Featured Research

from universities, journals, and other organizations

Can too much HDL be harmful to women with type 1 diabetes?

Date:
June 29, 2010
Source:
University of Pittsburgh Schools of the Health Sciences
Summary:
Elevated blood levels of high-density lipoprotein (HDL) or "good" cholesterol, typically thought to protect against heart disease, may do the opposite in women with type 1 diabetes, according to new research.

Elevated blood levels of high-density lipoprotein (HDL) or "good" cholesterol, typically thought to protect against heart disease, may do the opposite in women with type 1 diabetes, according to a University of Pittsburgh Graduate School of Public Health study being presented at the 70th Scientific Sessions of the American Diabetes Association.

Related Articles


The study, abstract number 0098-OR, included 658 men and women enrolled in the Pittsburgh Epidemiology of Diabetes Complications Study, a long-term prospective examination of childhood onset type 1 diabetes that began in 1986. Participants were diagnosed with type 1 diabetes between 1950 and 1980.

HDL cholesterol is known as "good" cholesterol because it helps prevent arteries from becoming clogged. High levels of HDL cholesterol, over 60 milligrams per deciliter (mg/dL), generally protect against heart disease, while low levels (less than 40 mg/dL for men and less than 50 mg/dL for women) increase risk.

Study researchers found the incidence of heart disease increased in both men and women with diabetes who had lower levels of HDL -- below 47.5 mg/dL. For men, as levels of HDL increased, their incidence of heart disease decreased. The same was found for women, except in those with very high levels of HDL (over 80 mg/dL) whose incidence of heart disease increased substantially. Study authors were unable to draw a meaningful comparison to male participants since only a few had HDL over 80 mg/dL.

"Although high levels of HDL are typically associated with decreased risk for cardiovascular disease, this may not be the case for women who have type 1 diabetes and HDL in the upper ranges," said Tina Costacou, Ph.D., lead author of the study and assistant professor of epidemiology, University of Pittsburgh Graduate School of Public Health. "We need to examine this relationship further, but our study suggests that too much of a good thing may not always offer protection and may even be harmful for women with type 1 diabetes."

Study co-authors include Rhobert Evans, Ph.D., and Trevor Orchard, M.D., of the University of Pittsburgh. The study was funded by the National Institutes of Health.


Story Source:

The above story is based on materials provided by University of Pittsburgh Schools of the Health Sciences. Note: Materials may be edited for content and length.


Cite This Page:

University of Pittsburgh Schools of the Health Sciences. "Can too much HDL be harmful to women with type 1 diabetes?." ScienceDaily. ScienceDaily, 29 June 2010. <www.sciencedaily.com/releases/2010/06/100627093608.htm>.
University of Pittsburgh Schools of the Health Sciences. (2010, June 29). Can too much HDL be harmful to women with type 1 diabetes?. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2010/06/100627093608.htm
University of Pittsburgh Schools of the Health Sciences. "Can too much HDL be harmful to women with type 1 diabetes?." ScienceDaily. www.sciencedaily.com/releases/2010/06/100627093608.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins