Featured Research

from universities, journals, and other organizations

Breast Density Associated With Increased Risk Of Cancer Recurrence

Date:
November 9, 2009
Source:
American Cancer Society
Summary:
A new study finds that women treated for breast cancer are at higher risk of cancer recurrence if they have dense breasts. The study's results indicate that breast cancer patients with dense breasts may benefit from additional therapies following surgery, such as radiation.

A new study finds that women treated for breast cancer are at higher risk of cancer recurrence if they have dense breasts. Published in the December 15, 2009 issue of Cancer, a peer-reviewed journal of the American Cancer Society, the study's results indicate that breast cancer patients with dense breasts may benefit from additional therapies following surgery, such as radiation.

Previous studies indicate that women with dense breast tissue are at increased risk of breast cancer. Researchers have suspected that high breast density may also increase the risk of cancer recurrence after lumpectomy, but this theory has not been thoroughly studied.

Researchers led by Steven A. Narod, MD, of the Women's College Research Institute in Toronto, reviewed the medical records of 335 patients who had undergone lumpectomy for breast cancer. Investigators monitored the patients for cancer recurrence and compared recurrence with breast density as seen on mammogram, categorized as low density (<25 percent dense tissue), intermediate density (25 percent to 50 percent dense tissue) or high density (>50 percent dense tissue).

The researchers found that patients with the highest breast density had a much greater risk of cancer recurrence than did women with the lowest breast density. Over ten years, women in the highest breast density category had a 21 percent chance of cancer recurrence, compared with a 5 percent chance among women in the lowest category. The difference in the recurrence rates at ten years was even more pronounced for women who did not receive radiation. In those women, 40 percent with high-density breast tissue had a recurrence compared with none of the patients with low density.

"The composition of the breast tissue surrounding the breast cancer is important in predicting whether or not a breast cancer will return after surgery," concluded Dr. Narod. The authors say their findings indicate that women with low breast density, who have a low chance of recurrence after surgery, may not need radiation but that women with high breast density could significantly benefit from the additional therapy.


Story Source:

The above story is based on materials provided by American Cancer Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Tulin Cil, Eve Fishell, Wedad Hanna, Ping Sun, Ellen Rawlinson, Steven A. Narod, and David R. McCready. Mammographic density and the risk of breast cancer recurrence following breast-conserving surgery. Cancer, Published Online: November 9, 2009 DOI: 10.1002/cncr.24638

Cite This Page:

American Cancer Society. "Breast Density Associated With Increased Risk Of Cancer Recurrence." ScienceDaily. ScienceDaily, 9 November 2009. <www.sciencedaily.com/releases/2009/11/091109090427.htm>.
American Cancer Society. (2009, November 9). Breast Density Associated With Increased Risk Of Cancer Recurrence. ScienceDaily. Retrieved April 23, 2014 from www.sciencedaily.com/releases/2009/11/091109090427.htm
American Cancer Society. "Breast Density Associated With Increased Risk Of Cancer Recurrence." ScienceDaily. www.sciencedaily.com/releases/2009/11/091109090427.htm (accessed April 23, 2014).

Share This



More Health & Medicine News

Wednesday, April 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Big Pharma Braces for M&A Wave

Big Pharma Braces for M&A Wave

Reuters - Business Video Online (Apr. 22, 2014) Big pharma on the move as Novartis boss, Joe Jimenez, tells Reuters about plans to transform his company via an asset exchange with GSK, and Astra Zeneca shares surge on speculation that Pfizer is looking for a takeover. Joanna Partridge reports. Video provided by Reuters
Powered by NewsLook.com
Study Says Most Crime Not Linked To Mental Illness

Study Says Most Crime Not Linked To Mental Illness

Newsy (Apr. 22, 2014) A new study finds most crimes committed by people with mental illness are not caused by symptoms of their illness or disorder. Video provided by Newsy
Powered by NewsLook.com
Hagel Gets Preview of New High-Tech Projects

Hagel Gets Preview of New High-Tech Projects

AP (Apr. 22, 2014) Defense Secretary Chuck Hagel is given hands-on demonstrations Tuesday of some of the newest research from DARPA _ the military's Defense Advanced Research Projects Agency program. (April 22) Video provided by AP
Powered by NewsLook.com
How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins