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Incidence and reproduction numbers of pertussis

Date:
June 22, 2010
Source:
Public Library of Science
Summary:
Analyses of serological and social contact data from five European countries show that childhood vaccination against Bordetella pertussis (whooping cough) has shifted the burden of infection from children to adolescents and adults.
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Analyses of serological and social contact data from five European countries by Mirjam Kretzschmar and colleagues show that childhood vaccination against Bordetella pertussis (whooping cough) has shifted the burden of infection from children to adolescents and adults. Adolescents and adults rarely develop severe pertussis.

The research appears in PLoS Medicine, published by the Public Library of Science.

Two new statistical methods were used to estimate the incidence and basic reproduction number of pertussis. The authors used cross-sectional data on the seroprevalance of antibodies to pertussis toxin and cross-sectional data on social contact patterns from 5 countries. The results of this study suggest that in countries with high childhood vaccine coverage, adolescents and young adults are reservoirs for asymptomatic pertussis infection.

The researchers suggest pertussis could be eliminated if a vaccine or vaccine schedule could be developed that provided life-long protection against pertussis.


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The above post is reprinted from materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Kretzschmar M, Teunis PFM, Pebody RG (2010) . PLoS Med 7 (6): e1000291. doi:. Incidence and Reproduction Numbers of Pertussis: Estimates from Serological and Social Contact Data in Five European Countries. PLoS Medicine, 2010; DOI: 10.1371/journal.pmed.1000291

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Public Library of Science. "Incidence and reproduction numbers of pertussis." ScienceDaily. ScienceDaily, 22 June 2010. <www.sciencedaily.com/releases/2010/06/100622175506.htm>.
Public Library of Science. (2010, June 22). Incidence and reproduction numbers of pertussis. ScienceDaily. Retrieved August 4, 2015 from www.sciencedaily.com/releases/2010/06/100622175506.htm
Public Library of Science. "Incidence and reproduction numbers of pertussis." ScienceDaily. www.sciencedaily.com/releases/2010/06/100622175506.htm (accessed August 4, 2015).

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