Featured Research

from universities, journals, and other organizations

Colon Cancer Screening More Effective Earlier In Day, Study Finds

Date:
November 10, 2009
Source:
University of California - Los Angeles
Summary:
The effectiveness of a screening colonoscopy may depend on the time of day it is performed. According to a new study, early-morning colonoscopies yielded more polyps per patient than later screenings, and fewer polyps were found hour by hour as the day progressed. The findings point to the need for more research in this area to possibly improve outcomes for colonoscopy procedures.

The effectiveness of a screening colonoscopy may depend on the time of day it is performed. According to a new UCLA study, early-morning colonoscopies yielded more polyps per patient than later screenings, and fewer polyps were found hour by hour as the day progressed.

Related Articles


The findings, published in the November issue of the journal Clinical Gastroenterology and Hepatology, point to the need for more research in this area to possibly improve outcomes for colonoscopy procedures. While the current study was done at a single institution, the clinical setup is much the same in other practice settings, the researchers said.

"Our research was conducted at an academic-affiliated facility that far exceeds published quality benchmarks for colonoscopy outcomes," said study author Dr. Brennan M.R. Spiegel, director of the UCLA/Veterans Affairs Center for Outcomes Research and Education. "So, if this is occurring at such a high-performing academic center, it is probably happening at other facilities across the country."

Spiegel noted that although this is a new area of research, other studies have reached similar conclusions, including recent research from the Cleveland Clinic published in the July issue of the American Journal of Gastroenterology.

A colonoscopy is the only test that allows the identification and removal of polyps from the entire colon. Studies have shown that polyp removal has been associated with a 60- to 90-percent reduction in colorectal cancer, which is the second leading cause of death in the United States.

"Successful colonoscopy procedures depend on a number of key patient, provider and procedural factors -- and time of day may also be important as well," said Spiegel, who is an assistant professor of digestive diseases at the David Geffen School of Medicine at UCLA and the VA Greater Los Angeles Healthcare System.

During the study, researchers tracked 477 patients receiving colonoscopies over the course of one year at a single VA hospital. Researchers found that early-morning cases, started at 8:30 a.m. or earlier, yielded 27 percent more polyps -- 0.19 more overall polyps and 0.17 more premalignant polyps -- per patient than later cases. The amount of polyps discovered decreased hour by hour as the day progressed. This translates into less than a quarter of a polyp per patient, so the risk for individual patients is very low.

"Although individual patient risk is very low, multiplying this effect by thousands of patients across the United States could mean we're missing lots of polyps, some of which might turn into cancer one day," Spiegel said. "More research needs to be done at a wide range of centers to pinpoint why there's a decrease in the number of polyps found later in the day and to identify ways we might improve outcomes."

Spiegel added that colonoscopy remains a highly effective means of screening for colon cancer whatever the time of day and warned against patients insisting on being the first case of the day.

"The impact of appointment time for any individual patient is very, very small," he said. "Patients should feel confident that colonoscopy is helpful regardless of time of day and should be more focused on the quality and experience of their doctor rather than the time of their appointment."

The study authors noted that these findings were independent, after accounting for a number of demographic and clinical factors, including age, gender and history of polyps or cancer, as well as the skill level of the physician.

Researchers added that colonoscopies performed in the morning may have better results partly due to improved bowel preparation the night before, but that this didn't completely explain the overall study results.

Spiegel said that fatigue may play a role, as it does in other professions with prolonged and repetitive activities, like trucking, surgery and aviation.

"We may find that setting a cap on the duration of endoscopic work shifts or other types of adjustments may be helpful," he said.

The study was funded by a Veterans Affairs Health Services Research and Development grant and a Career Development Transition Award.

Other study others included Michael Y. Chan, of the division of digestive diseases at the David Geffen School of Medicine at UCLA, and Hartley Cohen, of the department of gastroenterology at the VA Greater Los Angeles Healthcare System.


Story Source:

The above story is based on materials provided by University of California - Los Angeles. The original article was written by Rachel Champeau. Note: Materials may be edited for content and length.


Cite This Page:

University of California - Los Angeles. "Colon Cancer Screening More Effective Earlier In Day, Study Finds." ScienceDaily. ScienceDaily, 10 November 2009. <www.sciencedaily.com/releases/2009/11/091103121614.htm>.
University of California - Los Angeles. (2009, November 10). Colon Cancer Screening More Effective Earlier In Day, Study Finds. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2009/11/091103121614.htm
University of California - Los Angeles. "Colon Cancer Screening More Effective Earlier In Day, Study Finds." ScienceDaily. www.sciencedaily.com/releases/2009/11/091103121614.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins