Featured Research

from universities, journals, and other organizations

Painkillers not linked with heart disease in elderly patients and may protect against death, study finds

Date:
July 11, 2010
Source:
University of Aberdeen
Summary:
Commonly used painkillers like ibuprofen do not increase the risk of heart attack in the elderly population, according to a new study.

Commonly used painkillers like ibuprofen do not increase the risk of heart attack in the elderly population, according to a new study.

Researchers found that the use of these drugs -- also called non-steroidal anti-inflammatory drugs (NSAIDs) -- was also associated with a lower risk of death although they are not sure why.

Their findings -- which appear in the British Journal of Clinical Pharmacology -- were based on a study which looked at a nationwide hospital admission and pharmacy prescription database of 320,000 Australian veterans.

Researchers looked at anti-inflammatory drugs that -- with the exception of ibuprofen -- generally require a prescription.

Professor Arduino Mangoni, who recently joined the University of Aberdeen from Flinders University in Adelaide, led the study which was conducted in Australia and funded by the Department of Veterans' Affairs.

He said: "Heart disease represents one of the main causes of death and long-term disability in the elderly population and the burden of heart disease is likely to increase in the future due to the progressive ageing of the population.

"Thinking up until now suggests that the use of anti-inflammatory drugs, for the management of pain and inflammation in a number of disorders affecting the musculoskeletal system, increases the risk of heart disease. Concerns over the potential risk associated with the use of NSAIDs have been expressed in a recent statement by the American Heart Association.

"However, the evidence of a link between NSAIDs and heart disease is controversial as several studies have failed to demonstrate a significant increase in the risk.

"The existing controversy surrounding the association between NSAIDs and heart disease prompted this large-scale Australian study.

"Unlike previous studies we did not observe an increased risk of heart disease after considering NSAIDs as a whole, their sub-classes, and several individual drugs.

"In fact our study has demonstrated that the use of NSAIDs has overall a neutral effect on the risk of heart disease in a large elderly population with multiple co-existing medical conditions.

"We also noted that the use of NSAIDs was associated with a reduction in all-cause mortality and there was a clear association with the number of prescriptions supplied in that the higher the number of prescriptions for NSAIDs the lower the risk of death."

Professor Mangoni , Chair in Medicine of Old Age at the University of Aberdeen, believes the link between NSAIDs and mortality could be due to a number of factors.

"It could be that anti-inflammatory drugs could exert some protective effects towards heart disease and cancer, the two main killers in our ageing population. It might be that people on these drugs have better pain control and therefore have a less sedentary lifestyle. Or perhaps people on these drugs in our study were maybe generally healthier."

Despite the findings Professor Mangoni would not advise people to take painkillers regularly unless they are necessary.

"Further prospective studies are urgently required to investigate the impact of NSAID use on these outcomes and the mechanisms involved."


Story Source:

The above story is based on materials provided by University of Aberdeen. Note: Materials may be edited for content and length.


Cite This Page:

University of Aberdeen. "Painkillers not linked with heart disease in elderly patients and may protect against death, study finds." ScienceDaily. ScienceDaily, 11 July 2010. <www.sciencedaily.com/releases/2010/07/100707065216.htm>.
University of Aberdeen. (2010, July 11). Painkillers not linked with heart disease in elderly patients and may protect against death, study finds. ScienceDaily. Retrieved September 22, 2014 from www.sciencedaily.com/releases/2010/07/100707065216.htm
University of Aberdeen. "Painkillers not linked with heart disease in elderly patients and may protect against death, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/07/100707065216.htm (accessed September 22, 2014).

Share This



More Health & Medicine News

Monday, September 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com
Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins