Featured Research

from universities, journals, and other organizations

Study links real-time data to flu vaccine strategies

Date:
December 29, 2009
Source:
Arizona State University
Summary:
Adaptive vaccination strategies, based on age patterns of hospitalizations and deaths monitored in real-time during the early stages of a pandemic, outperform seasonal influenza vaccination allocation strategies, according to a new article.

Adaptive vaccination strategies, based on age patterns of hospitalizations and deaths monitored in real-time during the early stages of a pandemic, outperform seasonal influenza vaccination allocation strategies, according to findings reported Dec. 3 by researchers, including two from Arizona State University, in the online journal PLoS ONE.

Using data from the A(H1N1) influenza outbreak in Mexico earlier this year, the authors conclude that a modeling approach that targets specific age groups for vaccinations, could help countries develop policies to mitigate the impact of ongoing and secondary pandemic waves.

"These new data shed light on which age groups are at high risk of infection and transmission during a pandemic influenza outbreak. Unlike seasonal vaccination strategies that target young children and seniors, our adaptive strategy based on early epidemiological data prioritized the young and adults between the ages of 20 and 59 years, which was based on the pattern of hospitalizations and deaths during the Mexican pandemic outbreak," says mathematical epidemiologist Gerardo Chowell-Puente, an assistant professor in the School of Human Evolution and Social Change in ASU's College of Liberal Arts and Sciences.

The adaptive vaccination strategy relied on data reported to the Mexican National Epidemiological Surveillance System on hospitalization and deaths 25 and 37 days into the outbreak. The study's adaptive strategy yielded a 37 percent reduction in hospitalizations and 42 percent reduction in deaths if the vaccinations started on day 25 of the outbreak and reached 20 percent of the population. The benefits of the strategy were slightly lower on day 37 of the outbreak, providing a 35 percent reduction in influenza-related deaths and 22 percent reduction in hospitalizations when compared to seasonal influenza that targets traditional high-risk age groups (infants, young children and persons 65 years and older).

"The adaptive strategy was found to be effective in reducing the number of hospitalizations and deaths during a pandemic influenza when vaccine resources are scarce," says Chowell-Puente. "Knowledge of age-specific rates is crucial in helping policymakers develop intervention policies that could help to save lives. If vaccine supplies are limited, targeting these age groups should be considered."

Chowell-Puente is co-author of the study "Adaptive vaccination strategies to mitigate pandemic influenza: Mexico as a case study," which appears in PLoS One, the online journal published by the Public Library of Science. Other authors include Xiaohong Wang with ASU's Mathematical and Computational Modeling Sciences Center; Cιcile Viboud and Mark A. Miller with the Fogarty International Center, National Institutes of Health; and Stefano Bertozzi with Mexico's National Institute of Public Health and the University of California, Berkeley.

Chowell-Puente also is co-author of a study of the A(H1N1) influenza pandemic strain, which reported an age shift in the proportion of cases toward a younger population when compared with historical patterns of seasonal influenza in Mexico. Those findings were published June 29 online in the New England Journal of Medicine.


Story Source:

The above story is based on materials provided by Arizona State University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Chowell et al. Adaptive Vaccination Strategies to Mitigate Pandemic Influenza: Mexico as a Case Study. PLoS ONE, 2009; 4 (12): e8164 DOI: 10.1371/journal.pone.0008164

Cite This Page:

Arizona State University. "Study links real-time data to flu vaccine strategies." ScienceDaily. ScienceDaily, 29 December 2009. <www.sciencedaily.com/releases/2009/12/091203163144.htm>.
Arizona State University. (2009, December 29). Study links real-time data to flu vaccine strategies. ScienceDaily. Retrieved April 23, 2014 from www.sciencedaily.com/releases/2009/12/091203163144.htm
Arizona State University. "Study links real-time data to flu vaccine strategies." ScienceDaily. www.sciencedaily.com/releases/2009/12/091203163144.htm (accessed April 23, 2014).

Share This



More Health & Medicine News

Wednesday, April 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Big Pharma Braces for M&A Wave

Big Pharma Braces for M&A Wave

Reuters - Business Video Online (Apr. 22, 2014) — Big pharma on the move as Novartis boss, Joe Jimenez, tells Reuters about plans to transform his company via an asset exchange with GSK, and Astra Zeneca shares surge on speculation that Pfizer is looking for a takeover. Joanna Partridge reports. Video provided by Reuters
Powered by NewsLook.com
How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) — NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com
How to Master Motherhood With the Best Work/Life Balance

How to Master Motherhood With the Best Work/Life Balance

TheStreet (Apr. 22, 2014) — In the U.S., there are more than 11 million couples trying to conceive at any given time. From helping celebrity moms like Bethanny Frankel to ordinary soon-to-be-moms, TV personality and parenting expert, Rosie Pope, gives you the inside scoop on mastering motherhood. London-born entrepreneur Pope is the creative force behind Rosie Pope Maternity and MomPrep. She explains why being an entrepreneur offers the best life balance for her and tips for all types of moms. Video provided by TheStreet
Powered by NewsLook.com
Catching More Than Fish: Ugandan Town Crippled by AIDS

Catching More Than Fish: Ugandan Town Crippled by AIDS

AFP (Apr. 22, 2014) — The village of Kasensero on the shores of Lake Victoria was where HIV-AIDS was first discovered in Uganda. Its transient population of fishermen and sex workers means the nationwide programme to combat the virus has had little impact. Duration: 02:30 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins