Featured Research

from universities, journals, and other organizations

High stress hormone levels linked to increased cardiovascular mortality

Date:
September 10, 2010
Source:
The Endocrine Society
Summary:
High levels of the stress hormone cortisol strongly predict cardiovascular death among both persons with and without pre-existing cardiovascular disease, according to a new study.

High levels of the stress hormone cortisol strongly predict cardiovascular death among both persons with and without pre-existing cardiovascular disease according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

Related Articles


In stressful situations, the body responds by producing the hormone cortisol. The effects of cortisol are intended to help the body recover from stress and regain a status of homeostasis, however chronically elevated cortisol levels have been associated with cardiovascular risk factors, such as the metabolic syndrome and accelerated atherosclerosis.

"Previous studies have suggested that cortisol might increase the risk of cardiovascular mortality, but until now, no study had directly tested this hypothesis," said Nicole Vogelzangs, PhD, of VU University Medical Center in The Netherlands and lead author of the study. "The results of our study clearly show that cortisol levels in a general older population predict cardiovascular death, but not other causes of mortality."

In this study, researchers evaluated 861 people aged 65 years and older who participated in a prospective cohort study. Within six years of the beginning of the study 183 participants had died. Urinary cortisol levels of subjects were measured at the beginning of the study and cause of death was ascertained from death certificates. Researchers found that urinary cortisol did not increase the risk of non-cardiovascular mortality but did increase cardiovascular mortality risk. The third of the subjects with the highest urinary cortisol had a five-fold increased risk of dying of cardiovascular disease.

"Cortisol is an important component of the stress system of the human body but in higher concentrations can be harmful," said Vogelzangs. "Our study shows that older persons with high levels of cortisol have an increased risk of dying from cardiovascular disease. This finding significantly adds evidence to the belief that cortisol can be damaging to the cardiovascular system."

Other researchers working on the study include: Aartjan Beekman and Brenda Penninx of VU University Medical Center in The Netherlands; Yuri Milaneschi and Luigi Ferrucci of the National Institute on Aging in Baltimore, Md.; and Stefania Bandinelli of Azienda Sanitaria Firenze in Italy.


Story Source:

The above story is based on materials provided by The Endocrine Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. N. Vogelzangs, A. T. F. Beekman, Y. Milaneschi, S. Bandinelli, L. Ferrucci, B. W. J. H. Penninx. Urinary Cortisol and Six-Year Risk of All-Cause and Cardiovascular Mortality. Journal of Clinical Endocrinology & Metabolism, 2010; DOI: 10.1210/jc.2010-0192

Cite This Page:

The Endocrine Society. "High stress hormone levels linked to increased cardiovascular mortality." ScienceDaily. ScienceDaily, 10 September 2010. <www.sciencedaily.com/releases/2010/09/100909073909.htm>.
The Endocrine Society. (2010, September 10). High stress hormone levels linked to increased cardiovascular mortality. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2010/09/100909073909.htm
The Endocrine Society. "High stress hormone levels linked to increased cardiovascular mortality." ScienceDaily. www.sciencedaily.com/releases/2010/09/100909073909.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins