Featured Research

from universities, journals, and other organizations

Adding Proton Therapy 'Boost' To X-ray Radiation Therapy Reduces Prostate Cancer Recurrences

Date:
November 2, 2009
Source:
American Society for Radiation Oncology
Summary:
Men who receive a "boost" of proton therapy after receiving a standard course of X-ray radiation therapy have fewer prostate cancer recurrences compared to men who did not receive the extra dose of proton radiation.

Men who receive a "boost" of proton therapy after receiving a standard course of X-ray radiation therapy have fewer recurrences of their prostate cancer compared to men who did not receive the extra dose of proton radiation, according to a first-of-its-kind study presented November 2, 2009, at the American Society for Radiation Oncology's 51st Annual Meeting in Chicago. The multi-institutional, randomized trial also shows that the high dose treatment is safe for these patients and causes no severe problems later with urinary or bowel functions.

"There is a lot of interest in proton therapy for prostate cancer. This study proves the importance of giving high radiation doses to prostate cancer patients with low- and intermediate- risk disease because it demonstrates that even these 'favorable' patients still benefit from the extra high-dose treatment," Carl J. Rossi Jr., M.D., a study author and a radiation oncologist at the Loma Linda University Medical Center in Loma Linda, Calif., said. "It also shows that so long as these higher doses are given with a highly conformal technique, such as proton beam therapy, then they can be delivered safely and with minimal side effects.

Proton beam therapy is a form of external beam radiation treatment that uses protons rather than photon X-rays to treat certain types of cancer and other diseases. The physical characteristics of the proton therapy beam allow the radiation oncologist to more effectively reduce the radiation dose to nearby healthy tissue.

During external beam radiation therapy, a beam of radiation is directed through the skin to the cancer and the immediate surrounding area in order to destroy the main tumor and any nearby cancer cells.

The study involved 391 patients with early prostate cancer (cancer that has not spread out of the prostate) receiving proton treatments at Loma Linda University Medical Center and Massachusetts General Hospital in Boston. Patients were randomized to receive either "standard dose" or "high dose" radiation, with proton beams being used to deliver the high-dose radiotherapy to prostate.

Findings show that in patients with a low risk of having the cancer return (recurrence), only six percent of patients who were treated with high dose radiation had the cancer return after 10 years, compared to 29 percent who had conventional radiation doses. Similarly, of the patients with an intermediate risk of cancer recurrence, 37 percent who underwent high dose radiation had cancer come back, versus 45 percent of those who had conventional doses of radiation. There were no significant differences between the two groups in how long they survived and in their urinary and bowel functions.


Story Source:

The above story is based on materials provided by American Society for Radiation Oncology. Note: Materials may be edited for content and length.


Cite This Page:

American Society for Radiation Oncology. "Adding Proton Therapy 'Boost' To X-ray Radiation Therapy Reduces Prostate Cancer Recurrences." ScienceDaily. ScienceDaily, 2 November 2009. <www.sciencedaily.com/releases/2009/11/091102121502.htm>.
American Society for Radiation Oncology. (2009, November 2). Adding Proton Therapy 'Boost' To X-ray Radiation Therapy Reduces Prostate Cancer Recurrences. ScienceDaily. Retrieved August 2, 2014 from www.sciencedaily.com/releases/2009/11/091102121502.htm
American Society for Radiation Oncology. "Adding Proton Therapy 'Boost' To X-ray Radiation Therapy Reduces Prostate Cancer Recurrences." ScienceDaily. www.sciencedaily.com/releases/2009/11/091102121502.htm (accessed August 2, 2014).

Share This




More Health & Medicine News

Saturday, August 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Quintuplets Head Home

Texas Quintuplets Head Home

Reuters - US Online Video (Aug. 1, 2014) After four months in the hospital, the first quintuplets to be born at Baylor University Medical Center head home. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Patient Coming to U.S. for Treatment

Ebola Patient Coming to U.S. for Treatment

Reuters - US Online Video (Aug. 1, 2014) A U.S. aid worker infected with Ebola while working in West Africa will be treated in a high security ward at Emory University in Atlanta. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Vaccine Might Be Coming, But Where's It Been?

Ebola Vaccine Might Be Coming, But Where's It Been?

Newsy (Aug. 1, 2014) Health officials are working to fast-track a vaccine — the West-African Ebola outbreak has killed more than 700. But why didn't we already have one? Video provided by Newsy
Powered by NewsLook.com
Study Links Certain Birth Control Pills To Breast Cancer

Study Links Certain Birth Control Pills To Breast Cancer

Newsy (Aug. 1, 2014) Previous studies have made the link between birth control and breast cancer, but the latest makes the link to high-estrogen oral contraceptives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins