Featured Research

from universities, journals, and other organizations

Lab on a chip: New technology facilitates studies of brain cells in stroke

Date:
March 22, 2010
Source:
Expertanswer
Summary:
A mini-laboratory that makes it possible, among other things, to study how brain cells in stroke patients are affected by lack of oxygen is under development. The lab-on-a-chip is expected to facilitate studies of all sorts of biological cells and how they are affected by different medicines, chemical substances, etc.

A mini-laboratory that makes it possible, among other things, to study how brain cells in stroke patients are affected by lack of oxygen is being developed by a research team at Luleĺ University of Technology (LTU) in Sweden. Lab on a Chip is what the scientists are calling their mini-lab, which is expected to facilitate studies of all sorts of biological cells and how they are affected by different medicines, chemical substances, etc.

Related Articles


The researchers in medical technology at Luleĺ University of Technology have wind in their sails. New technological solutions are needed to help meet Europe's rapidly growing needs for healthcare.

The development of the mini-lab Lab on a Chip is one of 22 projects being pursued within the framework of the Center for Medical Technology and Physics, CMTF, a joint initiative involving Luleĺ University of Technology and Umeĺ University.

Professor Olof Lindahl and his research associate Kerstin Ramser in Luleĺ are developing a so-called micro-flow system to study, for instance, how the vital oxygen-bearing protein neuroglobin, which is found in brain cells, is affected by the lack of oxygen that occurs in stroke.

Neuroglobin was discovered in 2000 by a German research team and occurs primarily in brain cells. Overproduction of neuroglobin in the brains of mice has been shown to mitigate the consequences of damage relating to oxygen deficiency in stroke.

"Today there are no really good methods for studying how individual cells signal under oxygen-poor conditions," says Kerstin Ramser. "One advantage of the new technology we use is that it is now possible to select and isolate specific cells in a controlled environment."

The Lab on a Chip that the Luleĺ researchers have produced measures 2 X 6 cm and fits on the specimen glass of a microscope. This makes it possible to reduce the size of the sample, in blood analysis, for example.

"What we are studying is the electrophysiological activity of brain cells, that is, their capacity to communicate with other cells under oxygen-poor and entirely oxygen-free conditions," says Kerstin Ramser.

To be able to study how brain cells are affected by stroke, researchers pump fluids with varying levels of oxygen content into channels in the mini-lab. The channels are extremely small, corresponding to one third of the thickness of a hair. Once the fluid has been pumped into the system, the cell sample is introduced. With the help of optical tweezers, which use laser beams to capture and move cells, the scientists can select and isolate a specific cell in order to study how it behaves in various oxygen mixtures.

"Enhance the quality of care today is largely a matter of developing new technologies that help us advance our knowledge of the major diseases, such as cancer, stroke, or Parkinson's," says Kerstin Ramser.

Their work is partly funded by EU Goal2.


Story Source:

The above story is based on materials provided by Expertanswer. Note: Materials may be edited for content and length.


Cite This Page:

Expertanswer. "Lab on a chip: New technology facilitates studies of brain cells in stroke." ScienceDaily. ScienceDaily, 22 March 2010. <www.sciencedaily.com/releases/2010/03/100322083652.htm>.
Expertanswer. (2010, March 22). Lab on a chip: New technology facilitates studies of brain cells in stroke. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2010/03/100322083652.htm
Expertanswer. "Lab on a chip: New technology facilitates studies of brain cells in stroke." ScienceDaily. www.sciencedaily.com/releases/2010/03/100322083652.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) — The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) — Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins