Featured Research

from universities, journals, and other organizations

High stress hormone levels linked to increased cardiovascular mortality

Date:
September 10, 2010
Source:
The Endocrine Society
Summary:
High levels of the stress hormone cortisol strongly predict cardiovascular death among both persons with and without pre-existing cardiovascular disease, according to a new study.

High levels of the stress hormone cortisol strongly predict cardiovascular death among both persons with and without pre-existing cardiovascular disease according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

Related Articles


In stressful situations, the body responds by producing the hormone cortisol. The effects of cortisol are intended to help the body recover from stress and regain a status of homeostasis, however chronically elevated cortisol levels have been associated with cardiovascular risk factors, such as the metabolic syndrome and accelerated atherosclerosis.

"Previous studies have suggested that cortisol might increase the risk of cardiovascular mortality, but until now, no study had directly tested this hypothesis," said Nicole Vogelzangs, PhD, of VU University Medical Center in The Netherlands and lead author of the study. "The results of our study clearly show that cortisol levels in a general older population predict cardiovascular death, but not other causes of mortality."

In this study, researchers evaluated 861 people aged 65 years and older who participated in a prospective cohort study. Within six years of the beginning of the study 183 participants had died. Urinary cortisol levels of subjects were measured at the beginning of the study and cause of death was ascertained from death certificates. Researchers found that urinary cortisol did not increase the risk of non-cardiovascular mortality but did increase cardiovascular mortality risk. The third of the subjects with the highest urinary cortisol had a five-fold increased risk of dying of cardiovascular disease.

"Cortisol is an important component of the stress system of the human body but in higher concentrations can be harmful," said Vogelzangs. "Our study shows that older persons with high levels of cortisol have an increased risk of dying from cardiovascular disease. This finding significantly adds evidence to the belief that cortisol can be damaging to the cardiovascular system."

Other researchers working on the study include: Aartjan Beekman and Brenda Penninx of VU University Medical Center in The Netherlands; Yuri Milaneschi and Luigi Ferrucci of the National Institute on Aging in Baltimore, Md.; and Stefania Bandinelli of Azienda Sanitaria Firenze in Italy.


Story Source:

The above story is based on materials provided by The Endocrine Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. N. Vogelzangs, A. T. F. Beekman, Y. Milaneschi, S. Bandinelli, L. Ferrucci, B. W. J. H. Penninx. Urinary Cortisol and Six-Year Risk of All-Cause and Cardiovascular Mortality. Journal of Clinical Endocrinology & Metabolism, 2010; DOI: 10.1210/jc.2010-0192

Cite This Page:

The Endocrine Society. "High stress hormone levels linked to increased cardiovascular mortality." ScienceDaily. ScienceDaily, 10 September 2010. <www.sciencedaily.com/releases/2010/09/100909073909.htm>.
The Endocrine Society. (2010, September 10). High stress hormone levels linked to increased cardiovascular mortality. ScienceDaily. Retrieved November 1, 2014 from www.sciencedaily.com/releases/2010/09/100909073909.htm
The Endocrine Society. "High stress hormone levels linked to increased cardiovascular mortality." ScienceDaily. www.sciencedaily.com/releases/2010/09/100909073909.htm (accessed November 1, 2014).

Share This



More Health & Medicine News

Saturday, November 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins