Featured Research

from universities, journals, and other organizations

Oscillations at odds in the heart

Date:
March 15, 2010
Source:
Rockefeller University Press
Summary:
Researchers show that a classical biological oscillator, the glycolytic oscillator, may increase damage to the heart during acute loss of oxygen (anoxia), and as may occur during ischemia.

Researchers in Germany show that a classical biological oscillator, the glycolytic oscillator, may increase damage to the heart during acute loss of oxygen (anoxia), and as may occur during ischemia. The study appears online March 15 in the Journal of General Physiology.

Related Articles


Oscillations are important in many biological processes, and life could not exist without them. They play roles in the cell cycle, the heart beat, circadian rhythms, and fertility cycles, to name a few. Although oscillations are vital for normal physiological functions, uncontrolled or irregular oscillations can have harmful effects. This may be true of glycolytic oscillations that occur during anoxia and ischemia in the heart.

Glycolytic oscillations have been studied in the past, but only in artificially induced conditions. Klaus Benndorf and his team from the University of Jena were able to create more clinically relevant conditions by using a technique that allowed a single isolated patch-clamped heart muscle cell to be imaged with fluorescent dyes during severe anoxia.

According to James Weiss and Jun-Hai Yang (UCLA) in a Commentary accompanying the paper, the next step will be to determine whether such metabolic oscillations can be detected during acute ischemia in the intact heart, and if so, whether they play a role in hastening cell death.


Story Source:

The above story is based on materials provided by Rockefeller University Press. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ganitkevich, V., V. Mattea, and K. Benndorf. Diffusion of a soluble protein, photoactivatable GFP, through a sensory cilium. J. Gen. Physiol, Feb 2010; 135: 173 - 196. DOI: 10.1085/jgp.200910322

Cite This Page:

Rockefeller University Press. "Oscillations at odds in the heart." ScienceDaily. ScienceDaily, 15 March 2010. <www.sciencedaily.com/releases/2010/03/100315103818.htm>.
Rockefeller University Press. (2010, March 15). Oscillations at odds in the heart. ScienceDaily. Retrieved March 1, 2015 from www.sciencedaily.com/releases/2010/03/100315103818.htm
Rockefeller University Press. "Oscillations at odds in the heart." ScienceDaily. www.sciencedaily.com/releases/2010/03/100315103818.htm (accessed March 1, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, March 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rehab Robot Helps Restore Damaged Muscles and Nerves

Rehab Robot Helps Restore Damaged Muscles and Nerves

Reuters - Innovations Video Online (Mar. 1, 2015) A rehabilitation robot prototype to help restore deteriorated nerves and muscles using electromyography and computer games. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
How Facebook Use Can Lead To Depression

How Facebook Use Can Lead To Depression

Newsy (Mar. 1, 2015) Margaret Duffy of the University of Missouri talks about her study on the social network and the envy and depression that Facebook use can cause. Video provided by Newsy
Powered by NewsLook.com
Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Reuters - Innovations Video Online (Feb. 27, 2015) A dongle that plugs into a Smartphone mimics a lab-based blood test for HIV and syphilis and can detect the diseases in 15 minutes, say researchers. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Doctor Says Head Transplants Possible Within Two Years

Doctor Says Head Transplants Possible Within Two Years

Buzz60 (Feb. 27, 2015) An Italian doctor is saying he could stick someone&apos;s head onto someone else&apos;s body. Patrick Jones (@Patrick_E_Jones) reports. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins