Featured Research

from universities, journals, and other organizations

Appetite hormones may predict weight regain after dieting

Date:
September 11, 2010
Source:
The Endocrine Society
Summary:
Many people have experienced the frustration that comes with regaining weight that was lost from dieting. According to a new study, the levels of appetite hormones in the body prior to dieting may serve as a predictor of weight regain after dieting.

Many people have experienced the frustration that comes with regaining weight that was lost from dieting. According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), the levels of appetite hormones in the body prior to dieting may serve as a predictor of weight regain after dieting.

"Treating obesity with drugs or dietary programs can be very effective in the short-term, but the long-term success of maintaining the weight lost is usually poor," said Ana Crujeiras, PhD, of Compejo Hospitalario Universitario de Santiago in Spain and lead author of the study. "Our study sheds light on how the appetite hormones leptin and ghrelin affect weight regain after weight loss. This knowledge could be used as a tool to personalize weight-loss programs that could guarantee success in keeping off the weight."

In this study, researchers evaluated a group of 104 obese or overweight men and women during an 8-week low-calorie diet and again 32 weeks after treatment. Researchers measured body weight as well as plasma fasting ghrelin, leptin and insulin concentrations before, during and after dieting. They found that subjects with higher plasma leptin and lower ghrelin levels before dieting were more prone to regain weight lost after dieting and that these hormone levels could be proposed as biomarkers for predicting obesity-treatment outcomes.

"We believe this research is of foremost relevance in clinical terms as it may indicate that the outcome of weight therapy may be pre-conditioned," said Crujeiras. "Furthermore, our findings may provide endocrinology and nutrition professionals a tool to identify individuals in need of specialized weight-loss programs that first target appetite hormone levels before beginning conventional dietary treatment."

Other researchers working on the study include: Estíbaliz Goyenechea, Itziar Abete and J. Alfredo Martínez of the University of Navarra in Spain; and Mary Lage, Marcos Carreira and Felipe Casanueva of Compejo Hospitalario Universitario de Santiago in Spain. Both research groups belong to the Centro de Investigación Biomédica en Red de la Fisiopatología de la Obesidad y Nutrición (CIBERobn), an Instituto de Salud Carlos III iniciative.


Story Source:

The above story is based on materials provided by The Endocrine Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ana B. Crujeiras, Estíbaliz Goyenechea, Itziar Abete, Mary Lage, Marcos C. Carreira, J Alfredo Martínez, Felipe F. Casanueva. Weight Regain after a Diet-Induced Loss Is Predicted by Higher Baseline Leptin and Lower Ghrelin Plasma Levels. Journal of Clinical Endocrinology & Metabolism, 2010; DOI: 10.1210/jc.2009-2566

Cite This Page:

The Endocrine Society. "Appetite hormones may predict weight regain after dieting." ScienceDaily. ScienceDaily, 11 September 2010. <www.sciencedaily.com/releases/2010/09/100909073911.htm>.
The Endocrine Society. (2010, September 11). Appetite hormones may predict weight regain after dieting. ScienceDaily. Retrieved April 16, 2014 from www.sciencedaily.com/releases/2010/09/100909073911.htm
The Endocrine Society. "Appetite hormones may predict weight regain after dieting." ScienceDaily. www.sciencedaily.com/releases/2010/09/100909073911.htm (accessed April 16, 2014).

Share This



More Mind & Brain News

Wednesday, April 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Are School Dress Codes Too Strict?

Are School Dress Codes Too Strict?

AP (Apr. 16, 2014) — Pushing the limits on style and self-expression is a rite of passage for teens and even younger kids. How far should schools go with their dress codes? The courts have sided with schools in an era when school safety is paramount. (April 16) Video provided by AP
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) — A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Cognitive Function: Is It All Downhill From Age 24?

Cognitive Function: Is It All Downhill From Age 24?

Newsy (Apr. 15, 2014) — A new study out of Canada says cognitive motor performance begins deteriorating around age 24. Video provided by Newsy
Powered by NewsLook.com
App Fights Jet Lag With The Power Of Math

App Fights Jet Lag With The Power Of Math

Newsy (Apr. 13, 2014) — Researchers at the University of Michigan have designed an app to fight jet lag by adjusting your body's light intake. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins