Featured Research

from universities, journals, and other organizations

Optimized Inhaler Mouthpiece Design Allows For More Effective Drug Delivery

Date:
October 24, 2009
Source:
American Association of Pharmaceutical Scientists
Summary:
Redesign of mouthpieces for aerosol inhaler devices allows for drugs to be more effectively delivered to the lungs and may allow for a new class of aerosol administered medications.

Researchers have developed an optimized mouthpiece design to aid efficient drug delivery to the lungs by reducing the amount of medication wasted as it passes through the mouthpiece of an aerosol inhaler. With current inhaler designs, only approximately 10 to 20 percent of asthma medications are delivered to the lungs. And, because the lungs provide a direct and effective route of entry for medications into the bloodstream, an optimized mouthpiece design will reduce medication waste and may provide reproducible delivery of future inhaled medications.

"Through a process of computational and experimental analysis and design for a new inhaler, we were able to optimize a prototype mouthpiece that allowed for more medication to pass through the mouthpiece and be available to reach the lungs," said Michael Hindle, Ph.D., research associate professor at Virginia Commonwealth University (VCU) School of Pharmacy and presenter at the 2009 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition. "By optimizing the design, it will help ensure delivery efficiency so less medication will be wasted and more will be effectively delivered to the lungs for relief from symptoms."

Dr. Hindle adds that this rational computational inhaler analysis and design approach, which was developed with Worth Longest, Ph.D. from the School of Engineering at VCU, may be applicable for other inhalers and medications that require reproducible delivery. "Insulin is an example of a drug that requires a reproducible delivery strategy that can be administered painlessly and as effectively through aerosol inhalers."

Further research at this year's AAPS Annual Meeting and Exposition will address computational and experimental design methods to improve inhaler performance and how they affect the future of aerosol drug delivery.


Story Source:

The above story is based on materials provided by American Association of Pharmaceutical Scientists. Note: Materials may be edited for content and length.


Cite This Page:

American Association of Pharmaceutical Scientists. "Optimized Inhaler Mouthpiece Design Allows For More Effective Drug Delivery." ScienceDaily. ScienceDaily, 24 October 2009. <www.sciencedaily.com/releases/2009/10/091021172657.htm>.
American Association of Pharmaceutical Scientists. (2009, October 24). Optimized Inhaler Mouthpiece Design Allows For More Effective Drug Delivery. ScienceDaily. Retrieved August 20, 2014 from www.sciencedaily.com/releases/2009/10/091021172657.htm
American Association of Pharmaceutical Scientists. "Optimized Inhaler Mouthpiece Design Allows For More Effective Drug Delivery." ScienceDaily. www.sciencedaily.com/releases/2009/10/091021172657.htm (accessed August 20, 2014).

Share This




More Health & Medicine News

Wednesday, August 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Possible Ebola Patient in Isolation at California Hospital

Possible Ebola Patient in Isolation at California Hospital

Reuters - US Online Video (Aug. 20, 2014) — A patient who may have been exposed to the Ebola virus is in isolation at the Kaiser Permanente South Sacramento Medical Center. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Raw: World's Oldest Man Lives in Japan

Raw: World's Oldest Man Lives in Japan

AP (Aug. 20, 2014) — A 111-year-old Japanese was certified as the world's oldest man by Guinness World Records on Wednesday. Sakari Momoi, a native of Fukushima in northern Japan, was given a certificate at a hospital in Tokyo. (Aug. 20) Video provided by AP
Powered by NewsLook.com
Do More Wedding Guests Make A Happier Marriage?

Do More Wedding Guests Make A Happier Marriage?

Newsy (Aug. 20, 2014) — A new study found couples who had at least 150 guests at their weddings were more likely to report being happy in their marriages. Video provided by Newsy
Powered by NewsLook.com
Ebola-Hit Sierra Leone's Freetown a City on Edge

Ebola-Hit Sierra Leone's Freetown a City on Edge

AFP (Aug. 19, 2014) — Residents of Sierra Leone's capital voice their fears as the Ebola virus sweeps through west Africa. Duration: 00:56 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins