Featured Research

from universities, journals, and other organizations

Problem of fake medicines in developing countries could be solved, experts say

Date:
September 3, 2010
Source:
Lund University
Summary:
Counterfeiting of drugs is a huge industry. In Africa the situation is extremely serious. Half of the malaria medication sold there could be ineffective or even harmful. There is currently no good way to identify counterfeit drugs. However, researchers in Sweden and the UK have now developed a technique that could resolve the situation.

Counterfeiting of drugs is a huge industry with an annual turnover of more than SEK 500 billion. In Africa the situation is extremely serious. Half of the malaria medication sold there could be ineffective or even harmful. There is currently no good way to identify counterfeit drugs. However, researchers from Lund and the UK have now developed a technique that could resolve the situation.

Related Articles


In two years the researchers hope to have a prototype ready. It will resemble a small briefcase, in which a pharmacist, customs officer or pharmaceuticals agent can place a packet of tablets, without having to open the packet. After a minute or so the device indicates whether or not the medicine is fake.

"There are a number of advantages to this technique. It is not only reliable but also simple and cheap, which is a prerequisite if it is to be successfully put into use in developing countries," comments Andreas Jakobsson, Professor in Mathematical Statistics at Lund University and one of the researchers on the project.

The technique has its origins in the research that Andreas Jakobsson's Swedish and British colleagues usually conduct: detection of bombs and explosives. The researchers have been called on by HM Revenue and Customs in the UK to detect explosives at Heathrow Airport.

The research is based on a technique known as nuclear magnetic resonance. By exposing a substance to radio waves, the spin of the atom nuclei changes briefly. When the radio pulse is over and the resonance returns to normal, a weak signal, unique to each substance, is emitted. In this way, the researchers can usually work out what chemical substances are hiding in the material.

Researchers have long known that it should also be possible to use this technique to trace counterfeit drugs, but it has not been sufficiently well developed for this purpose. However, a recent breakthrough in the Swedish-British research group's work has changed that. Now they can also find out if a certain drug actually contains the active ingredient that the packaging claims.

"The signals that are emitted from a chemical substance are incredibly weak! But we have succeeded in developing mathematical algorithms which allow us to capture them. We have also managed to filter out interference from metals, for example, which are often found both in explosives and in the protective packaging around tablets," explains Andreas Jakobsson.

Professor Jakobsson and his Swedish colleague Erik Gudmundson are responsible for the mathematical calculations, while their colleagues at King's College London are responsible for the chemical experiments and the development of the equipment.

The researchers were recently awarded funding from the Wellcome Trust to develop a prototype. The Swedish research group is also funded by the Swedish Research Council and the Carl Trygger Foundation.

Counterfeit drugs are usually manufactured in factories in China and India and sold by the mafia and other criminal organisations. At best the drug only contains harmless binders. However, sometimes the manufacturers add rat poison or other cheap but harmful substances that can easily be formed into tablets. Some contain a weak dose of the active ingredient, which can be particularly harmful in the case of penicillin, for example, when it is important to ensure that all the bacteria are killed. Some counterfeit products work, but entail a loss of revenue for pharmaceutical companies.

Even if the problem is greatest in developing countries (in India, it is estimated that 15-20 per cent of all drugs are fake), counterfeit drugs are also found in Europe. Most of the drugs that can be purchased on the Internet are counterfeit.


Story Source:

The above story is based on materials provided by Lund University. Note: Materials may be edited for content and length.


Cite This Page:

Lund University. "Problem of fake medicines in developing countries could be solved, experts say." ScienceDaily. ScienceDaily, 3 September 2010. <www.sciencedaily.com/releases/2010/09/100901073356.htm>.
Lund University. (2010, September 3). Problem of fake medicines in developing countries could be solved, experts say. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2010/09/100901073356.htm
Lund University. "Problem of fake medicines in developing countries could be solved, experts say." ScienceDaily. www.sciencedaily.com/releases/2010/09/100901073356.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins