Featured Research

from universities, journals, and other organizations

Adolescents with type 2 diabetes have diminished cognitive performance and brain abnormalities, study finds

Date:
August 2, 2010
Source:
NYU Langone Medical Center / New York University School of Medicine
Summary:
Researchers have found that obese adolescents with type 2 diabetes have diminished cognitive performance and subtle abnormalities in the brain as detected by magnetic resonance imaging. Identification of cognitive impairments as a complication of type 2 diabetes emphasizes the importance of addressing issues of inactivity and obesity, two important risk factors for the development of the disease among the young.

A study by researchers at NYU Langone Medical Center have found that obese adolescents with type 2 diabetes have diminished cognitive performance and subtle abnormalities in the brain as detected by Magnetic Resonance Imaging (MRI). Identification of cognitive impairments as a complication of type 2 diabetes emphasizes the importance of addressing issues of inactivity and obesity, two important risk factors for the development of the disease among the young.

Related Articles


The study appeared online in the journal Diabetologia, July 30, 2010.

"This is the first study that shows that children with type 2 diabetes have more cognitive dysfunction and brain abnormalities than equally obese children who did not yet have marked metabolic dysregulation from their obesity, " says Antonio Convit, MD, professor of Psychiatry and Medicine at NYU Langone Medical Center and the Nathan S. Kline Institute for Psychiatric Research. "The findings are significant because they indicate that insulin resistance from obesity is lowering children's cognitive performance, which may be affecting their ability to perform well in school."

Researchers studied 18 obese adolescents with type 2 diabetes and compared them to equally obese adolescents from the same socioeconomic and ethnic background but without evidence of marked insulin resistance or pre-diabetes. Investigators found that adolescents with type 2 diabetes not only had significant reductions in performance on tests that measure overall intellectual functioning, memory, and spelling, which could affect their school performance, but also had clear abnormalities in the integrity of the white matter in their brains.

"We have previously found brain abnormalities in adults with Type 2 diabetes, but believed those changes might have been a result of vascular disease," adds Dr. Convit. "Now we see that subtle changes in white matter of the brain in adolescents may be a result of the abnormal physiology that accompanies type 2 diabetes. If we can improve insulin sensitivity and help children through exercise and weight loss, perhaps we can reverse these deficits."

Co-authors of the study include P.L. Yau, W.H. Tsui, B.A. Ardekani of NYU Langone Medical Center and the Nathan S. Klein Institute for Psychiatric Research.


Story Source:

The above story is based on materials provided by NYU Langone Medical Center / New York University School of Medicine. Note: Materials may be edited for content and length.


Journal Reference:

  1. P. L. Yau, D. C. Javier, C. M. Ryan, W. H. Tsui, B. A. Ardekani, S. Ten and A. Convit. Preliminary evidence for brain complications in obese adolescents with type 2 diabetes mellitus. Diabetologia, 2010; DOI: 10.1007/s00125-010-1857-y

Cite This Page:

NYU Langone Medical Center / New York University School of Medicine. "Adolescents with type 2 diabetes have diminished cognitive performance and brain abnormalities, study finds." ScienceDaily. ScienceDaily, 2 August 2010. <www.sciencedaily.com/releases/2010/08/100802125823.htm>.
NYU Langone Medical Center / New York University School of Medicine. (2010, August 2). Adolescents with type 2 diabetes have diminished cognitive performance and brain abnormalities, study finds. ScienceDaily. Retrieved November 1, 2014 from www.sciencedaily.com/releases/2010/08/100802125823.htm
NYU Langone Medical Center / New York University School of Medicine. "Adolescents with type 2 diabetes have diminished cognitive performance and brain abnormalities, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/08/100802125823.htm (accessed November 1, 2014).

Share This



More Health & Medicine News

Saturday, November 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins