Featured Research

from universities, journals, and other organizations

A risk factor of gallstone formation after radical gastrectomy

Date:
June 2, 2010
Source:
World Journal of Gastroenterology
Summary:
The incidence of gallstones is higher in patients after radical gastrectomy than in the general population. The current literature suggests that this higher incidence is related to gallbladder motility disorder after surgery. A research group in China investigated the association between the XbaI polymorphisms of APOB gene and gallstone formation after gastrectomy. Patient with the X+ allele of APOB gene was found to be another important risk factor of gallstone formation after radical gastrectomy.

The cause of higher incidence of gallstone after radical gastrectomy still remains unknown. Almost all previous studies have attributed gallstone formation to gallbladder motility disorder after gastrectomy, But this theory cannot completely explain it. Is there any other risk factor of gallstone formation after gastrectomy?

A research article to be published on May 28, 2010 in the World Journal of Gastroenterology addresses this question.

The research team led by Professor Niu from Zhongshan Hospital of Fudan University enrolled 206 patients between January 2005 and December 2006, who underwent radical gastrectomy for gastric cancer. These patients were grouped according to XbaI polymorphisms of APOB gene. After at least 2 years follow up, they found that the incidence of gallstone following gastrectomy was significiantly higher in patients with the X+ allele of APOB gene, who have a higher concentration of TC and LDL.

These results demonstrate that the X+ allele may influence the levels of TC and LDL, resulting in an increased saturation of bile cholesterol, leading to the gallstone formation after gastrectomy. The authors believe besides the gallbladder motility disorder, X+ allele of APOB gene is another important risk factor of gallstone formation after gastrectomy.


Story Source:

The above story is based on materials provided by World Journal of Gastroenterology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Liu FL, Lu WB, Niu WX. Xba%u2160 polymorphisms of apolipoprotein B gene: Another risk factor of gallstone formation after radical gastrectomy. World J Gastroenterol, 2010; 16 (20): 2549-2553 [link]

Cite This Page:

World Journal of Gastroenterology. "A risk factor of gallstone formation after radical gastrectomy." ScienceDaily. ScienceDaily, 2 June 2010. <www.sciencedaily.com/releases/2010/06/100602095048.htm>.
World Journal of Gastroenterology. (2010, June 2). A risk factor of gallstone formation after radical gastrectomy. ScienceDaily. Retrieved September 3, 2014 from www.sciencedaily.com/releases/2010/06/100602095048.htm
World Journal of Gastroenterology. "A risk factor of gallstone formation after radical gastrectomy." ScienceDaily. www.sciencedaily.com/releases/2010/06/100602095048.htm (accessed September 3, 2014).

Share This



More Health & Medicine News

Wednesday, September 3, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Snack Attack: Study Says Action Movies Make You Snack More

Snack Attack: Study Says Action Movies Make You Snack More

Newsy (Sep. 2, 2014) You're more likely to gain weight while watching action flicks than you are watching other types of programming, says a new study published in JAMA. Video provided by Newsy
Powered by NewsLook.com
U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

Newsy (Sep. 2, 2014) The U.N. says the problem is two-fold — quarantine zones and travel restrictions are limiting the movement of both people and food. Video provided by Newsy
Powered by NewsLook.com
Doctors Fear They're Losing Battle Against Ebola

Doctors Fear They're Losing Battle Against Ebola

AP (Sep. 2, 2014) As a third American missionary is confirmed to have contracted Ebola in Liberia, doctors on the ground in West Africa fear they're losing the battle against the outbreak. (Sept. 2) Video provided by AP
Powered by NewsLook.com
Tech Giants Bet on 3D Headsets for Gaming, Healthcare

Tech Giants Bet on 3D Headsets for Gaming, Healthcare

AFP (Sep. 2, 2014) When Facebook acquired the virtual reality hardware developer Oculus VR in March for $2 billion, CEO Mark Zuckerberg hailed the firm's technology as "a new communication platform." Duration: 02:24 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins