis at Toronto General Hospital, University Health Network, the R. Fraser Elliott Chair in Home Dialysis and Associate Professor, University of Toronto.

Until this study, there has been no long-term data on night home hemodialysis patient survival, or on how this type of treatment compares to transplantation. In the study, night home hemodialysis patients' data was carefully matched with deceased and living donor kidney transplantation mortality data from the U.S. Renal Data System on characteristics such as age, race, diabetic status and duration of treatment with conventional in-centre dialysis prior to treatment.

The proportion of deaths in each group was then measured, with final figures of 14.7% for night home hemodialysis patients; 14.3% for patients with transplants from deceased donors; and 8.5% for patients with transplants from living donors.

These results diverge from the evidence to date that dialysis is inferior to transplantation, pointed out Dr. Chan, adding that there is much benefit to be gained by long, frequent dialysis.

Night home hemodialysis as good as transplant

Florence Tewogbade, 27, has been on home hemodialysis since April 2008, after trying conventional dialysis. "It has changed my life," she said. "I can now work, go to school, look forward to a future and be self-reliant." Florence was on the transplant waiting list in 2004, but her living donor was found to be ineligible.

Florence says that she would have had to wait about 10 years for a kidney from a deceased donor because of her specific risk factors for receiving a transplant. "I always thought that transplant was the only option, so I didn't consider home hemodialysis," she said. "I thought I couldn't do it. But here I am, doing it, and living a normal life."

Other researchers involved in the study include Robert Pauly, University of Alberta Hospital, John Gill and Caren Rose, St. Paul's Hospital, UBC, Reem Asad, TGH, Anne Cherry, UHN, Andreas Pierratos, Humber River Regional Hospital.


Story Source:

The above story is based on materials provided by University Health Network. Note: Materials may be edited for content and length.


Journal Reference:

  1. Pauly et al. Survival among nocturnal home haemodialysis patients compared to kidney transplant recipients. Nephrology Dialysis Transplantation, 2009; 24 (9): 2915 DOI: 10.1093/ndt/gfp295

Cite This Page:

University Health Network. "Night Home Hemodialysis Shown To Be As Good As Transplant In Treating Kidney Failure." ScienceDaily. ScienceDaily, 25 August 2009. <www.sciencedaily.com/releases/2009/08/090820124125.htm>.
University Health Network. (2009, August 25). Night Home Hemodialysis Shown To Be As Good As Transplant In Treating Kidney Failure. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2009/08/090820124125.htm
University Health Network. "Night Home Hemodialysis Shown To Be As Good As Transplant In Treating Kidney Failure." ScienceDaily. www.sciencedaily.com/releases/2009/08/090820124125.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins