Featured Research

from universities, journals, and other organizations

Alcohol intake increases certain types of breast cancer, study finds

Date:
August 24, 2010
Source:
Journal of the National Cancer Institute
Summary:
Alcohol increases the risk of lobular and hormone receptor-positive breast cancer, but not necessarily invasive ductal carcinomas, according to a new study.

Alcohol increases the risk of lobular and hormone receptor-positive breast cancer, but not necessarily invasive ductal carcinomas, according to a study published August 23 online in The Journal of the National Cancer Institute.

Although alcohol intake is an established risk factor for overall breast cancer, few studies have looked at the relationship between alcohol use and breast cancer risk by subtype of breast cancer. While some studies have shown alcohol use is more strongly related to risk of hormone receptor-positive (estrogen receptor and/or progesterone receptor-positive) breast cancer, not many have looked at breast cancer risk by histology, or whether a tumor is ductal -- in the milk ducts -- or lobular -- in the milk-producing lobules.

To understand how alcohol may influence sub-types of breast cancer, Christopher I. Li, M.D., Ph.D., and colleagues at Fred Hutchinson Cancer Research Center conducted an observational study of a subset of patients in the Women's Health Initiative (WHI) study, conducted between 1993 and 1998, which included 87,724 postmenopausal women aged 50-79 years.

The researchers looked at the following data from the 2,944 women in the WHI study who developed invasive breast cancer: tumor subtypes and hormone status, alcohol consumption, demographic and lifestyle characteristics, family history of diseases and reproductive history. Women were categorized as those who never drank, those who formerly drank and those who currently drank. Drinkers were grouped into six categories according to the average number of drinks per week, starting from less than one drink per week to more than 14 drinks per week.

The researchers found that alcohol use is more strongly related to the risk of lobular carcinoma than ductal carcinoma, and more strongly related to hormone-receptor- positive breast cancer than hormone-receptor-negative breast cancer. These results confirm previous findings of an association of alcohol consumption with hormone-positive breast cancer risk, as well as three previous case control studies that identified a stronger association of alcohol with lobular carcinoma. The risks observed did not vary by the type of alcohol women consumed.

The authors write, "We found that women who drank one or more drinks per day had about double the risk of lobular type breast cancer, but no increase in their risk of ductal type breast cancer. It is important to note that ductal cancer is much more common than lobular cancer accounting for about 70 percent of all breast cancers whereas lobular cancer accounts for only about 10-15 percent of cases."

The study's primary limitation, the authors say, is that alcohol usage was only assessed at the beginning of the study, so the researchers had no information on womens' past alcohol usage, nor their subsequent usage.


Story Source:

The above story is based on materials provided by Journal of the National Cancer Institute. Note: Materials may be edited for content and length.


Journal Reference:

  1. Christopher I. Li, Rowan T. Chlebowski, Matthew Freiberg, Karen C. Johnson, Lewis Kuller, Dorothy Lane, Lawrence Lessin, Mary Jo O’Sullivan, Jean Wactawski-Wende, Shagufta Yasmeen, and Ross Prentice. Alcohol Consumption and Risk of Postmenopausal Breast Cancer by Subtype: the Women’s Health Initiative Observational Study. Journal of the National Cancer Institute, 2010; DOI: 10.1093/jnci/djq316

Cite This Page:

Journal of the National Cancer Institute. "Alcohol intake increases certain types of breast cancer, study finds." ScienceDaily. ScienceDaily, 24 August 2010. <www.sciencedaily.com/releases/2010/08/100823162318.htm>.
Journal of the National Cancer Institute. (2010, August 24). Alcohol intake increases certain types of breast cancer, study finds. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2010/08/100823162318.htm
Journal of the National Cancer Institute. "Alcohol intake increases certain types of breast cancer, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/08/100823162318.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins