Featured Research

from universities, journals, and other organizations

Are periodontal disease and prostatitis linked?

Date:
April 28, 2010
Source:
Case Western Reserve University
Summary:
Are prostate problems, which impact 8 percent of the population, associated with poor oral health? Researchers report initial results from a small sample that inflammation from gum disease and prostate problems just might be linked.

Researchers from Case Western Reserve University School of Dental Medicine and University Hospitals Case Medical Center report initial results from a small sample that inflammation from gum disease and prostate problems just might be linked. They discuss their new evidence in the Journal of Periodontology, the official journal of the American Academy of Periodontology.

Related Articles


The researchers compared two markers: the prostate-specific antigen (PSA) used to measure inflammation levels in prostate disease, and clinical attachment level (CAL) of the gums and teeth, which can be an indicator for periodontitis.

A PSA elevation of 4.0 ng/ml in the blood can be a sign of inflammation or malignancy. Patients with healthy prostate glands have lower than 4.0ng/ml levels. A CAL number greater than 2.7 mm indicates periodontitis.

Like prostatitis, periodontitis also produces high inflammation levels.

"Subjects with both high CAL levels and moderate to severe prostatitis have higher levels of PSA or inflammation," stated Nabil Bissada, chair of the department of periodontics in the dental school.

Bissada added that this might explain why PSA levels can be high in prostatitis, but sometimes cannot be explained by what is happening in the prostate glands.

"It is something outside the prostate gland that is causing an inflammatory reaction," he said.

Because periodontitis has been linked to heart disease, diabetes and rheumatoid arthritis, the researchers felt a link might exist to prostate disease.

Thirty-five men from a sample of 150 patients qualified for the study, funded by the department of periodontology at the dental school. The participants were selected from patients at the University Hospitals Case Medical Center with mild to severe prostatitis, who had undergone needle biopsies and were found to have inflammation and in some patients, malignancies.

The participants were divided into two groups: those with high PSA levels for moderate or severe prostatitis or a malignancy and those with PSA levels below 4 ng/ml. All had not had dental work done for at least three months and were given an examination to measure the gum health.

Looking at the results, the researchers from the dental school and the department of urology and the Institute of Pathology at the hospital found those with the most severe form of the prostatitis also showed signs for periodontitis.

Other authors on the paper, "Association between Periodontal Disease and Prostate-Specific Antigen Levels in Chronic Prostatitis Patients," were: Nishant Joshi, Sena Narendran, Rick Jurevic and Robert Skillicorn from the CWRU dental school; and Donald Bodner and Gregory T. MacLennon from the University Hospitals Case Medical Center.


Story Source:

The above story is based on materials provided by Case Western Reserve University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Joshi et al. Association Between Periodontal Disease and Prostate Specific Antigen Levels in Chronic Prostatitis Patients. Journal of Periodontology, 2010; 100409084221025 DOI: 10.1902/jop.2010.090646

Cite This Page:

Case Western Reserve University. "Are periodontal disease and prostatitis linked?." ScienceDaily. ScienceDaily, 28 April 2010. <www.sciencedaily.com/releases/2010/04/100426141502.htm>.
Case Western Reserve University. (2010, April 28). Are periodontal disease and prostatitis linked?. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2010/04/100426141502.htm
Case Western Reserve University. "Are periodontal disease and prostatitis linked?." ScienceDaily. www.sciencedaily.com/releases/2010/04/100426141502.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins