Featured Research

from universities, journals, and other organizations

Oscillations at odds in the heart

Date:
March 15, 2010
Source:
Rockefeller University Press
Summary:
Researchers show that a classical biological oscillator, the glycolytic oscillator, may increase damage to the heart during acute loss of oxygen (anoxia), and as may occur during ischemia.

Researchers in Germany show that a classical biological oscillator, the glycolytic oscillator, may increase damage to the heart during acute loss of oxygen (anoxia), and as may occur during ischemia. The study appears online March 15 in the Journal of General Physiology.

Related Articles


Oscillations are important in many biological processes, and life could not exist without them. They play roles in the cell cycle, the heart beat, circadian rhythms, and fertility cycles, to name a few. Although oscillations are vital for normal physiological functions, uncontrolled or irregular oscillations can have harmful effects. This may be true of glycolytic oscillations that occur during anoxia and ischemia in the heart.

Glycolytic oscillations have been studied in the past, but only in artificially induced conditions. Klaus Benndorf and his team from the University of Jena were able to create more clinically relevant conditions by using a technique that allowed a single isolated patch-clamped heart muscle cell to be imaged with fluorescent dyes during severe anoxia.

According to James Weiss and Jun-Hai Yang (UCLA) in a Commentary accompanying the paper, the next step will be to determine whether such metabolic oscillations can be detected during acute ischemia in the intact heart, and if so, whether they play a role in hastening cell death.


Story Source:

The above story is based on materials provided by Rockefeller University Press. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ganitkevich, V., V. Mattea, and K. Benndorf. Diffusion of a soluble protein, photoactivatable GFP, through a sensory cilium. J. Gen. Physiol, Feb 2010; 135: 173 - 196. DOI: 10.1085/jgp.200910322

Cite This Page:

Rockefeller University Press. "Oscillations at odds in the heart." ScienceDaily. ScienceDaily, 15 March 2010. <www.sciencedaily.com/releases/2010/03/100315103818.htm>.
Rockefeller University Press. (2010, March 15). Oscillations at odds in the heart. ScienceDaily. Retrieved March 27, 2015 from www.sciencedaily.com/releases/2010/03/100315103818.htm
Rockefeller University Press. "Oscillations at odds in the heart." ScienceDaily. www.sciencedaily.com/releases/2010/03/100315103818.htm (accessed March 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, March 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com
HIV Outbreak Prompts Public Health Emergency In Indiana

HIV Outbreak Prompts Public Health Emergency In Indiana

Newsy (Mar. 26, 2015) Indiana Gov. Mike Pence says he will bring additional state resources to help stop the epidemic. Video provided by Newsy
Powered by NewsLook.com
Indiana Permits Needle Exchange as HIV Cases Skyrocket

Indiana Permits Needle Exchange as HIV Cases Skyrocket

Reuters - US Online Video (Mar. 26, 2015) Governor Mike Pence declares the recent HIV outbreak in rural Indiana a "public health emergency" and authorizes a short-term needle-exchange program. Rough Cut (no reporter narration) Video provided by Reuters
Powered by NewsLook.com
AAA: Distracted Driving a Serious Teen Problem

AAA: Distracted Driving a Serious Teen Problem

AP (Mar. 25, 2015) While distracted driving is not a new problem for teens, new research from the AAA Foundation for Traffic Safety says it&apos;s much more serious than previously thought. (March 25) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins