Featured Research

from universities, journals, and other organizations

The Anti-diabetic Effects Of Sodium Tungstate Revealed

Date:
August 28, 2009
Source:
BioMed Central
Summary:
The molecular mechanisms of tungstate activity in diabetes have been uncovered. Researchers have identified the pathways through which sodium tungstate improves pancreatic function and beta cell proliferation.

The molecular mechanisms of tungstate activity in diabetes have been uncovered. Researchers have identified the pathways through which sodium tungstate improves pancreatic function and beta cell proliferation.

Related Articles


A team led by Professor Ramon Gomis at the Hospital Clinic de Barcelona, Spain, studied the effects of sodium tungstate on pancreatic gene expression in a rat model of diabetes, in order to discover the mechanisms that control the partial pancreatic regeneration induced by this treatment.

He said, "A detailed description of the pathways involved in the pancreatic effects of tungstate is provided in our paper. Essentially, tungstate improves pancreatic function through a combination of hyperglycemia-independent pathways and through its own direct and indirect effects. In addition, the MAPK pathway has a key role in the tungstate-induced increase of beta cell proliferation".

Speaking about the results, Professor Gomis said, "We used sodium tungstate treatment of diabetic animals as a tool to search for genes and pathways implicated in pancreatic regeneration after an injury to the pancreas. This study identified genes with a key role in improving pancreatic plasticity, and these could be used as therapeutic targets for the future treatment of diabetes"


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jordi Altirriba, Albert Barbera, Hector Del Zotto, Belen Nadal, Sandra Piquer, Alex Sanchez-Pla, Juan J Gagliardino and Ramon Gomis. Molecular mechanisms of tungstate-induced pancreatic plasticity: a transcriptomics approach. BMC Genomics, (in press) [link]

Cite This Page:

BioMed Central. "The Anti-diabetic Effects Of Sodium Tungstate Revealed." ScienceDaily. ScienceDaily, 28 August 2009. <www.sciencedaily.com/releases/2009/08/090827192334.htm>.
BioMed Central. (2009, August 28). The Anti-diabetic Effects Of Sodium Tungstate Revealed. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2009/08/090827192334.htm
BioMed Central. "The Anti-diabetic Effects Of Sodium Tungstate Revealed." ScienceDaily. www.sciencedaily.com/releases/2009/08/090827192334.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Christmas Kissing Good for Health

Christmas Kissing Good for Health

Reuters - Innovations Video Online (Dec. 22, 2014) Scientists in Amsterdam say couples transfer tens of millions of microbes when they kiss, encouraging healthy exposure to bacteria. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Brain-Dwelling Tapeworm Reveals Genetic Secrets

Brain-Dwelling Tapeworm Reveals Genetic Secrets

Reuters - Innovations Video Online (Dec. 22, 2014) Cambridge scientists have unravelled the genetic code of a rare tapeworm that lived inside a patient's brain for at least four year. Researchers hope it will present new opportunities to diagnose and treat this invasive parasite. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins