Featured Research

from universities, journals, and other organizations

Can Charcoal Fight Heart Disease In Kidney Patients?

Date:
November 1, 2009
Source:
American Society of Nephrology
Summary:
Charcoal may provide a new approach to managing the high rate of heart disease in patients with advanced kidney disease, according to preliminary research.

Charcoal may provide a new approach to managing the high rate of heart disease in patients with advanced kidney disease, according to preliminary research being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA.

Related Articles


Patients with advanced kidney disease have high rates of atherosclerosis ("hardening of the arteries") and death from heart disease. Oral activated charcoal -- a product called AST-120 -- has traditionally been used as an emergency treatment for certain types of poisoning. Recent studies have suggested that AST-120 may exert beneficial effects in kidney disease.

"We found that oral activated charcoal lessens atherosclerotic lesions in experimental mice with kidney damage," comments Valentina Kon, MD (Vanderbilt University). "This is especially important because there is no effective treatment to reduce the high rate of cardiovascular mortality in patients with end-stage renal disease."

The researchers studied the effects of AST-120 in mice genetically engineered to develop atherosclerosis. The effects were assessed in mice with different levels of kidney mass.

In mice with profoundly reduced renal mass, treatment with AST-120 led to a dramatic decrease in atherosclerosis. This was so even when charcoal treatment was delayed. The improvement in atherosclerosis was unrelated to changes in blood pressure or cholesterol levels. Rather, the effect appeared related to reduced inflammation in the blood vessels.

In mice, oral activated charcoal appears to reduce atherosclerosis associated with kidney disease. The effect is present at different levels of kidney function, in very advanced atherosclerosis, and even when treatment is delayed. More research is needed to see if AST-120 offers similar benefits in humans with kidney disease.

The research was supported by Kureha Chemical Industry Co., Ltd., Tokyo, which makes AST-120.


Story Source:

The above story is based on materials provided by American Society of Nephrology. Note: Materials may be edited for content and length.


Cite This Page:

American Society of Nephrology. "Can Charcoal Fight Heart Disease In Kidney Patients?." ScienceDaily. ScienceDaily, 1 November 2009. <www.sciencedaily.com/releases/2009/11/091101132547.htm>.
American Society of Nephrology. (2009, November 1). Can Charcoal Fight Heart Disease In Kidney Patients?. ScienceDaily. Retrieved January 29, 2015 from www.sciencedaily.com/releases/2009/11/091101132547.htm
American Society of Nephrology. "Can Charcoal Fight Heart Disease In Kidney Patients?." ScienceDaily. www.sciencedaily.com/releases/2009/11/091101132547.htm (accessed January 29, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, January 29, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Malnutrition on the Rise as Violence Flares in C. Africa

Malnutrition on the Rise as Violence Flares in C. Africa

AFP (Jan. 28, 2015) Violence can flare up at any moment in Bambari with only a bridge separating Muslims and Christians. Malnutrition is on the rise and lack of water means simple cooking fires threaten to destroy makeshift camps where people are living. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com
Poultry Culled in Taiwan to Thwart Bird Flu

Poultry Culled in Taiwan to Thwart Bird Flu

Reuters - News Video Online (Jan. 28, 2015) Taiwan culls over a million poultry in efforts to halt various strains of avian flu. Julie Noce reports. Video provided by Reuters
Powered by NewsLook.com
Media Criticizing Parents For Not Vaccinating Children

Media Criticizing Parents For Not Vaccinating Children

Newsy (Jan. 28, 2015) As the Disneyland measles outbreak continues to spread, the media says parents who choose not to vaccinate their children are part of the cause. Video provided by Newsy
Powered by NewsLook.com
Shark Bite Victim Making Amazing Recovery

Shark Bite Victim Making Amazing Recovery

AP (Jan. 27, 2015) A Texas woman who lost more than five pounds of flesh to a shark in the Bahamas earlier this month could be released from a Florida hospital soon. Experts believe she was bitten by a bull shark while snorkeling. (Jan. 27) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins