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Solving the 50-year-old puzzle of thalidomide

Date:
November 20, 2009
Source:
Wiley-Blackwell
Summary:
Resurgence of thalidomide use in Africa and South America raises the urgent need to isolate the negative side effects by identifying the drug's "common mechanism."

Research into the controversial drug thalidomide reveals that the mechanism through which the drug causes limb defects is the same process which causes it to damage internal organs and other tissues. The article, published in Bio-Essays, outlines the challenges surrounding thalidomide research and claims that confirmation of a 'common mechanism' could lead to new treatments for Leprosy, Crohn's Disease, AIDS and some forms of cancer.


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Journal Reference:

  1. Vargesson et al. Thalidomide-induced limb defects: resolving a 50-year-old puzzle. BioEssays, 2009; 31 (12): 1327 DOI: 10.1002/bies.200900103

Cite This Page:

Wiley-Blackwell. "Solving the 50-year-old puzzle of thalidomide." ScienceDaily. ScienceDaily, 20 November 2009. <www.sciencedaily.com/releases/2009/11/091117094839.htm>.
Wiley-Blackwell. (2009, November 20). Solving the 50-year-old puzzle of thalidomide. ScienceDaily. Retrieved April 23, 2014 from www.sciencedaily.com/releases/2009/11/091117094839.htm
Wiley-Blackwell. "Solving the 50-year-old puzzle of thalidomide." ScienceDaily. www.sciencedaily.com/releases/2009/11/091117094839.htm (accessed April 23, 2014).

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