Featured Research

from universities, journals, and other organizations

Potential new use for cancer treatment

Date:
April 6, 2010
Source:
University of York
Summary:
New research suggests anti-angiogenic drugs may help in the treatment of a range of diseases including visceral leishmaniasis.

Drugs increasingly used to treat cancer could have a major impact on a wide range of infectious diseases, according to new research.

Related Articles


Anti-angiogenic drugs are used to try and prevent cancers from stimulating the growth of the blood vessels they need to survive and grow.

New research by the Centre for Immunology and Infection at the University of York suggests the same drugs may help in the treatment of other diseases including visceral leishmaniasis which kills 70,000 people worldwide every year.

The findings, published online March 15 by the Journal of Clinical Investigation, show that anti-angiogenic drugs can improve the structure of tissues where immune responses are generated and which are often destroyed by chronic infection or inflammation.

The resulting improvement in the immune response can increase the effectiveness of conventional treatments for leishmaniasis, allowing doctors to use lower doses of existing drugs that otherwise have harmful side effects.

Professor Paul Kaye, Director of the Centre for Immunology and Infection, said: "While our research has focused on leishmaniasis the findings could have implications for a range of globally important diseases.

"It is particularly exciting that this potential has been discovered in a class of drugs that are already well-established in clinical practice.

"Our research also identifies ways that anti-angiogenic drugs might be used more effectively in the treatment of cancers."

The research was funded by the Medical Research Council and the Wellcome Trust.

These findings have led to further research, supported by Yorkshire Cancer Research, into the potential use of anti-angiogenic drugs as a "preconditioning agent" in the treatment of melanoma.

About Leishmaniasis

Leishmaniasis is a fly-borne disease caused by single-celled parasites called Leishmania. There are approximately 2 million cases of leishmaniasis per year in 88 countries worldwide, of which 500,000 are of the potentially fatal form of the disease (visceral leishmaniasis).


Story Source:

The above story is based on materials provided by University of York. Note: Materials may be edited for content and length.


Cite This Page:

University of York. "Potential new use for cancer treatment." ScienceDaily. ScienceDaily, 6 April 2010. <www.sciencedaily.com/releases/2010/03/100315172209.htm>.
University of York. (2010, April 6). Potential new use for cancer treatment. ScienceDaily. Retrieved April 18, 2015 from www.sciencedaily.com/releases/2010/03/100315172209.htm
University of York. "Potential new use for cancer treatment." ScienceDaily. www.sciencedaily.com/releases/2010/03/100315172209.htm (accessed April 18, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, April 18, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Our Love Of Puppy Dog Eyes Explained By Science

Our Love Of Puppy Dog Eyes Explained By Science

Newsy (Apr. 17, 2015) Researchers found a spike in oxytocin occurs in both humans and dogs when they gaze into each other&apos;s eyes. Video provided by Newsy
Powered by NewsLook.com
Scientists Find Link Between Gestational Diabetes And Autism

Scientists Find Link Between Gestational Diabetes And Autism

Newsy (Apr. 17, 2015) Researchers who analyzed data from over 300,000 kids and their mothers say they&apos;ve found a link between gestational diabetes and autism. Video provided by Newsy
Powered by NewsLook.com
Video Messages Help Reassure Dementia Patients

Video Messages Help Reassure Dementia Patients

AP (Apr. 17, 2015) Family members are prerecording messages as part of a unique pilot program at the Hebrew Home in New York. The videos are trying to help victims of Alzheimer&apos;s disease and other forms of dementia break through the morning fog of forgetfulness. (April 17) Video provided by AP
Powered by NewsLook.com
Boy or Girl? Intersex Awareness Is on the Rise

Boy or Girl? Intersex Awareness Is on the Rise

AP (Apr. 17, 2015) At least 1 in 5,000 U.S. babies are born each year with intersex conditions _ ambiguous genitals because of genetic glitches or hormone problems. Secrecy and surgery are common. But some doctors and activists are trying to change things. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins