Featured Research

from universities, journals, and other organizations

Optimized Inhaler Mouthpiece Design Allows For More Effective Drug Delivery

Date:
October 24, 2009
Source:
American Association of Pharmaceutical Scientists
Summary:
Redesign of mouthpieces for aerosol inhaler devices allows for drugs to be more effectively delivered to the lungs and may allow for a new class of aerosol administered medications.

Researchers have developed an optimized mouthpiece design to aid efficient drug delivery to the lungs by reducing the amount of medication wasted as it passes through the mouthpiece of an aerosol inhaler. With current inhaler designs, only approximately 10 to 20 percent of asthma medications are delivered to the lungs. And, because the lungs provide a direct and effective route of entry for medications into the bloodstream, an optimized mouthpiece design will reduce medication waste and may provide reproducible delivery of future inhaled medications.

"Through a process of computational and experimental analysis and design for a new inhaler, we were able to optimize a prototype mouthpiece that allowed for more medication to pass through the mouthpiece and be available to reach the lungs," said Michael Hindle, Ph.D., research associate professor at Virginia Commonwealth University (VCU) School of Pharmacy and presenter at the 2009 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition. "By optimizing the design, it will help ensure delivery efficiency so less medication will be wasted and more will be effectively delivered to the lungs for relief from symptoms."

Dr. Hindle adds that this rational computational inhaler analysis and design approach, which was developed with Worth Longest, Ph.D. from the School of Engineering at VCU, may be applicable for other inhalers and medications that require reproducible delivery. "Insulin is an example of a drug that requires a reproducible delivery strategy that can be administered painlessly and as effectively through aerosol inhalers."

Further research at this year's AAPS Annual Meeting and Exposition will address computational and experimental design methods to improve inhaler performance and how they affect the future of aerosol drug delivery.


Story Source:

The above story is based on materials provided by American Association of Pharmaceutical Scientists. Note: Materials may be edited for content and length.


Cite This Page:

American Association of Pharmaceutical Scientists. "Optimized Inhaler Mouthpiece Design Allows For More Effective Drug Delivery." ScienceDaily. ScienceDaily, 24 October 2009. <www.sciencedaily.com/releases/2009/10/091021172657.htm>.
American Association of Pharmaceutical Scientists. (2009, October 24). Optimized Inhaler Mouthpiece Design Allows For More Effective Drug Delivery. ScienceDaily. Retrieved September 14, 2014 from www.sciencedaily.com/releases/2009/10/091021172657.htm
American Association of Pharmaceutical Scientists. "Optimized Inhaler Mouthpiece Design Allows For More Effective Drug Delivery." ScienceDaily. www.sciencedaily.com/releases/2009/10/091021172657.htm (accessed September 14, 2014).

Share This



More Health & Medicine News

Sunday, September 14, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Respiratory Virus Spreads To Northeast, Now In 21 States

Respiratory Virus Spreads To Northeast, Now In 21 States

Newsy (Sep. 14, 2014) The respiratory virus Enterovirus D68, which targets children, has spread from the Midwest to 21 states. Video provided by Newsy
Powered by NewsLook.com
Shocker: Journalists Are Utterly Addicted To Coffee

Shocker: Journalists Are Utterly Addicted To Coffee

Newsy (Sep. 13, 2014) A U.K. survey found that journalists consumed the most amount of coffee, but that's only the tip of the coffee-related statistics iceberg. Video provided by Newsy
Powered by NewsLook.com
Contagious Respiratory Illness Continues to Spread Across U.S.

Contagious Respiratory Illness Continues to Spread Across U.S.

Reuters - US Online Video (Sep. 12, 2014) Hundreds of children in several states have been stricken by a serious respiratory illness that is spreading across the U.S. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Batters Sierra Leone Economy Too

Ebola Batters Sierra Leone Economy Too

Reuters - Business Video Online (Sep. 12, 2014) The World Health Organisation warns that local health workers in West Africa can't keep up with Ebola - and among those countries hardest hit by the outbreak, the economic damage is coming into focus, too. As David Pollard reports, Sierra Leone admits that growth in one of the poorest economies in the region is taking a beating. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

    Technology News



    Save/Print:
    Share:

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile: iPhone Android Web
    Follow: Facebook Twitter Google+
    Subscribe: RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins