Featured Research

from universities, journals, and other organizations

New Combination Therapy Looks Promising Against Ulcer Bacteria

Date:
January 6, 2010
Source:
American College of Gastroenterology
Summary:
Results of a new study reveal that a seven-day course of LOAD therapy is superior to LAC at eliminating the H. pylori bacterium in patients with gastritis and peptic ulcers.

Helicobater pylori, a bacteria implicated in peptic ulcers and gastritis, was eradicated in 95 percent patients who took a 7-day course of combination therapy with levofloxacin, omeprazole, nitazoxanide (Alinia®) and doxycycline (LOAD) compared to eradication in only 80.9 percent of patients on lansoprazole, amoxicillin and clarithromycin (LAC) for seven days.

Results of a new study presented at the Annual Scientific Meeting of the American College of Gastroenterology reveal LOAD therapy is superior to LAC at eliminating the bacterium in patients with gastritis and peptic ulcers. Moreover, Dr. Patrick Basu and his colleagues at Columbia University College of Physicians and Surgeons found that a shorter course of the four-drug combination, seven days vs. a ten-day treatment, is equally effective.

The study included 135 patients with treatment naïve Helicobacter pylori infection who were randomized to LOAD (7 or 10 days) vs. LAC (10 days). There was a total wash out period of six weeks from any prior antibiotic and PPI use prior to the initiation of therapy.

"H. pylori gastritis is a global threat for gastric carcinoma and many therapies have been explored to eradicate this infection with variable success rates," explained Dr. Basu. "Our study demonstrates the therapeutic superiority of LOAD therapy over LAC therapy in a treatment naïve population of patients with H. pylori."


Story Source:

The above story is based on materials provided by American College of Gastroenterology. Note: Materials may be edited for content and length.


Cite This Page:

American College of Gastroenterology. "New Combination Therapy Looks Promising Against Ulcer Bacteria." ScienceDaily. ScienceDaily, 6 January 2010. <www.sciencedaily.com/releases/2009/10/091026125138.htm>.
American College of Gastroenterology. (2010, January 6). New Combination Therapy Looks Promising Against Ulcer Bacteria. ScienceDaily. Retrieved August 20, 2014 from www.sciencedaily.com/releases/2009/10/091026125138.htm
American College of Gastroenterology. "New Combination Therapy Looks Promising Against Ulcer Bacteria." ScienceDaily. www.sciencedaily.com/releases/2009/10/091026125138.htm (accessed August 20, 2014).

Share This




More Health & Medicine News

Wednesday, August 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Possible Ebola Patient in Isolation at California Hospital

Possible Ebola Patient in Isolation at California Hospital

Reuters - US Online Video (Aug. 20, 2014) — A patient who may have been exposed to the Ebola virus is in isolation at the Kaiser Permanente South Sacramento Medical Center. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Raw: World's Oldest Man Lives in Japan

Raw: World's Oldest Man Lives in Japan

AP (Aug. 20, 2014) — A 111-year-old Japanese was certified as the world's oldest man by Guinness World Records on Wednesday. Sakari Momoi, a native of Fukushima in northern Japan, was given a certificate at a hospital in Tokyo. (Aug. 20) Video provided by AP
Powered by NewsLook.com
Do More Wedding Guests Make A Happier Marriage?

Do More Wedding Guests Make A Happier Marriage?

Newsy (Aug. 20, 2014) — A new study found couples who had at least 150 guests at their weddings were more likely to report being happy in their marriages. Video provided by Newsy
Powered by NewsLook.com
Ebola-Hit Sierra Leone's Freetown a City on Edge

Ebola-Hit Sierra Leone's Freetown a City on Edge

AFP (Aug. 19, 2014) — Residents of Sierra Leone's capital voice their fears as the Ebola virus sweeps through west Africa. Duration: 00:56 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins