Featured Research

from universities, journals, and other organizations

Mayo Clinic reports its first lung transplantation by donation after cardiac death

Date:
February 18, 2010
Source:
Mayo Clinic
Summary:
Lung transplantation is a well-known therapy for patients with end-stage lung disease, but, as with other patients waiting for organs for transplantation, there are more recipients waiting than donors available. A potential solution for patients with end-stage lung disease is donation after cardiac death (DCD). Mayo Clinic reports its -- and Minnesota's -- first lung transplantation from DCD.

Lung transplantation is a well-known therapy for patients with end-stage lung disease, but, as with other patients waiting for organs for transplantation, there are more recipients waiting than donors available. A potential solution for patients with end-stage lung disease is donation after cardiac death (DCD). Mayo Clinic reports its -- and Minnesota's -- first lung transplantation from DCD in the February issue of Mayo Clinic Proceedings.

While brain death has become the most widely used criteria for organ donation over the past few decades, the earliest organ donations were from deceased donors following cardiac death, says Stephen Cassivi, M.D., Mayo Clinic thoracic surgeon and lead study author. "Today, our critical shortage of organs has brought about renewed interest in DCD organ procurement," he says. Few centers across the country perform DCD organ procurement for lung transplantation, and until recently only about 60 procedures have been done in the United States.

Mayo's first DCD lung transplantation was performed a year ago in a 59-year-old Illinois man who had alpha-1antitrypsin deficiency -- an inherited condition associated with emphysema. Emphysema is a type of chronic obstructive pulmonary disease, which includes a group of conditions that block airflow and make breathing difficult. He also was a former tobacco user.

Almost one year after his transplant, the recipient says he is doing well, walking about three or four miles a day. "I would not have made it through 2009 without the transplant, and today I am feeling better than I have in years and am able to be with my family," he says. "I feel very lucky and am grateful to my donor and his family."

Before his transplant, the patient's forced expiratory volume in the first second (FEV1) -- a measure of lung function and the ability to breathe -- was at 20 percent of normal, but at his appointment in January 2010, his FEV1 was at 103 percent, beyond normal, according to Dr. Cassivi. "He has made the absolute most of this gift," Dr. Cassivi says. "He's no longer confined to just sitting around. He is working his lungs and getting back to enjoying his life and the ability to breathe normally."

Transplantation made possible by DCD donors -- individuals who are declared dead according to criteria recommended in the Uniform Declaration of Death Act in the early 1980s -- expands the number of potential organs available to patients who desperately need organ transplants to live, Dr. Cassivi says. "As with our first patient in this report, we see this form of transplantation as a further needed opportunity to turn the inevitable tragedy for the donor and his or her loved ones into hope and life for transplant recipients," he says.


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Cite This Page:

Mayo Clinic. "Mayo Clinic reports its first lung transplantation by donation after cardiac death." ScienceDaily. ScienceDaily, 18 February 2010. <www.sciencedaily.com/releases/2010/02/100218125202.htm>.
Mayo Clinic. (2010, February 18). Mayo Clinic reports its first lung transplantation by donation after cardiac death. ScienceDaily. Retrieved July 28, 2014 from www.sciencedaily.com/releases/2010/02/100218125202.htm
Mayo Clinic. "Mayo Clinic reports its first lung transplantation by donation after cardiac death." ScienceDaily. www.sciencedaily.com/releases/2010/02/100218125202.htm (accessed July 28, 2014).

Share This




More Health & Medicine News

Monday, July 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Two Americans Contract Ebola in Liberia

Two Americans Contract Ebola in Liberia

Reuters - US Online Video (July 28, 2014) Two American aid workers in Liberia test positive for Ebola while working to combat the deadliest outbreak of the virus ever. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins