Since spring 2009, millions of Americans have been infected with the novel influenza A(H1N1) virus and thousands of people have died, according to background information in the article. Children have been particularly vulnerable to this strain, which in an unusual turn of events continued to spread and cause disease throughout the summer of 2009. "With large numbers of children from disparate locales coming together and living in communal settings, summer camps are uniquely suited to experience outbreaks of novel influenza A(H1N1) and potentially to contribute to the virus' ongoing spread during a period of the year when influenza typically is very uncommon," the authors write.

With rare exceptions, the H1N1 virus has retained sensitivity to the antiviral medication oseltamivir phosphate. The drug has been proven to prevent the spread of seasonal flu in settings such as households and nursing homes. David W. Kimberlin, M.D., of the University of Alabama at Birmingham, and colleagues described targeted use of this drug for containing the spread of H1N1 at a boys' camp in Alabama in July 2009.

A total of 171 campers, 48 camp counselors and 27 camp staff were involved in this program. Three campers tested positive for H1N1 during one of the camp's two-week sessions. These campers received oseltamivir and were immediately isolated and sent home. All campers and counselors in the infected child's adjoining cabins took oseltamivir prophylactically (to prevent infection) for 10 days.

"Alcohol-based hand sanitizer was provided at each of the daily activities, in the boys' cabins and in the dining hall, and counselors were educated by the medical staff on the spread of influenza and its prevention through good hand hygiene," the authors write. "All cabins, bathrooms and community sports equipment were sprayed or wiped down with disinfectant each day."

No additional campers, counselors or staff members became ill during the session and no campers tested positive for H1N1 after returning home. The three infected campers constituted an attack rate (the percentage of individuals who get sick out of the total population) of 1.8 percent.

The majority of staff and counselors (51 of 65, or 78 percent) and about 31 percent of campers experienced one or more adverse events, such as nausea, vomiting or headache, from the medication. However, none of the adverse events resulted in discontinuation of the therapy.

"In conjunction with aggressive hand sanitization and surface decontamination, a targeted approach to antiviral prophylaxis contained the spread of influenza in a summer camp setting," the authors conclude. "Additional controlled studies randomizing camps to specific components of the interventions used here would be needed to fully understand the relative benefits of each."

Note: If no author is given, the source is cited instead.

• Influenza
• Bird Flu
• Swine Flu
• Infectious Diseases
• Cold and Flu
• HIV and AIDS

• Flu vaccine
• Pandemic
• Influenza pandemic
• Antiviral drug
• Spanish flu
• Avian flu