Featured Research

from universities, journals, and other organizations

Less Invasive Procedure For Repair Of Abdominal Aortic Aneurysm May Reduce Short-term Risk Of Death

Date:
October 14, 2009
Source:
JAMA and Archives Journals
Summary:
Patients who received the less-invasive endovascular repair of an abdominal aortic aneurysm had a lower risk of death in the first 30 days after the procedure compared to patients who an open repair, but both procedures had similar rates of death after two years, according to a new study.

Patients who received the less-invasive endovascular repair of an abdominal aortic aneurysm had a lower risk of death in the first 30 days after the procedure compared to patients who an open repair, but both procedures had similar rates of death after two years, according to a study in the October 14 issue of JAMA, a theme issue on surgical care.

Related Articles


Frank A. Lederle, M.D., of the Veterans Affairs Medical Center, Minneapolis, presented the findings of the study at a JAMA media briefing in Chicago.

"Each year in the United States, 45,000 patients with unruptured abdominal aortic aneurysm (AAA) undergo elective repair, resulting in more than 1,400 perioperative [the first 30 days after surgery or inpatient status] deaths," according to background information in the article. Endovascular repair, performed through a catheter inserted into an artery, was developed to provide a less invasive method than the standard open procedure, which involves an abdominal incision. But "limited data are available to assess whether endovascular repair of AAA improves short-term outcomes compared with traditional open repair," the authors write.

Dr. Lederle and colleagues are conducting a multicenter clinical trial to examine outcomes after elective endovascular and open repair of AAA. This is an ongoing 9-year trial, with this interim report including postoperative outcomes of up to 2 years for 881 patients (age 49 years or older). Patients were randomized to either endovascular (n = 444) or open (n = 437) repair of AAA. Average follow-up was 1.8 years.

The researchers found that the rate of death after surgery was significantly higher for open repair at 30 days (0.2 percent vs. 2.3 percent), and at 30 days or during hospitalization (0.5 percent vs. 3.0 percent). But there was no significant difference in all-cause death at two years (7.0 percent vs. 9.8 percent), and death after the perioperative period was similar in the two groups (6.1 percent vs. 6.6 percent).

Patients in the endovascular repair group had reduced procedure time, blood loss and duration of mechanical ventilation. "Hospital and ICU stays were shorter with endovascular repair and need for transfusion was decreased. No significant differences were observed in major morbidities, secondary procedures, or aneurysm-related hospitalizations," the authors write.

"Longer-term data are needed to fully assess the relative merits of the 2 procedures."


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. Frank A. Lederle; Julie A. Freischlag; Tassos C. Kyriakides; Frank T. Padberg, Jr; Jon S. Matsumura; Ted R. Kohler; Peter H. Lin; Jessie M. Jean-Claude; Dolores F. Cikrit; Kathleen M. Swanson; Peter N. Peduzzi; for the Open Versus Endovascular Repair (OVER) Veterans Affairs Cooperative Study Group. Outcomes Following Endovascular vs Open Repair of Abdominal Aortic Aneurysm: A Randomized Trial. JAMA, 2009; 302 (14): 1535-1542 [link]

Cite This Page:

JAMA and Archives Journals. "Less Invasive Procedure For Repair Of Abdominal Aortic Aneurysm May Reduce Short-term Risk Of Death." ScienceDaily. ScienceDaily, 14 October 2009. <www.sciencedaily.com/releases/2009/10/091013112512.htm>.
JAMA and Archives Journals. (2009, October 14). Less Invasive Procedure For Repair Of Abdominal Aortic Aneurysm May Reduce Short-term Risk Of Death. ScienceDaily. Retrieved March 30, 2015 from www.sciencedaily.com/releases/2009/10/091013112512.htm
JAMA and Archives Journals. "Less Invasive Procedure For Repair Of Abdominal Aortic Aneurysm May Reduce Short-term Risk Of Death." ScienceDaily. www.sciencedaily.com/releases/2009/10/091013112512.htm (accessed March 30, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, March 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins