Featured Research

from universities, journals, and other organizations

Migraine Sufferers More Prone To Hangover Headache

Date:
October 19, 2009
Source:
Thomas Jefferson University
Summary:
Migraine sufferers, beware. You may be more prone to an alcohol-induced headache after a night of drinking, according to researchers.

Migraine sufferers, beware. You may be more prone to an alcohol-induced headache after a night of drinking, according to researchers from the Jefferson Headache Center. The research will be presented at Neuroscience 2009, the Annual Meeting of the Society for Neuroscience, in Chicago.

Related Articles


Until now, studying the mechanism behind migraine and other forms of recurrent headaches has not been possible in an animal model, according to Michael Oshinsky, Ph.D., assistant professor of Neurology at Jefferson Medical College of Thomas Jefferson University, and a member of the Jefferson Headache Center team. In order to facilitate the study of migraine, Dr. Oshinsky developed a rat model in which headaches are induced by repeatedly stimulating, over weeks to months, the brain's dura mater with an inflammatory mixture.

Dr. Oshinsky and Christina Maxwell, a Ph.D. student in the Neuroscience program at the Jefferson College of Graduate Studies, used their rat model to study the effects of alcohol on rats who suffer recurrent migraines, compared to rats that do not get headaches. They analyzed four groups of rats: two groups received repeated dural simulation, followed by an oral ingestion of saline or alcohol (the equivalent of one to two shots of liquor). Two control groups received no inflammatory stimulation, and received the similar oral ingestion of saline or alcohol.

Migraine headaches are associated with hypersensitivity to light, sound and light touch on the head and face. The researchers measured the rats' sensitivity to touch around the eye, using von Frey monofilaments. They monitored the change in pain threshold of the face resulting from the repeated dural stimulation.

The rats that received dural stimulation followed by alcohol showed an initial analgesic effect within the first two hours after alcohol ingestion. However, four to six hours later, their pain sensitivity increased, indicating a more painful state. There were no changes in alcohol-induced sensitivity in the control groups.

"Our results suggest that dehydration or impurities in alcohol are not responsible for hangover headache," Dr. Oshinsky said. "Since these rats were sufficiently hydrated and the alcohol they received contained no impurities, the alcohol itself or a metabolite must be causing the hangover-like headache. These data confirm the clinical observation that people with migraine are more susceptible to alcohol-induced headaches."

Dr. Oshinsky and his laboratory are now also studying the mechanism for the induction of headache, and also the metabolites of alcohol that cause hangover.


Story Source:

The above story is based on materials provided by Thomas Jefferson University. Note: Materials may be edited for content and length.


Cite This Page:

Thomas Jefferson University. "Migraine Sufferers More Prone To Hangover Headache." ScienceDaily. ScienceDaily, 19 October 2009. <www.sciencedaily.com/releases/2009/10/091018171808.htm>.
Thomas Jefferson University. (2009, October 19). Migraine Sufferers More Prone To Hangover Headache. ScienceDaily. Retrieved March 28, 2015 from www.sciencedaily.com/releases/2009/10/091018171808.htm
Thomas Jefferson University. "Migraine Sufferers More Prone To Hangover Headache." ScienceDaily. www.sciencedaily.com/releases/2009/10/091018171808.htm (accessed March 28, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Saturday, March 28, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

AAA: Distracted Driving a Serious Teen Problem

AAA: Distracted Driving a Serious Teen Problem

AP (Mar. 25, 2015) While distracted driving is not a new problem for teens, new research from the AAA Foundation for Traffic Safety says it&apos;s much more serious than previously thought. (March 25) Video provided by AP
Powered by NewsLook.com
Smartphone Use Changing Our Brain and Thumb Interaction, Say Researchers

Smartphone Use Changing Our Brain and Thumb Interaction, Say Researchers

Reuters - Innovations Video Online (Mar. 25, 2015) European researchers say our smartphone use offers scientists an ideal testing ground for human brain plasticity. Dr Ako Ghosh&apos;s team discovered that the brains and thumbs of smartphone users interact differently from those who use old-fashioned handsets. Jim Drury went to meet him. Video provided by Reuters
Powered by NewsLook.com
Many Don't Know They Have Alzheimer's, But Their Doctors Do

Many Don't Know They Have Alzheimer's, But Their Doctors Do

Newsy (Mar. 24, 2015) According to a new study by the Alzheimer&apos;s Association, more than half of those who have the degenerative brain disease aren&apos;t told by their doctors. Video provided by Newsy
Powered by NewsLook.com
A Quick 45-Minute Nap Can Improve Your Memory

A Quick 45-Minute Nap Can Improve Your Memory

Newsy (Mar. 23, 2015) Researchers found those who napped for 45 minutes to an hour before being tested on information recalled it five times better than those who didn&apos;t. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins