Featured Research

from universities, journals, and other organizations

Is it safe for endoscopic piecemeal mucosal resection in treating large sessile colorectal polyps?

Date:
June 24, 2010
Source:
World Journal of Gastroenterology
Summary:
Endoscopic removal of colonic adenomatous polyps is a commonly used technique that reduces the incidence of colorectal cancer. A research group at the National Cancer Center, Korea revealed that endoscopic piecemeal mucosal resection can be used safely for large sessile colorectal polyps, but should be applied carefully in malignant polyps due to high recurrence rate.

Endoscopic resection of large sessile colorectal polyps is increasingly used as an alternative to surgery, but remains challenging because of its technical difficulty, the high risk of complications such as bleeding or perforation, and the possibility of coexisting malignancy.

This research, lead by Dr. Sohn DK and his colleagues at the National Cancer Center, Korea, demonstrated the safety of endoscopic piecemeal resection (EPMR) for large sessile colorectal polyps and the research has recently been published on June 14, 2010 in the World Journal of Gastroenterology. The authors included a large number of polyps with significant numbers of malignancies and were able to demonstrate that relapse was low in patients with benign polyps after endoscopic resection.

The research group enrolled 47 patients with 50 large sessile polyps (2 cm or greater in diameter) who underwent EPMR using a submucosal saline injection technique and observed them during follow-up examinations over a median period of 37 months. They showed that 12% of patients had procedure-related minor bleeding. No perforations were observed. Recurrence was identified in 5 cases (12.2%). The significant finding of this research is that the incidence of recurrence after EPMR in malignant lesions was higher than that in benign lesions (33.3% vs 3.1%).

It is still difficult to explain the reason why the incidence of recurrence after EPMR in malignant lesions was higher than that in benign lesions. However, the authors suggested that the endoscopist should try to remove all cancer cells completely because microscopic residual cancer cells after EPMR can cause recurrences. They also suggested that EPMR should be applied carefully in malignant polyps, and close follow-up endoscopic examinations are necessary for early detection of recurrence.


Story Source:

The above story is based on materials provided by World Journal of Gastroenterology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Seo GJ, Sohn DK, Han KS, Hong CW, Kim BC, Park JW, Choi HS, Chang HJ, Oh JH. Recurrence after endoscopic piecemeal mucosal resection for large sessile colorectal polyps. World Journal of Gastroenterology, 2010; 16 (22): 2806 DOI: 10.3748/wjg.v16.i22.2806

Cite This Page:

World Journal of Gastroenterology. "Is it safe for endoscopic piecemeal mucosal resection in treating large sessile colorectal polyps?." ScienceDaily. ScienceDaily, 24 June 2010. <www.sciencedaily.com/releases/2010/06/100624104526.htm>.
World Journal of Gastroenterology. (2010, June 24). Is it safe for endoscopic piecemeal mucosal resection in treating large sessile colorectal polyps?. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/2010/06/100624104526.htm
World Journal of Gastroenterology. "Is it safe for endoscopic piecemeal mucosal resection in treating large sessile colorectal polyps?." ScienceDaily. www.sciencedaily.com/releases/2010/06/100624104526.htm (accessed April 24, 2014).

Share This



More Health & Medicine News

Thursday, April 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Fungus Killing Bats, Spreading in US

Deadly Fungus Killing Bats, Spreading in US

AP (Apr. 24, 2014) A disease that has killed more than six million cave-dwelling bats in the United States is on the move and wildlife biologists are worried. White Nose Syndrome, discovered in New York in 2006, has now spread to 25 states. (April 24) Video provided by AP
Powered by NewsLook.com
Companies Ramp Up Wellness to Lower Health Costs

Companies Ramp Up Wellness to Lower Health Costs

AP (Apr. 24, 2014) That little voice telling you to exercise, get in shape and get healthy is probably coming from your boss. More companies are beefing up wellness programs to try and cut down their health care costs. (April 24) Video provided by AP
Powered by NewsLook.com
Blood From World's Oldest Woman Suggests Life Limit

Blood From World's Oldest Woman Suggests Life Limit

Newsy (Apr. 24, 2014) Scientists say for the extremely elderly, their stem cells might reach a state of exhaustion. This could limit one's life span. Video provided by Newsy
Powered by NewsLook.com
FDA Wants To Ban Sales Of E-Cigarettes To Minors

FDA Wants To Ban Sales Of E-Cigarettes To Minors

Newsy (Apr. 24, 2014) The Food and Drug Administration wants to crack down on the use of e-cigarettes, banning the sale of the product to minors. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins