Featured Research

from universities, journals, and other organizations

LEDs illuminate eye for ocular disease screening

Date:
August 31, 2010
Source:
American Institute of Physics
Summary:
A new imaging system using six different wavelengths to illuminate the interior of the eyeball (ocular fundus) may pave the way for doctors to easily screen patients for common diseases of the eye, such as age-related macular degeneration and diabetic retinopathy.

A new imaging system using six different wavelengths to illuminate the interior of the eyeball (ocular fundus) may pave the way for doctors to easily screen patients for common diseases of the eye, such as age-related macular degeneration and diabetic retinopathy. The system is described in the journal Review of Scientific Instruments, which is published by the American Institute of Physics.

Related Articles


Currently, when optometrists and ophthalmogists visualize the ocular fundus, they typically take snapshot images of the eye in two or three wavelengths (red, green and blue), which can reveal some visually-apparent abnormalities. But an added dimension made possible with the imaging system described by Nicholas L. Everdell of University College London allows doctors to distinguish between the different light absorbing characteristics of biological molecules called chromophores.

According to the paper's coauthor Iain Styles of the University of Birmingham, five of these light-absorbing compounds are prevalent in the eye: retinal hemoglobins, choroidal hemoglobins, choroidal melanin, RPE (retinal pigment epithelium) melanin, and macular pigment. In a separate paper in Medical Image Analysis in 2006, Styles said that each of these has been shown to give rise to distinct variations in tissue coloration that can be discriminated in multispectral images.

In the new work, Everdell and Styles describe a device combining a high-sensitivity CCD camera with wavelength-specific illumination from LEDs (light-emitting diodes) that provides multispectral images of the ocular fundus. The multispectral images, explains Styles, are affected differently by the pigments present in the eye, and through a sophisticated algorithm they can be used to generate a pixel-by-pixel "parametric map" of the distribution of substances in the eye. Such maps may allow primary care clinicians to screen for and identify pathologies at a much earlier stage of development than other imaging modalities.

An advantage the new system offers over other multispectral retinal imaging systems is its speed. It can acquire a sequence of multispectral images at a fast enough rate (0. 5 seconds) to reduce image shifts caused by natural eye movements. In contrast with snapshot systems, the system's images retain full spatial resolution. Also, the system uses only the specific wavebands that are required for the subsequent analysis, minimizing the total light exposure of the subject, ensuring patient safety and improving image quality.

"The long term goal," Everdell said, "is to develop a system for chromophore quantification that is an integral part of the standard fundus camera, and therefore could be used routinely by both optometrists and opthalmologists."


Story Source:

The above story is based on materials provided by American Institute of Physics. Note: Materials may be edited for content and length.


Journal Reference:

  1. Everdell et al. Multispectral imaging of the ocular fundus using LED illumination. Proceedings of SPIE, 2009; 73711C DOI: 10.1117/12.831769

Cite This Page:

American Institute of Physics. "LEDs illuminate eye for ocular disease screening." ScienceDaily. ScienceDaily, 31 August 2010. <www.sciencedaily.com/releases/2010/08/100831141047.htm>.
American Institute of Physics. (2010, August 31). LEDs illuminate eye for ocular disease screening. ScienceDaily. Retrieved March 5, 2015 from www.sciencedaily.com/releases/2010/08/100831141047.htm
American Institute of Physics. "LEDs illuminate eye for ocular disease screening." ScienceDaily. www.sciencedaily.com/releases/2010/08/100831141047.htm (accessed March 5, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, March 5, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Bupa Eyes India Healthcare Opportunities

Bupa Eyes India Healthcare Opportunities

Reuters - Business Video Online (Mar. 5, 2015) — Bupa is hoping to expand in India&apos;s fast-growing health insurance market, once a rule change on foreign investment is implemented. The British private healthcare group&apos;s CEO tells Grace Pascoe why it&apos;s so keen on the new opportunity. Video provided by Reuters
Powered by NewsLook.com
Doctor in Your Pocket Is Getting Smarter

Doctor in Your Pocket Is Getting Smarter

Reuters - Business Video Online (Mar. 5, 2015) — Mobile apps are turning smartphones into a personal doctors, with users able to measure heart rate, blood pressure and even blood sugar. But will it change our behaviour? Ivor Bennett reports from the Mobile World Congress in Barcelona. Video provided by Reuters
Powered by NewsLook.com
AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

Newsy (Mar. 5, 2015) — AbbVie announced Wednesday it will buy cancer drugmaker Pharmacyclics in a $21 billion deal. Video provided by Newsy
Powered by NewsLook.com
Adults Only Get The Flu Twice A Decade, Researchers Say

Adults Only Get The Flu Twice A Decade, Researchers Say

Newsy (Mar. 4, 2015) — Researchers found adults only get the flu about once every five years. Scientists analyzed how a person&apos;s immunity builds up over time as well. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins