Featured Research

from universities, journals, and other organizations

Molecular imaging prototype looks deep into soft tissues of the brain and other organs

Date:
June 10, 2010
Source:
Society of Nuclear Medicine
Summary:
Research points to the possibility of a new hybrid molecular imaging system that uses single photon emission tomography (SPECT) and magnetic resonance technology (MR). The new technology could provide a greater depth of information about an array of biological processes and anatomical information including soft-tissue contrast, which is important for many diagnoses.

Research unveiled at the Society of Nuclear Medicine's 57th Annual Meeting points to the possibility of a new hybrid molecular imaging system that uses single photon emission tomography (SPECT) and magnetic resonance technology (MR). The new technology could provide a greater depth of information about an array of biological processes and anatomical information including soft-tissue contrast, which is important for many diagnoses.

Related Articles


"By combining SPECT and MR imaging in a single scan, researchers can acquire fused images that provide meaningful information for brain studies, heart imaging and a range of other applications," said Benjamin M. W. Tsui, Ph.D., lead researcher and professor of radiology at Johns Hopkins University, Baltimore, Md. "Imaging the human brain using this technique could revolutionize diagnostic radiology and improve patient care."

Previous studies have been conducted for the development of other hybrid molecular imaging systems that combine positron emission tomography (PET) and MR, but this is the first study evaluating the feasibility of a SPECT/MR system. The introduction of MR to SPECT imaging not only adds useful anatomical and biochemical information, but it would also help to compensate for other image degrading factors, such as photon attenuation and scatter, which can be present in SPECT imaging.

The research team developed a fully MR-compatible, stationary ring-type SPECT prototype using cadmium zinc telluride (CZT) solid-state detector modules. All components used for the new preclinical SPECT system were entirely composed of non-ferrous materials to avoid image artifacts that could otherwise occur within the magnetic field. In this study, researchers did not have to rotate the SPECT component, but the imaging scanner was able to capture dynamic data using multiple projection views. Researchers also investigated image reconstruction methods that would best work with data acquired from the new imaging system. This study proves that SPECT/MR is a viable technology that could enhance the diagnostic capability of SPECT alone and provide additional information that SPECT/CT cannot. Plans to extend the preclinical prototype to clinical brain SPECT/MR are underway and clinical trials are expected to begin within three or four years.

Dr. Tsui's research group for this study was part of a collaboration that included the University of California, Irvine, and was led by Gamma Medica-Ideas, Northridge, Calif., under the support of an NIH SBIR research grant -- NIH NIBIB Small Business Innovative Research Grant R44EB006712.

Scientific Paper 409: B.M. Tsui, J. Xu, S. Chen, J. Yu, Radiology, Johns Hopkins Medical Institutions, Baltimore, Md.; D. Meier, B.E. Patt, D.J. Wagenaar, Gamma Medica-Ideas, Inc., Northridge, Calif.; "The application of a compact MR-compatible SPECT system for small animal SPECT/MR imaging and tracer kinetics studies," SNM's 57th Annual Meeting, June 5-9, 2010, Salt Lake City, Utah.


Story Source:

The above story is based on materials provided by Society of Nuclear Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Society of Nuclear Medicine. "Molecular imaging prototype looks deep into soft tissues of the brain and other organs." ScienceDaily. ScienceDaily, 10 June 2010. <www.sciencedaily.com/releases/2010/06/100607142005.htm>.
Society of Nuclear Medicine. (2010, June 10). Molecular imaging prototype looks deep into soft tissues of the brain and other organs. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2010/06/100607142005.htm
Society of Nuclear Medicine. "Molecular imaging prototype looks deep into soft tissues of the brain and other organs." ScienceDaily. www.sciencedaily.com/releases/2010/06/100607142005.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins