Featured Research

from universities, journals, and other organizations

Molecular imaging prototype looks deep into soft tissues of the brain and other organs

Date:
June 10, 2010
Source:
Society of Nuclear Medicine
Summary:
Research points to the possibility of a new hybrid molecular imaging system that uses single photon emission tomography (SPECT) and magnetic resonance technology (MR). The new technology could provide a greater depth of information about an array of biological processes and anatomical information including soft-tissue contrast, which is important for many diagnoses.

Research unveiled at the Society of Nuclear Medicine's 57th Annual Meeting points to the possibility of a new hybrid molecular imaging system that uses single photon emission tomography (SPECT) and magnetic resonance technology (MR). The new technology could provide a greater depth of information about an array of biological processes and anatomical information including soft-tissue contrast, which is important for many diagnoses.

Related Articles


"By combining SPECT and MR imaging in a single scan, researchers can acquire fused images that provide meaningful information for brain studies, heart imaging and a range of other applications," said Benjamin M. W. Tsui, Ph.D., lead researcher and professor of radiology at Johns Hopkins University, Baltimore, Md. "Imaging the human brain using this technique could revolutionize diagnostic radiology and improve patient care."

Previous studies have been conducted for the development of other hybrid molecular imaging systems that combine positron emission tomography (PET) and MR, but this is the first study evaluating the feasibility of a SPECT/MR system. The introduction of MR to SPECT imaging not only adds useful anatomical and biochemical information, but it would also help to compensate for other image degrading factors, such as photon attenuation and scatter, which can be present in SPECT imaging.

The research team developed a fully MR-compatible, stationary ring-type SPECT prototype using cadmium zinc telluride (CZT) solid-state detector modules. All components used for the new preclinical SPECT system were entirely composed of non-ferrous materials to avoid image artifacts that could otherwise occur within the magnetic field. In this study, researchers did not have to rotate the SPECT component, but the imaging scanner was able to capture dynamic data using multiple projection views. Researchers also investigated image reconstruction methods that would best work with data acquired from the new imaging system. This study proves that SPECT/MR is a viable technology that could enhance the diagnostic capability of SPECT alone and provide additional information that SPECT/CT cannot. Plans to extend the preclinical prototype to clinical brain SPECT/MR are underway and clinical trials are expected to begin within three or four years.

Dr. Tsui's research group for this study was part of a collaboration that included the University of California, Irvine, and was led by Gamma Medica-Ideas, Northridge, Calif., under the support of an NIH SBIR research grant -- NIH NIBIB Small Business Innovative Research Grant R44EB006712.

Scientific Paper 409: B.M. Tsui, J. Xu, S. Chen, J. Yu, Radiology, Johns Hopkins Medical Institutions, Baltimore, Md.; D. Meier, B.E. Patt, D.J. Wagenaar, Gamma Medica-Ideas, Inc., Northridge, Calif.; "The application of a compact MR-compatible SPECT system for small animal SPECT/MR imaging and tracer kinetics studies," SNM's 57th Annual Meeting, June 5-9, 2010, Salt Lake City, Utah.


Story Source:

The above story is based on materials provided by Society of Nuclear Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Society of Nuclear Medicine. "Molecular imaging prototype looks deep into soft tissues of the brain and other organs." ScienceDaily. ScienceDaily, 10 June 2010. <www.sciencedaily.com/releases/2010/06/100607142005.htm>.
Society of Nuclear Medicine. (2010, June 10). Molecular imaging prototype looks deep into soft tissues of the brain and other organs. ScienceDaily. Retrieved November 1, 2014 from www.sciencedaily.com/releases/2010/06/100607142005.htm
Society of Nuclear Medicine. "Molecular imaging prototype looks deep into soft tissues of the brain and other organs." ScienceDaily. www.sciencedaily.com/releases/2010/06/100607142005.htm (accessed November 1, 2014).

Share This



More Health & Medicine News

Saturday, November 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins