Featured Research

from universities, journals, and other organizations

Nanomaterials may help fight cancer

Date:
February 12, 2010
Source:
DOE/Argonne National Laboratory
Summary:
Brain cancer is notoriously difficult to treat with standard cancer-fighting methods, so scientists have been looking outside standard medicine and into nanomaterials as a treatment alternative.

Still image from a video showing cancer cells self-destructing after being tagged with nanodiscs and exposed to a light magnetic field.
Credit: Image courtesy of DOE/Argonne National Laboratory

Scientists from the U.S. Department of Energy's Argonne National Laboratory and the University of Chicago Medical Center are shaking up the world of materials science and cancer research on the cover of the February 2010 issue of the journal Nature Materials.

Brain cancer is notoriously difficult to treat with standard cancer-fighting methods, so scientists have been looking outside standard medicine and into nanomaterials as a treatment alternative.

"Our mission is to develop advanced 'smart' materials with unique properties," said Elena Rozhkova, a nanoscientist with Argonne's Center for Nanoscale Materials. "These efforts are directed to the improvement of the national quality of life, including creating novel medical technologies."

A team of scientists, including Rozhkova, Dong-Hyum Kim, Valentyn Novosad, Tijana Rajh and Samuel Bader from Argonne, and Maciej Lesniak and Ilya Ulasov from the University of Chicago Brain Tumor Center, developed a technique that uses gold-plated iron-nickel microdiscs connected to brain-cancer-seeking antibodies to fight cancer. The microdiscs are an example of a nanomagnetic material and can be used to probe cell mechanics and activate mechanosensitive ion channels, as well as to advance cancer therapies.

The discs posses a spin-vortex ground state and sit dormant on the cancer cell until a small alternating magnetic field is applied and the vortices shift, creating an oscillation. The energy from the oscillation is transferred to the cell and triggers apoptosis, or "cell suicide."

Since the antibodies are attracted only to brain cancer cells, the process leaves surrounding healthy cells unharmed. This makes them unlike traditional cancer treatment methods, such as chemotherapy and radiation, which negatively affect both cancer and normal healthy cells.

"We are very excited about this melding of materials and life sciences, but we are still in the very early research stages," materials scientist Valentyn Novosad said. "We are planning to begin testing in animals soon, but we are several years away from human trials. Everything is still experimental."

Along with continued testing and research of the treatment, scientists also have to examine any possible side effects that have been so far unseen in the laboratory.

"The use of nanomaterials for cancer treatment is not a new concept, but the ability to kill the cells without harming surrounding healthy cells has incredible potential," Rozhkova said. "Such a topic can only be approached with the expertise of markedly differing disciplines such as physics, chemistry, biology and nanotechnology and can make a great impact in important areas of science and modern advanced technologies."


Story Source:

The above story is based on materials provided by DOE/Argonne National Laboratory. Note: Materials may be edited for content and length.


Cite This Page:

DOE/Argonne National Laboratory. "Nanomaterials may help fight cancer." ScienceDaily. ScienceDaily, 12 February 2010. <www.sciencedaily.com/releases/2010/02/100210211731.htm>.
DOE/Argonne National Laboratory. (2010, February 12). Nanomaterials may help fight cancer. ScienceDaily. Retrieved September 21, 2014 from www.sciencedaily.com/releases/2010/02/100210211731.htm
DOE/Argonne National Laboratory. "Nanomaterials may help fight cancer." ScienceDaily. www.sciencedaily.com/releases/2010/02/100210211731.htm (accessed September 21, 2014).

Share This



More Health & Medicine News

Sunday, September 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com
Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins